Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
2 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
3 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
4 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
5 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
6 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
7 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
8 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
9 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
10 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
11 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
12 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
13 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
14 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
15 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
16 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
17 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
18 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
19 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
20 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
21 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
22 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
23 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
24 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
25 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
26 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
27 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
28 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
29 | B cell receptor signaling pathway 💬 Related to 17 target genes, 22 drugs (DrugBank) and 66 diseases in DDrare |
BTK [1] BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 300 [2] 300, 331 💬 |
30 | B cell receptor signaling pathway 💬 Related to 17 target genes, 22 drugs (DrugBank) and 66 diseases in DDrare |
CD19 [1] CD19 💬 |
D11757 D11757 💬 |
Inebilizumab | 011 [4] 11, 13, 51, 300 💬 |
31 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
DHODH [1] DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 |
32 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
33 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
34 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
35 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00664 D00664 💬 |
Cetirizine | 013 [4] 13, 28, 35, 300 💬 |
36 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D07662 D07662 💬 |
Cetirizine | 013 [4] 13, 28, 35, 300 💬 |
37 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
38 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00669 D00669 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
39 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D02419 D02419 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
40 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03285 D03285 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
41 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03360 D03360 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
42 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03854 D03854 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
43 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 [7] 6 , 46, 61, 86, 98, 107, 300 💬 |
44 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
45 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
46 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
47 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
48 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
49 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
50 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
51 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
52 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNFSF13B [1] TNFSF13B 💬 |
D03068 D03068 💬 |
Belimumab | 011 [12] 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬 |
53 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
54 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
55 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
56 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
57 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
58 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 49 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
59 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
BTK [1] BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 300 [2] 300, 331 💬 |
60 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CD19 [1] CD19 💬 |
D11757 D11757 💬 |
Inebilizumab | 011 [4] 11, 13, 51, 300 💬 |
61 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
62 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
63 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
BTK [1] BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 300 [2] 300, 331 💬 |
64 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
65 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
66 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
67 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
68 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 [7] 6 , 46, 61, 86, 98, 107, 300 💬 |
69 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
70 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
71 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
72 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
CD19 [1] CD19 💬 |
D11757 D11757 💬 |
Inebilizumab | 011 [4] 11, 13, 51, 300 💬 |
73 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
MS4A1 [1] MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 006 [49] 6 , 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
74 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
75 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
76 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
77 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
78 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
79 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
80 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
81 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
82 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
83 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
84 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
85 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
86 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
87 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
88 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
89 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
90 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
91 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
92 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
93 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
94 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
95 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
96 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
97 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
98 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
99 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00664 D00664 💬 |
Cetirizine | 013 [4] 13, 28, 35, 300 💬 |
100 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D07662 D07662 💬 |
Cetirizine | 013 [4] 13, 28, 35, 300 💬 |
101 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
102 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00669 D00669 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
103 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D02419 D02419 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
104 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03285 D03285 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
105 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03360 D03360 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
106 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03854 D03854 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
107 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
108 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
109 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
110 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
111 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
112 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
TNFSF13B [1] TNFSF13B 💬 |
D03068 D03068 💬 |
Belimumab | 011 [12] 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬 |
113 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
CD86 [1] CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
114 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
115 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
116 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
117 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
118 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
119 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
120 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
121 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
122 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
123 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
124 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
125 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
126 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DHODH [1] DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 |
127 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
128 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
129 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
130 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
131 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
132 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
133 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
134 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
135 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
136 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
137 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
138 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
139 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00664 D00664 💬 |
Cetirizine | 013 [4] 13, 28, 35, 300 💬 |
140 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D07662 D07662 💬 |
Cetirizine | 013 [4] 13, 28, 35, 300 💬 |
141 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
142 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00669 D00669 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
143 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D02419 D02419 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
144 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03285 D03285 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
145 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03360 D03360 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
146 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03854 D03854 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
147 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 [7] 6 , 46, 61, 86, 98, 107, 300 💬 |
148 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
149 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00751 D00751 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
150 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00979 D00979 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
151 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D05000 D05000 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
152 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D05001 D05001 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
153 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D05002 D05002 💬 |
Methylprednisolone | 002 [48] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
154 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00472 D00472 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
155 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00980 D00980 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
156 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00981 D00981 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
157 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00982 D00982 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
158 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01239 D01239 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
159 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D01998 D01998 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
160 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D02156 D02156 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
161 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D03301 D03301 💬 |
Prednisolone | 003 [43] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
162 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 [48] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
163 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
BTK [1] BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 300 [2] 300, 331 💬 |
164 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
165 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
166 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
167 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
TNFSF13B [1] TNFSF13B 💬 |
D03068 D03068 💬 |
Belimumab | 011 [12] 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬 |
168 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
169 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
170 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
171 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
172 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
BTK [1] BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 300 [2] 300, 331 💬 |
173 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
174 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
175 | Ovarian steroidogenesis 💬 Related to 6 target genes, 35 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
176 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
177 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
178 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
179 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
180 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
181 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
182 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
183 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
184 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
185 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CD19 [1] CD19 💬 |
D11757 D11757 💬 |
Inebilizumab | 011 [4] 11, 13, 51, 300 💬 |
186 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
BTK [1] BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 300 [2] 300, 331 💬 |
187 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 [1] PTGS1 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
188 | Primary immunodeficiency 💬 Related to 11 target genes, 21 drugs (DrugBank) and 27 diseases in DDrare |
BTK [1] BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 300 [2] 300, 331 💬 |
189 | Primary immunodeficiency 💬 Related to 11 target genes, 21 drugs (DrugBank) and 27 diseases in DDrare |
CD19 [1] CD19 💬 |
D11757 D11757 💬 |
Inebilizumab | 011 [4] 11, 13, 51, 300 💬 |
190 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
191 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
192 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
193 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
194 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
195 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
196 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
197 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
198 | Pyrimidine metabolism 💬 Related to 4 target genes, 8 drugs (DrugBank) and 36 diseases in DDrare |
DHODH [1] DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 |
199 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
200 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
201 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
202 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
203 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
204 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
TNFSF13B [1] TNFSF13B 💬 |
D03068 D03068 💬 |
Belimumab | 011 [12] 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬 |
205 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 56 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
206 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 56 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
207 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
208 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
209 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
210 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
211 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
212 | Small cell lung cancer 💬 Related to 14 target genes, 38 drugs (DrugBank) and 58 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
213 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
214 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
215 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
216 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
217 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
218 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
219 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
220 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
221 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
222 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
223 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
224 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
225 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
226 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
227 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
228 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
229 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
230 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
CD86 [1] CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
231 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
232 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
233 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
234 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
235 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
236 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
237 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
238 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
239 | Viral myocarditis 💬 Related to 30 target genes, 20 drugs (DrugBank) and 47 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
240 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
241 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
242 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
243 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |