Ammonia ( DrugBank: Ammonia )


3 diseases
IDDisease name (Link within this page)Number of trials
86Pulmonary arterial hypertension1
88Chronic thromboembolic pulmonary hypertension1
296Biliary atresia1

86. Pulmonary arterial hypertension


Clinical trials : 1,181 Drugs : 701 - (DrugBank : 126) / Drug target genes : 105 - Drug target pathways : 192
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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Inclusion_
agemin
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agemax
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PhaseCountries
1NCT03344159
(ClinicalTrials.gov)
April 1, 201828/9/2017Spironolactone Therapy in Chronic Stable Right HF TrialSpironolactone Therapy in Chronic Stable Right HF TrialChronic Right-Sided Heart Failure;Pulmonary Arterial Hypertension;Pulmonary Hypertension, Primary, 2;Pulmonary Hypertension, Primary, 3;Pulmonary Hypertension, Primary, 4;Cardiomyopathy Right VentricularDrug: Spironolactone;Drug: Placebo;Radiation: PET/CT Scan: Two PET scans using 1. C-11 HED and 2. N-13 Ammonia or rubidium-82;Diagnostic Test: Cardiac MRI (Gadolinium enhanced)Ottawa Heart Institute Research CorporationNULLRecruiting18 YearsN/AAll30Phase 4Canada

88. Chronic thromboembolic pulmonary hypertension


Clinical trials : 159 Drugs : 118 - (DrugBank : 23) / Drug target genes : 13 - Drug target pathways : 53
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
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gender
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size
PhaseCountries
1NCT02094001
(ClinicalTrials.gov)
May 201417/3/2014Pilot Study to Evaluate Right Ventricular Function With Riociguat in CTEPHEvaluation of Right Ventricular Function and Metabolism Following Riociguat for the Treatment of Chronic Thromboembolic Pulmonary Hypertension- Images of RioChronic Thromboembolic Pulmonary HypertensionRadiation: Cardiac PET imaging using F-18-FDG, N-13 ammonia( NH3)Ottawa Heart Institute Research CorporationBayerCompleted18 YearsN/AAll6Phase 2Canada

296. Biliary atresia


Clinical trials : 63 Drugs : 65 - (DrugBank : 37) / Drug target genes : 45 - Drug target pathways : 63
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1ChiCTR2100044533
2021-06-012021-03-23Multicenter study of non-invasive diagnostic scoring system for biliary atresiaMulticenter study of non-invasive diagnostic scoring system for biliary atresia Biliary atresiaGold Standard:Intraoperative cholangiography;Index test:Non-invasive diagnostic scoring system for biliary atresia (Biochemicaltests, blood routine, CRP, blood ammonia, AFP, hepatobiliary B ultrasound);Children's Hospital Affiliated to Zhejiang University Medical CollegeNULLRecruitingBothTarget condition:200;Difficult condition:0China