Drug（薬物リスト） DrugBank | All Description Patterns💬 Info on mouse-over

No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	20 mg sildenafil citrate by mouth	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
2	5% sildenafil cream	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 50 💬
3	Access program - sildenafil citrate, viagra, revatio	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
4	Bosentan and sildenafil	Bosentan	4件: D01227, D02229, D07538, D08514 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
5	Duo-therapy with sildenafil + bosentan	Bosentan	4件: D01227, D02229, D07538, D08514 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
6	Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan)	Bosentan	6件: D01227, D02008, D02229, D07538, D08514, D10135 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
7	G04be03- sildenafil - sildenafil (citrato)	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
8	Mono-therapy with sildenafil	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
9	Oral sildenafil	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
10	Other: standard of care sildenafil	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	2件: 90, 301 💬
11	Sildenafil	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
12	Sildenafil (50 mg)	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 85 💬
13	Sildenafil (acute-1 hour)	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 299 💬
14	Sildenafil (as citrate)	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
15	Sildenafil (revatio)	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
16	Sildenafil (revatio) 20 mg tid	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
17	Sildenafil (subchronic-4 weeks)	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 299 💬
18	Sildenafil 20 mg tablets	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 278 💬
19	Sildenafil 20mg	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	2件: 51, 86 💬
20	Sildenafil 20mg and bosentan 62.5mg	Bosentan	4件: D01227, D02229, D07538, D08514 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	2件: 51, 86 💬
21	Sildenafil 40mg oral capsule	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 299 💬
22	Sildenafil and losartan	Losartan	4件: D00357, D02229, D08146, D08514 💬	2件: AGTR1, PDE5A 💬	18件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Purine metabolism, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	1件: 85 💬
23	Sildenafil by injection	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 210 💬
24	Sildenafil citrate	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	4件: 51, 85, 86, 225 💬
25	Sildenafil citrate (uk-92,480)	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
26	Sildenafil filmtabletten	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
27	Sildenafil singly or in association with bosentan	Bosentan	4件: D01227, D02229, D07538, D08514 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
28	Sildenafil therapy	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 51 💬
29	Sildenafil25 mg	-	-	-	-	1件: 17 💬
30	Sildenafilo	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
31	Sitaxsentan and sildenafil	Sildenafil	3件: D02229, D07171, D08514 💬	2件: EDNRA, PDE5A 💬	9件: Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
32	Sodium tanshinone iia sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth	Dextrose, unspecified form	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 86 💬
33	Tadalafil and sildenafil	Sildenafil	3件: D02008, D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 113 💬

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