DDrare: Database of Drug Development for Rare Diseases

211. 左心低形成症候群
［臨床試験数：20，薬物数：28（DrugBank：9），標的遺伝子数：5，標的パスウェイ数：13］

Searched query = "Hypoplastic left heart syndrome", "HLHS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = Allo-hMSCs; Ambrisentan; Autologous (self) mononuclear cells derived from umbilical cord blood; Autologous Human Placental Cord Blood Mononuclear Cells; Autologous Umbilical Cord Blood; Autologous cell-based delivery; Bosentan; C-kit+ cells; Curosurf; Erythropoetin; Longeveron Mesenchymal Stem Cells; METHYLPREDNISOLONE SODIUM SUCCINATE; MPC; Maternal Hyperoxygenation; Maternal hyperoxygenation; Methylprednisolone; Metyyliprednisoloninatriumsuksinaatti; Nitrogen; Normal saline; Oxandrolone; Procedure: Stage II Surgical repair; Rexlemestrocel-L; Sham; Sildenafil; Solu-Medrol; Solu-medrol; Tracleer; Vitamin C

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00507819 (ClinicalTrials.gov)	December 2007	25/7/2007	Sildenafil After the Fontan Operation	The Sildenafil After Fontan Operation Study	Hypoplastic Left Heart Syndrome;Tricuspid Atresia	Drug: Sildenafil;Drug: Placebo	Children's Hospital of Philadelphia	The Mark H. and Blanche M. Harrington Foundation	Completed	8 Years	40 Years	All	28	Phase 2	United States

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT00507819
(ClinicalTrials.gov)

December 2007

25/7/2007

Sildenafil After the Fontan Operation

The Sildenafil After Fontan Operation Study

Hypoplastic Left Heart Syndrome;Tricuspid Atresia

Drug: Sildenafil;Drug: Placebo

Children's Hospital of Philadelphia

The Mark H. and Blanche M. Harrington Foundation

Completed

8 Years

40 Years

All

Phase 2

United States