22. Moyamoya disease
[
8 clinical trials,
11 drugs（DrugBank:
10 drugs),
19 target genes / 30 target pathways ]
Searched query = "Moyamoya disease", "Occlusive disease in circle of Willis"
The queries were searched in Public_title, Scientific_title, and Condition of the data. Export date: 11/21/2019, 11/20/2019. Trials are sorted by Date_enrolment from most recent to oldest in the table.
| No. | TrialID | Date_ enrollement | Last_Refreshed_ on | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ChiCTR1900027197 | 2019-05-01 | 11 November 2019 | Effects of desflurane on cerebral oxygen supply-consumption balance in cerebral revascularization | Study for the protective effect of desflurane on the brain of patients with moyamoya disease | moyamoya disease | Group 2:Desflurane for anesthesia maintenance;Group 1:propofol; | The First Affiliated Hospital of Zhengzhou University | Not Recruiting | 20 | 65 | Both | Group 2:20;Group 1:20; | Phase 4 | China | |
| 2 | NCT03882060 | April 8, 2019 | 23 April 2019 | Effect of Recombinant Human EPO on the Postoperative Neurologic Outcome in Pediatric Moyamoya Patients | The Effect of Recombinant Human Erythropoietin on the Postoperative Neurologic Outcome in Pediatric Moyamoya Disease Patients - A Double Blind Randomized Controlled Trial | Moyamoya Disease;Pediatrics;Cerebrovascular Disorders | Drug: erythropoietin;Drug: Normal saline | Seoul National University Hospital | Recruiting | N/A | 18 Years | All | 82 | N/A | Korea, Republic of | |
| 3 | ChiCTR1800020377 | 2019-01-01 | 14 January 2019 | Aspirin in Moyamoya Disease | The Clinical Benefit and Risk of Oral Aspirin for Moyamoya Disease | moyamoya disease | Case series:Aspirin; | Beijing Tiantan Hospital, Capital Medical University | Recruiting | 8 | 60 | Both | Case series:300; | Other | China | |
| 4 | JPRN-jRCTs031180017 | 01/08/2018 | 22 July 2019 | Studies on the utility of simultaneous-multi-slice acquisition (SMS) dynamic susceptibility contrast-enhanced (DSC)MRI for the occulusive cerebrobascular disease | Studies on the utility of simultaneous-multi-slice acquisition (SMS) dynamic susceptibility contrast-enhanced (DSC)MRI for the occulusive cerebrobascular disease - SMS DSC-MRI study for the occulusive cerebrobascular disease | carotid artery stenosis, moyamoya disease | Intravenous administration of gadobutrol (Gadovist, Bayer Schering Pharma, Berlin, Germany) is administered in the supine position, and high speed DSC-MRI scan by using SMS acquisition (temporal resolution of 0.5s) is carried out at the same time as injection of the contrast agent with an acquisition time of 70sec. The quantitative and qualitative comparison between reference data set (0.5s) and additional data sets with temporal resolution of 1.0s, 1.5s, and 2.0s generated from the reference data set, is performed. | Shigeki Aoki | Bayer Yakuhin, Ltd;Bayer Yakuhin, Ltd | Recruiting | >=20 age old | Both | 50 | N/A | none | |
| 5 | NCT02510586 | August 2015 | 3 August 2015 | Sevoflurane and Hyperperfusion Syndrome | Effect of Sevoflurane-induced Postconditioning on the Incidence of Postoperative Cerebral Hyperperfusion Syndrome After Revascularization Surgery in Adult Patients With Moyamoya Disease | Hyperperfusion Syndrome;Moyamoya Disease | Drug: Sevoflurane | Seoul National University Hospital | Not recruiting | 18 Years | N/A | Both | 152 | N/A | ||
| No. | TrialID | Date_ enrollement | Last_Refreshed_ on | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 6 | JPRN-UMIN000008742 | 2012/09/01 | 2 April 2019 | Studies on the effect of free radical scavenger Edaravone against postoperative hyper-perfusion syndrome after STA-MCA bypass surgery for adult moyamoya disease. | moyamoya disease | Administration of edaravone from preoperative to postoperative day 7. | Department of Neurosurgery, Hokkaido University Graduate School of Medicine | Not Recruiting | 16years-old | Not applicable | Male and Female | 32 | Not applicable | Japan | ||
| 7 | NCT03162588 | May 1, 2010 | 16 December 2017 | Multiple Burrhole Therapy With Erythropoietin for Unstable Moyamoya | Feasibility Study of Multiple Burrhole Therapy Combined With Intravenous Erythropoietin Pretreatment for Unstable Moyamoya | Ischemic Attack;Ischemic Stroke;Moyamoya Disease;Burr Hole;Angiogenesis | Drug: erythropoietin | Ajou University School of Medicine | Not recruiting | 16 Years | N/A | All | 37 | Phase 1/Phase 2 | Korea, Republic of | |
| 8 | NCT01419275 | April 2009 | 16 December 2017 | Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients | Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients | Cerebrovascular Accident;Moyamoya Disease | Drug: Xenon contrast agent;Device: Magnetic Resonance Imaging | Stanford University | Not recruiting | N/A | N/A | All | 126 | N/A | United States |