DDrare: Database of Drug Development for Rare Diseases

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230. Alveolar hypoventilation syndrome
[ 5 clinical trials, 5 drugs（DrugBank: 3 drugs), 16 target genes / 25 target pathways ]

Searched query = "Alveolar hypoventilation syndrome", "Hypoventilation syndrome"
The queries were searched in Public_title, Scientific_title, and Condition of the data. Export date: 11/20/2019, 11/21/2019. Trials are sorted by Date_enrolment from most recent to oldest in the table.

Drug = Acetazolamide; Desogestrel; Domperidone; Ketogenic diet; Motilium

No.	TrialID	Date_ enrollement	Last_Refreshed_ on	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04108819	October 30, 2019	11 November 2019	Ketogenic Diet for Obesity Hypoventilation Syndrome	Ketogenic Diet for Obesity Hypoventilation Syndrome	Obesity Hypoventilation Syndrome;Ketogenic Dieting;Hypercapnic Respiratory Failure	Dietary Supplement: Ketogenic Diet	Johns Hopkins University	Recruiting	18 Years	75 Years	All	10	N/A	United States
2	NCT01500473	February 2012	19 February 2015	Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome	Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome	Congenital Central Hypoventilation Syndrome	Drug: Desogestrel	Children's Hospital Los Angeles	Not recruiting	16 Years	50 Years	Female	8	N/A	United States
3	NCT01499485	November 2011	30 March 2015	Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation.	Effects of Acetazolamide on the Duration of Mechanical Ventilation in Patients With Metabolic Alkalosis. Phase III Multicenter Double-blinded Clinical Trial.	Pulmonary Disease, Chronic Obstructive;Obesity Hypoventilation Syndrome;Metabolic Alkalosis	Drug: Acetazolamide;Drug: Placebo	Hospital Son Llatzer	Not recruiting	18 Years	N/A	Both	140	Phase 3	Spain
4	NCT01243697	April 2011	19 February 2015	Assessment of Desogestrel in Ondine Syndrome	Assessment of Desogestrel for a Pharmacological Recovery of Ventilatory Activity in Congenital Central Hypoventilation Syndrome - Ondine Syndrome	Ondine Syndrome	Drug: desogestrel	Assistance Publique - Hôpitaux de Paris	Not recruiting	10 Years	60 Years	Female	6	Phase 2/Phase 3	France
5	EUCTR2005-005950-33-SE	07/06/2006	19 March 2012	Studie av Domperidon och barn med kongenitalt centralt hypoventilationssyndrom. - DOMPCCHSSWE1	Studie av Domperidon och barn med kongenitalt centralt hypoventilationssyndrom. - DOMPCCHSSWE1	Congenital central hypoventilation syndrome, CCHS or Ondine's curse.	Trade Name: Motilium Product Name: Motilium Pharmaceutical Form: Oral suspension INN or Proposed INN: Domperidone Concentration unit: mg/ml milligram(s)/millilitre Concentration type: equal Concentration number: 1-	Karolinska Universitetssjukhuset	Authorised			Female: yes Male: yes			Sweden