329. Aniridia
[
3 clinical trials,
2 drugs(DrugBank:
2 drugs),
0 target gene / 0 target pathway ]
Searched query = "Aniridia"
The queries were searched in Public_title, Scientific_title, and Condition of the data. Export date: 11/20/2019, 11/21/2019. Trials are sorted by Date_enrolment from most recent to oldest in the table.
No. | TrialID | Date_ enrollement | Last_Refreshed_ on | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NCT04117880 | December 31, 2018 | 22 October 2019 | A Phase 2 Open Label Extension Study in Participants With Nonsense Mutation Aniridia | Nonsense Mutation Aniridia: An Ataluren (PTC124) Phase 2 Extension Study | Aniridia | Drug: Ataluren | PTC Therapeutics | Not recruiting | 2 Years | N/A | All | 0 | Phase 2 | ||
2 | NCT02647359 | January 31, 2016 | 14 October 2019 | Study of Ataluren in Participants With Nonsense Mutation Aniridia | STAR: A Phase 2, Multicenter, Randomized, Double-Masked, Placebo-Controlled Study of the Safety and Efficacy of Ataluren (PTC124) for the Treatment of Nonsense Mutation Aniridia | Aniridia | Drug: Ataluren;Drug: Placebo | PTC Therapeutics | Not recruiting | 2 Years | N/A | All | 39 | Phase 2 | United States;Canada | |
3 | JPRN-UMIN000002948 | 2013/04/01 | 2 April 2019 | Cultivated epithelial sheet transplantation for corneal epithelial stem cell deficiency | a) Steven's Johnson Syndrome b) Ocular cicatricial pemphigoid c) Chemical/ Thermal Burns of the Cornea d) Gelatinous Drop Like Dystrophy e) Salzmann Corneal Degeneration f) Congenital Aniridia | Corneal epithelial sheet transplantation Cultivated eptihealial sheet transplantation will be perfored in the surgical department of Keio University Hospital. Simultaneous lamellar keratoplasty will be allowed. Surgical procedure involves removal of all pannus and abnormal epithelial tissue, the use of 0.04% mitomycin C to prevent fibrosis, and transplantation of the cultivated sheet. | Department of Ophthalmology, Keio University School of Medicine | Not Recruiting | 20years-old | Not applicable | Male and Female | 5 | Not selected | Japan |