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 329. Aniridia
 [ 3 clinical trials,    2 drugs(DrugBank: 2 drugs),    0 target gene / 0 target pathway

Searched query = "Aniridia"
The queries were searched in Public_title, Scientific_title, and Condition of the data. Export date: 11/20/2019, 11/21/2019. Trials are sorted by Date_enrolment from most recent to oldest in the table.

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1NCT04117880December 31, 201822 October 2019A Phase 2 Open Label Extension Study in Participants With Nonsense Mutation AniridiaNonsense Mutation Aniridia: An Ataluren (PTC124) Phase 2 Extension StudyAniridiaDrug: AtalurenPTC TherapeuticsNot recruiting2 YearsN/AAll0Phase 2
2NCT02647359January 31, 201614 October 2019Study of Ataluren in Participants With Nonsense Mutation AniridiaSTAR: A Phase 2, Multicenter, Randomized, Double-Masked, Placebo-Controlled Study of the Safety and Efficacy of Ataluren (PTC124) for the Treatment of Nonsense Mutation AniridiaAniridiaDrug: Ataluren;Drug: PlaceboPTC TherapeuticsNot recruiting2 YearsN/AAll39Phase 2United States;Canada
3JPRN-UMIN0000029482013/04/012 April 2019Cultivated epithelial sheet transplantation for corneal epithelial stem cell deficiencya) Steven's Johnson Syndrome b) Ocular cicatricial pemphigoid c) Chemical/ Thermal Burns of the Cornea d) Gelatinous Drop Like Dystrophy e) Salzmann Corneal Degeneration f) Congenital AniridiaCorneal epithelial sheet transplantation
Cultivated eptihealial sheet transplantation will be perfored in the surgical department of Keio University Hospital. Simultaneous lamellar keratoplasty will be allowed.
Surgical procedure involves removal of all pannus and abnormal epithelial tissue, the use of 0.04% mitomycin C to prevent fibrosis, and transplantation of the cultivated sheet.
Department of Ophthalmology, Keio University School of MedicineNot Recruiting20years-oldNot applicableMale and Female5Not selectedJapan