42. Polyarteritis nodosa
[
9 clinical trials,
22 drugs（DrugBank:
15 drugs),
23 target genes / 48 target pathways ]
Searched query = "Polyarteritis nodosa"
The queries were searched in Public_title, Scientific_title, and Condition of the data. Export date: 11/21/2019, 11/20/2019. Trials are sorted by Date_enrolment from most recent to oldest in the table.
| No. | TrialID | Date_ enrollement | Last_Refreshed_ on | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03482479 | February 4, 2019 | 22 October 2019 | Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis | Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis | Eosinophilic Granulomatosis With Polyangiitis (EGPA);Churg-Strauss Syndrome (CSS);Giant Cell Arteritis;Granulomatosis With Polyangiitis;Microscopic Polyangiitis;Polyarteritis Nodosa;Takayasu Arteritis | Drug: Naltrexone Hydrochloride;Other: Placebo Comparator | University of Pennsylvania | Recruiting | 18 Years | N/A | All | 60 | Phase 2 | United States | |
| 2 | NCT02939573 | January 2017 | 11 November 2019 | A Randomized Multicenter Study for Isolated Skin Vasculitis | A Randomized Multicenter Study for Isolated Skin Vasculitis | Primary Cutaneous Vasculitis;Cutaneous Polyarteritis Nodosa;IgA Vasculitis;Henoch-Schönlein Purpura | Drug: Colchicine;Drug: Dapsone;Drug: Azathioprine | University of Pennsylvania | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS);National Center for Advancing Translational Science (NCATS);Office of Rare Diseases (ORD) | Recruiting | 18 Years | N/A | All | 90 | Phase 2 | United States;Canada |
| 3 | EUCTR2013-004668-71-GB | 25/09/2014 | 27 October 2014 | A study of treatment for polyarteritis nodosa in children | An Open Label Randomised Controlled Trial of Mycophenolate Mofetil Versus Cyclophosphamide for the Induction of Remission of Childhood Polyarteritis Nodosa - MYPAN | Childhood systemic polyarteritis nodosa (PAN) MedDRA version: 17.0 Level: LLT Classification code 10036026 Term: Polyarteritis nodosa of childhood System Organ Class: 100000004866 ;Therapeutic area: Diseases [C] - Immune System Diseases [C20] | Trade Name: CellCept Product Name: CellCept (Mycophenolate Mofetil) Pharmaceutical Form: Powder for oral suspension INN or Proposed INN: Mycophenolate mofetil CAS Number: 24280-93-1 Concentration unit: g/ml gram(s)/millilitre Concentration type: range Concentration number: 1g-5ml Trade Name: CellCept Product Name: CellCept (Mycophenolate Mofetil) Pharmaceutical Form: Capsule, hard INN or Proposed INN: Mycophenolate mofetil CAS Number: 24280-93-1 Concentration unit: mg milligram(s) Concentration type: not less then Concentration number: 250- Trade Name: CellCept (Mycophenolate Mofetil) Product Name: CellCept (Mycophenolate Mofetil) Pharmaceutical Form: Film-coated tablet INN or Proposed INN: Mycophenolate mofetil CAS Number: 24280-93-1 Concentration unit: mg milligram(s) Concentration type: not less then Concentration number: 500- Trade Name: Cyclophosphamide Product Name: Cyclophosphamide Pharmaceutical Form: Powder for solution for injection | University College London | Authorised | Female: yes Male: yes | 40 | Portugal;Slovenia;Greece;Spain;Turkey;United Kingdom;Italy;Czech Republic;Belgium;Poland;Croatia;Germany;Netherlands;Sweden | ||||
| 4 | NCT00751517 | September 2008 | 19 February 2015 | Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides | Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides. A Randomized Controlled Trial. | Wegener's Granulomatosis;Churg-Strauss Syndrome;Microscopic Polyangiitis;Polyarteritis Nodosa | Drug: Methotrexate;Drug: Cyclophosphamide | University of Parma | Not recruiting | 18 Years | 80 Years | Both | Phase 2 | Italy | ||
| 5 | NCT00647166 | May 2008 | 19 October 2015 | Association Corticosteroid/Azathioprine in Microscopic Polyangiitis/ Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome) | Evaluation of a New Treatment Strategy for Patients With Microscopic Polyangiitis, Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome) Without Poor Prognosis Factors | MPA;PAN or EGPA With FFS=0;At Diagnosis or Within the First 15 Days Following Initiation of Corticosteroids | Drug: corticosteroid and azathioprine;Drug: corticosteroid and placebo | Assistance Publique - Hôpitaux de Paris | Not recruiting | 18 Years | N/A | Both | 114 | Phase 3 | France | |
| No. | TrialID | Date_ enrollement | Last_Refreshed_ on | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 6 | NCT00307671 | July 2005 | 19 February 2015 | Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years | Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years Comparison of Two Strategies Combining Steroids With or Without Immunosuppressants | Vasculitis;Wegener's Granulomatosis;Microscopic Polyangiitis;Churg-Strauss Syndrome;Polyarteritis Nodosa | Drug: prednisone, methylprednisolone,cyclophosphamides;Drug: Cyclophosphamide, Azathioprine,prednisone,methylprednisolone;Drug: Mycophenolate mofetil,methotrexate | Assistance Publique - Hôpitaux de Paris | Not recruiting | 65 Years | N/A | Both | 108 | Phase 4 | France | |
| 7 | NCT00006055 | March 2000 | 19 February 2015 | Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases | Purpura, Schoenlein-Henoch;Graft Versus Host Disease;Anemia, Hemolytic, Autoimmune;Rheumatoid Arthritis;Churg-Strauss Syndrome;Hypersensitivity Vasculitis;Wegener's Granulomatosis;Systemic Lupus Erythematosus;Giant Cell Arteritis;Pure Red Cell Aplasia;Juvenile Rheumatoid Arthritis;Polyarteritis Nodosa;Autoimmune Thrombocytopenic Purpura;Takayasu Arteritis | Drug: anti-thymocyte globulin;Drug: cyclophosphamide;Drug: cyclosporine;Drug: filgrastim;Drug: methylprednisolone;Drug: prednisone;Procedure: Autologous Peripheral Blood Stem Cell Transplantation | Fairview University Medical Center | Not recruiting | 1 Year | 55 Years | Both | 10 | N/A | United States | ||
| 8 | NCT00400075 | July 1996 | 19 February 2015 | CHUSPAN PAN BP Treatment of Polyarteritis Nodosa and Microscopic Polyangiitis Without Poor-Prognosis Factors | CHUSPAN PAN BP Treatment of Polyarteritis Nodosa and Microscopic Polyangiitis Without Poor-Prognosis Factors a Prospective Randomized Study in 125 Patients | Polyarteritis Nodosa;Microscopic Polyangiitis | Drug: azathioprine;Drug: cyclophosphamide | Hospices Civils de Lyon | Not recruiting | 15 Years | 90 Years | Both | 124 | Phase 4 | Switzerland | |
| 9 | NCT00001457 | September 1995 | 19 February 2015 | Lamivudine for Chronic Hepatitis B | Lamivudine for Chronic Hepatitis B | Chronic Hepatitis B;Chronic Hepatitis D;Glomerulonephritis;Polyarteritis Nodosa | Drug: Lamivudine | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Not recruiting | N/A | N/A | Both | 60 | Phase 2 | United States |