Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-{[4’-----[1] 79 💬
21,2-Dihexadecanoyl-sn-Glycero-3-Phospho-(1-raac-glycerol)[1] Glycerin[1] Glycerin 💬--[1] 79 💬
3AAV directed hLDLR gene therapy----[1] 79 💬
4AAV8.TBG.hLDLR----[1] 79 💬
5Acetate[1] Acetate---[41] 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
6AEGR-733----[1] 79 💬
7AK102----[1] 79 💬
8AKCEA-ANGPTL3-LRX----[2] 79, 265 💬
9ALIROCUMAB[1] Alirocumab[1] Alirocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
10Alirocumab SAR236553 (REGN727)[1] Alirocumab[1] Alirocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
11ALN-60212----[1] 79 💬
12ALN-PCSSC[1] Inclisiran[1] Inclisiran 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
13AMG 145----[1] 79 💬
14AMG145----[1] 79 💬
15ANACETRAPIB[1] Anacetrapib[1] Anacetrapib 💬[1] CETP 💬[1] Cholesterol metabolism 💬[1] 79 💬
16ARO-ANG 3 Injection----[1] 79 💬
17Atorvastatin[1] Atorvastatin[1] Atorvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
18Calcium[2] Calcium,
Calcium carbonate		[2] Calcium carbonate ,
Calcium carbonate 💬		--[27] 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
19Calcium rosuvastatin[2] Calcium,
Rosuvastatin		[1] Rosuvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 79 💬
20CER-001----[1] 79 💬
21Cholestyramine[1] Cholestyramine---[2] 13, 79 💬
22Comparator: ezetimibe[1] Ezetimibe[1] Ezetimibe 💬[1] NPC1L1 💬[1] Fat digestion and absorption 💬[2] 79, 260 💬
23Crestor[1] Rosuvastatin[1] Rosuvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 49, 79, 299 💬
24Crestor Film-Coated Tablet[1] Rosuvastatin[1] Rosuvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 79 💬
25Crestor Tablets (calcium rosuvastatin) Film-Coated tablets[2] Calcium,
Rosuvastatin		[1] Rosuvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 79 💬
26Current lipid-lowering treatment----[1] 79 💬
27DPPG----[1] 79 💬
28EVINACUMAB[1] Evinacumab[1] Evinacumab 💬[1] ANGPTL3 💬[1] Cholesterol metabolism 💬[1] 79 💬
29Evinacumab (REGN1500)[1] Evinacumab[1] Evinacumab 💬[1] ANGPTL3 💬[1] Cholesterol metabolism 💬[1] 79 💬
30EVOLOCUMAB[1] Evolocumab[1] Evolocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[2] 79, 222 💬
31Evolocumab (AMG 145)[1] Evolocumab[1] Evolocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
32Ezetimibe[1] Ezetimibe[1] Ezetimibe 💬[1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260 💬
33Fenofibrate[1] Fenofibrate[1] Fenofibrate 💬[1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
34Fluvastatin[1] Fluvastatin[1] Fluvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 79, 218, 222 💬
35Gemcabene[1] Gemcabene---[2] 79, 265 💬
36Gene analysis----[1] 79 💬
37Glycerol[1] Glycerin[1] Glycerin 💬--[5] 6, 13, 79, 316, 317 💬
38IBI306----[1] 79 💬
39Implitapide[1] Implitapide---[1] 79 💬
40Inclisiran[1] Inclisiran[1] Inclisiran 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
41Inclisiran Sodium[1] Inclisiran[1] Inclisiran 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
42Inclisiran Sodium for injection[1] Inclisiran[1] Inclisiran 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
43ISIS 301012----[1] 79 💬
44ISIS 301012 phosphorothioate oligonucleotide----[1] 79 💬
45ISIS 703802----[1] 79 💬
46JS002----[1] 79 💬
47KJX839----[1] 79 💬
48Lapaquistat[1] Lapaquistat---[1] 79 💬
49Lapaquistat acetate and current lipid-lowering treatment[2] Acetate,
Lapaquistat		---[1] 79 💬
50Leqvio[1] Inclisiran[1] Inclisiran 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
51Leqvio 284 mg solution for injection in pre-filled syringe[1] Inclisiran[1] Inclisiran 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
52Lerodalcibep----[1] 79 💬
53LIB003----[1] 79 💬
54Lojuxta[1] Lomitapide[1] Lomitapide 💬[1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79 💬
55Lojuxta 10 mg hard capsules[1] Lomitapide[1] Lomitapide 💬[1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79 💬
56Lojuxta 20 mg hard capsules[1] Lomitapide[1] Lomitapide 💬[1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79 💬
57Lojuxta 5 mg hard capsules[1] Lomitapide[1] Lomitapide 💬[1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79 💬
58LOMITAPIDE[1] Lomitapide[1] Lomitapide 💬[1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79 💬
59Lomitapide 2mg hard capsules[1] Lomitapide[1] Lomitapide 💬[1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79 💬
60Lovastatin[1] Lovastatin[1] Lovastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
61MBX-8025----[3] 79, 93, 94 💬
62MBX-8025 50 mg (Dose Escalation Period 1)----[1] 79 💬
63MBX-8025 50 mg or 100 mg (Dose Escalation Period 2)----[1] 79 💬
64MBX-8025 50 mg, 100 mg or 200 mg (Dose Escalation Period 3)----[1] 79 💬
65Mipomersen[1] Mipomersen---[1] 79 💬
66MK-0859----[1] 79 💬
67Nicotinic acid[1] Niacin[1] Niacin 💬--[1] 79 💬
68Omega-3[1] Omega-3 fatty acids---[7] 13, 46, 49, 66, 79, 96, 299 💬
69Omega-3 fatty acids[1] Omega-3 fatty acids---[2] 13, 79 💬
70Phospholipids[1] Omega-3 fatty acids---[1] 79 💬
71Placebo----[28] 3, 5, 6, 11, 13, 14, 37, 40, 46, 49, 50, 51, 53, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276 💬
72Praluent[1] Alirocumab[1] Alirocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
73Pravastatin[1] Pravastatin[1] Pravastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
74PRD7255830----[1] 79 💬
75PRD7255977----[1] 79 💬
76PRD7256003----[1] 79 💬
77Prednisone[1] Prednisone[1] Prednisone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
78R727----[1] 79 💬
79Recombinant Human Apolipoprotein----[1] 79 💬
80Recombinant Human Apolipoprotein A-I----[1] 79 💬
81Recombinant Human Apolipoprotein A-I/Phospholipids Complex[1] Omega-3 fatty acids---[1] 79 💬
82Recombinant human apolipoprotein a1----[1] 79 💬
83REGN1500----[1] 79 💬
84REGN1500 250 mg SC/15 mg/kg IV/450 mg SC----[1] 79 💬
85REGN7272----[1] 79 💬
86Repatha[1] Evolocumab[1] Evolocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
87Repatha (evolocumab)[1] Evolocumab[1] Evolocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
88Repatha 140 mg Solution for Injection in Pre-filled Pen[1] Evolocumab[1] Evolocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
89Repatha 140 mg soluzione per iniezione in penna preriempita.[1] Evolocumab[1] Evolocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
90Repatha 420 mg solution for injection in cartridge[1] Evolocumab[1] Evolocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
91Repatha 420 mg soluzione per iniezione in cartuccia[1] Evolocumab[1] Evolocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
92Rosuvastatin[1] Rosuvastatin[1] Rosuvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
93Rosuvastatin 20mg[1] Rosuvastatin[1] Rosuvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 79 💬
94ROSUVASTATIN CALCIUM[2] Calcium,
Rosuvastatin		[1] Rosuvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[4] 49, 79, 97, 299 💬
95SAR236553----[1] 79 💬
96Sfingomielina----[1] 79 💬
97SHR-1209----[1] 79 💬
98Simvastatin[1] Simvastatin[1] Simvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
99Single intravenous (IV) dose of human Low Density Lipoprotein Receptor (LDLR) Gene Therapy----[1] 79 💬
100Sphingomyelin----[1] 79 💬
101Standard of Care----[8] 6, 13, 49, 51, 63, 64, 79, 171 💬
102Statins----[2] 46, 79 💬
103TAK-475[1] TAK-475---[1] 79 💬
104Whole genome sequencing----[3] 6, 79, 172 💬
105ZD4522----[1] 79 💬