Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetate [1] Acetate---[41] 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
2 Alirocumab [2] ALIROCUMAB; Praluent[1] Alirocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
3 Anacetrapib [1] ANACETRAPIB[1] Anacetrapib 💬[1] CETP 💬[1] Cholesterol metabolism 💬[1] 79 💬
4 Atorvastatin [3] Atorvastatin; Atorvastatin calcium; Lipitor[1] Atorvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
5 Calcium [2] Calcio; Calcium---[27] 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
6 Cholestyramine [4] Cholestyramine; COLESTIRAMINA; COLESTYRAMINE; Questran---[3] 13, 79, 254 💬
7 Evinacumab [1] EVINACUMAB[1] Evinacumab 💬[1] ANGPTL3 💬[1] Cholesterol metabolism 💬[1] 79 💬
8 Evolocumab [2] EVOLOCUMAB; Repatha[1] Evolocumab 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[2] 79, 222 💬
9 Ezetimibe [2] Ezetimibe; Ezetrol[1] Ezetimibe 💬[1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260 💬
10 Fenofibrate [1] Fenofibrate[1] Fenofibrate 💬[1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
11 Fluvastatin [1] Fluvastatin[1] Fluvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 79, 218, 222 💬
12 Gemcabene [1] Gemcabene---[2] 79, 265 💬
13 Glycerin [2] Bee venom; Glycerol[1] Glycerin 💬--[5] 6, 13, 79, 316, 317 💬
14 Implitapide [1] Implitapide---[1] 79 💬
15 Inclisiran [3] ALN-PCSSC; Inclisiran; Leqvio[1] Inclisiran 💬[1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79 💬
16 Lapaquistat [1] Lapaquistat---[1] 79 💬
17 Lomitapide [2] Lojuxta; LOMITAPIDE[1] Lomitapide 💬[1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79 💬
18 Lovastatin [1] Lovastatin[1] Lovastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
19 Mipomersen [1] Mipomersen---[1] 79 💬
20 Niacin [2] Niacin; Nicotinic acid[1] Niacin 💬--[3] 6, 78, 79 💬
21 Omega-3 fatty acids [5] Omega-3; Omega-3 fatty acid; Omega-3 fatty acids; OMEGA-3-ACID TRIGLYCERIDES; Phospholipids---[8] 13, 46, 49, 53, 66, 79, 96, 299 💬
22 Pravastatin [2] Pravastatin; Pravastatin sodium[1] Pravastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
23 Prednisone [3] Prednisona; Prednisone; RAYOS[1] Prednisone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
24 Rosuvastatin [3] Crestor; Rosuvastatin; Rosuvastatin calcium[1] Rosuvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
25 Simvastatin [3] Simvastatin; Simvastatina; Simvastatine[1] Simvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
26 TAK-475 [1] TAK-475---[1] 79 💬