KEGG DRUG

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No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY	Disease ID
1	Ivacaftor+lumacaftor	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
2	LUMACAFTOR	[1] Lumacaftor	[1] Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
3	Lumacaftor / ivacaftor	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
4	Lumacaftor plus Ivacaftor	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
5	Lumacaftor Plus Ivacaftor Combination	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
6	Lumacaftor, Ivacaftor Drug Combination	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
7	Lumacaftor-ivacaftor	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
8	Lumacaftor-Ivacaftor treatment	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
9	Lumacaftor/Ivacaftor	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
10	Lumacaftor/ivacaftor 100mg/125mg tablets	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
11	Lumacaftor/ivacaftor 200mg/125mg	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
12	Lumacaftor/ivacaftor 200mg/125mg tablets	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
13	Lumacaftor/ivacaftor 200mg/83mg tablet	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
14	Orkambi: contains lumacaftor and ivacaftor	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor , Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
15	Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor	[4] Elexacaftor, Ivacaftor, Lumacaftor, Tezacaftor	[4] Ivacaftor , Lumacaftor , Tezacaftor , Elexacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬