Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Gastric acid secretion 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬 💬
2 Gastric acid secretion 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digoxin 💬 Digoxin [3]  8 , 46, 210 💬 💬
3 Gastric acid secretion 💬
[2] ATP4A, ATP4B 💬 Dexlansoprazole 💬 Dexlansoprazole [1] 98 💬 💬
4 Gastric acid secretion 💬
[2] ATP4A, ATP4B 💬 Esomeprazole 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 💬
5 Gastric acid secretion 💬
[2] ATP4A, ATP4B 💬 Lansoprazole 💬 Lansoprazole [7] 63, 71, 85, 98, 166, 222, 299 💬 💬
6 Gastric acid secretion 💬
[2] ATP4A, ATP4B 💬 Omeprazole 💬 Omeprazole [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 💬
7 Gastric acid secretion 💬
[2] ATP4A, ATP4B 💬 Pantoprazole 💬 Pantoprazole [2] 13, 65 💬 💬
8 Gastric acid secretion 💬
[2] ATP4A, ATP4B 💬 Rabeprazole 💬 Rabeprazole [2]  2 , 51 💬 💬
9 Gastric acid secretion 💬
[2] ATP4A, ATP4B 💬 Vonoprazan 💬 Vonoprazan [2] 63, 98 💬 💬
10 Gastric acid secretion 💬
[1] CA2 💬 Acetazolamide 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬 💬
11 Gastric acid secretion 💬
[1] CA2 💬 Dichlorphenamide 💬 Diclofenamide [1] 114 💬 💬
12 Gastric acid secretion 💬
[1] CA2 💬 Dorzolamide 💬 Dorzolamide [1] 90 💬 💬
13 Gastric acid secretion 💬
[1] CA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬 💬
14 Gastric acid secretion 💬
[1] CCKBR 💬 Proglumide 💬 Proglumide [1] 298 💬 💬
15 Gastric acid secretion 💬
[1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬 💬
16 Gastric acid secretion 💬
[1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬 💬
17 Gastric acid secretion 💬
[1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬 💬
18 Gastric acid secretion 💬
[1] CFTR 💬 Ivacaftor 💬 Ivacaftor [1] 299 💬 💬
19 Gastric acid secretion 💬
[1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬 💬
20 Gastric acid secretion 💬
[1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬 💬
21 Gastric acid secretion 💬
[1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬 💬
22 Gastric acid secretion 💬
[1] CHRM3 💬 Blarcamesine 💬 Blarcamesine [1] 156 💬 💬
23 Gastric acid secretion 💬
[1] CHRM3 💬 Cevimeline 💬 Cevimeline [1] 53 💬 💬
24 Gastric acid secretion 💬
[1] CHRM3 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬 💬
25 Gastric acid secretion 💬
[1] CHRM3 💬 Darifenacin 💬 Darifenacin [2]  6 , 13 💬 💬
26 Gastric acid secretion 💬
[1] CHRM3 💬 Fesoterodine 💬 Fesoterodine [1]  6  💬 💬
27 Gastric acid secretion 💬
[1] CHRM3 💬 Oxybutynin 💬 Oxybutynin [3]  6 , 13, 53 💬 💬
28 Gastric acid secretion 💬
[1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬 💬
29 Gastric acid secretion 💬
[1] CHRM3 💬 Propiverine 💬 Propiverine [1] 226 💬 💬
30 Gastric acid secretion 💬
[1] CHRM3 💬 Scopolamine 💬 Scopolamine [1]  2  💬 💬
31 Gastric acid secretion 💬
[1] CHRM3 💬 Solifenacin 💬 Solifenacin [3]  6 , 13, 53 💬 💬
32 Gastric acid secretion 💬
[1] CHRM3 💬 Tolterodine 💬 Tolterodine [2] 17, 53 💬 💬
33 Gastric acid secretion 💬
[1] CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl [2]  5 ,  6  💬 💬
34 Gastric acid secretion 💬
[1] CHRM3 💬 Tropicamide 💬 Tropicamide [1]  6  💬 💬
35 Gastric acid secretion 💬
[1] HRH2 💬 Cimetidine 💬 Cimetidine [2]  2 , 254 💬 💬
36 Gastric acid secretion 💬
[1] HRH2 💬 Famotidine 💬 Famotidine [6]  6 , 46, 61, 86, 98, 107 💬 💬
37 Gastric acid secretion 💬
[1] HRH2 💬 Ranitidine 💬 Ranitidine [2] 13, 65 💬 💬
38 Gastric acid secretion 💬
[1] KCNQ1 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬 💬
39 Gastric acid secretion 💬
[1] KCNQ1 💬 Ezogabine 💬 Ezogabine [2]  2 , 144 💬 💬
40 Gastric acid secretion 💬
[1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬 💬
41 Gastric acid secretion 💬
[1] SSTR2 💬 Octreotide 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬 💬
42 Gastric acid secretion 💬
[1] SSTR2 💬 Pasireotide 💬 Pasireotide [3] 67, 74, 75 💬 💬
43 Gastric acid secretion 💬
[1] SSTR2 💬 Somatostatin 💬 Somatostatin [2] 67, 78 💬 💬