KEGG DRUG

Search results

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY	Disease ID
1	150-mg IVACAFTOR (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
2	150mg IVACAFTOR (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
3	75-mg IVACAFTOR (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
4	CF patients with a G551D mutation and treated with Ivacaftor (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
5	Deuterated Ivacaftor (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
6	Elexacaftor / Ivacaftor / Tezacaftor (D09916)	[3] Elexacaftor, Ivacaftor, Tezacaftor	[3] Ivacaftor (D09916), Tezacaftor , Elexacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
7	Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening (D09916)	[3] Elexacaftor, Ivacaftor, Tezacaftor	[3] Ivacaftor (D09916), Tezacaftor , Elexacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
8	Elexacaftor-tezacaftor-ivacaftor exposure (D09916)	[3] Elexacaftor, Ivacaftor, Tezacaftor	[3] Ivacaftor (D09916), Tezacaftor , Elexacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
9	Elexacaftor/tezacaftor/ivacaftor (D09916)	[3] Elexacaftor, Ivacaftor, Tezacaftor	[3] Ivacaftor (D09916), Tezacaftor , Elexacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
10	IVACAFTOR (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
11	Ivacaftor (proposed INN) (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
12	Ivacaftor 125mg tablet (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
13	Ivacaftor 150 mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
14	Ivacaftor 150 mg or 250 mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
15	Ivacaftor 25 mg/75 mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
16	IVACAFTOR 59,5mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
17	IVACAFTOR 59.5mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
18	Ivacaftor 75 mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
19	Ivacaftor 75 mg/150 mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
20	IVACAFTOR 75mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
21	Ivacaftor Exposed (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
22	Ivacaftor or elexacaftor/tezacaftor/ivacaftor (D09916)	[3] Elexacaftor, Ivacaftor, Tezacaftor	[3] Ivacaftor (D09916), Tezacaftor , Elexacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
23	Ivacaftor+lumacaftor (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
24	Ivacaftor/Ataluren (D09916)	[2] Ataluren, Ivacaftor	[2] Ataluren , Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
25	Ivacaftor/Kalydeco (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
26	Ivacaftor/Trikafta (D09916)	[3] Elexacaftor, Ivacaftor, Tezacaftor	[3] Ivacaftor (D09916), Tezacaftor , Elexacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
27	Lumacaftor / ivacaftor (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
28	Lumacaftor plus Ivacaftor (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
29	Lumacaftor Plus Ivacaftor Combination (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
30	Lumacaftor, Ivacaftor Drug Combination (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
31	Lumacaftor-ivacaftor (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
32	Lumacaftor-Ivacaftor treatment (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
33	Lumacaftor/Ivacaftor (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
34	Lumacaftor/ivacaftor 100mg/125mg tablets (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
35	Lumacaftor/ivacaftor 200mg/125mg (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
36	Lumacaftor/ivacaftor 200mg/125mg tablets (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
37	Lumacaftor/ivacaftor 200mg/83mg tablet (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
38	Orkambi: contains lumacaftor and ivacaftor (D09916)	[2] Ivacaftor, Lumacaftor	[2] Ivacaftor (D09916), Lumacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
39	Tezacaftor/Ivacaftor (D09916)	[2] Ivacaftor, Tezacaftor	[2] Ivacaftor (D09916), Tezacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
40	Tezacaftor/Ivacaftor + Ivacaftor (D09916)	[2] Ivacaftor, Tezacaftor	[2] Ivacaftor (D09916), Tezacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
41	Tezacaftor/Ivacaftor 100mg/150mg (D09916)	[2] Ivacaftor, Tezacaftor	[2] Ivacaftor (D09916), Tezacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
42	Tezacaftor/Ivacaftor/100mg/150mg (D09916)	[2] Ivacaftor, Tezacaftor	[2] Ivacaftor (D09916), Tezacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
43	Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor (D09916)	[4] Elexacaftor, Ivacaftor, Lumacaftor, Tezacaftor	[4] Ivacaftor (D09916), Lumacaftor , Tezacaftor , Elexacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
44	VX-659/Tezacaftor/Ivacaftor (D09916)	[3] Ivacaftor, Tezacaftor, VX-659	[2] Ivacaftor (D09916), Tezacaftor 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
45	VX-661 Plus Ivacaftor Combination (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
46	VX-661/Ivacaftor (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
47	VX-661/ivacaftor (VX-770) 100mg/150 mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
48	VX-661/ivacaftor 100 mg/ 150 mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
49	VX-661/ivacaftor 100mg/150 mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
50	VX-661/ivacaftor 100mg/150mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬
51	VX-661/ivacaftor 50 mg/ 75 mg (D09916)	[1] Ivacaftor	[1] Ivacaftor (D09916) 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299 💬