Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Elexacaftor / Ivacaftor / Tezacaftor
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
2Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
3Elexacaftor-tezacaftor-ivacaftor exposure
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
4Elexacaftor/tezacaftor/ivacaftor
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
5Ivacaftor or elexacaftor/tezacaftor/ivacaftor
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
6TEZACAFTOR
(D11041)		[1] Tezacaftor[1] Tezacaftor (D11041) 💬[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
7Tezacaftor (TEZ)
(D11041)		[1] Tezacaftor[1] Tezacaftor (D11041) 💬[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
8Tezacaftor/Ivacaftor
(D11041)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor ,
Tezacaftor (D11041) 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
9Tezacaftor/Ivacaftor + Ivacaftor
(D11041)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor ,
Tezacaftor (D11041) 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
10Tezacaftor/Ivacaftor 100mg/150mg
(D11041)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor ,
Tezacaftor (D11041) 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
11Tezacaftor/Ivacaftor/100mg/150mg
(D11041)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor ,
Tezacaftor (D11041) 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
12Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor
(D11041)		[4] Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor		[4] Ivacaftor ,
Lumacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
13VX-121/tezacaftor/deutivacaftor
(D11041)		[2] Deutivacaftor,
Tezacaftor		[2] Tezacaftor (D11041),
Deutivacaftor 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
14VX-659/Tezacaftor/Ivacaftor
(D11041)		[3] Ivacaftor,
Tezacaftor,
VX-659		[2] Ivacaftor ,
Tezacaftor (D11041) 💬		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬