88. 慢性血栓塞栓性肺高血圧症 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 157 / 薬物数 : 107 - (DrugBank : 22) / 標的遺伝子数 : 14 - 標的パスウェイ数 : 54
薬物ごとの開発者（Primary Sponsor）、臨床試験情報（抜粋）です。
ACT-064992
Actelion Pharmaceuticals Ltd
2021 Phase 3 EUCTR2017-003934-10-PL Belarus;Belgium;France;Germany;Poland;Russian Federation;Turkey;Ukraine;
Actelion Pharmaceuticals Ltd.
2015 Phase 2 EUCTR2013-003457-25-LT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2015 Phase 2 EUCTR2013-002950-56-LT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2015 - EUCTR2013-003457-25-NL Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-HU Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-GB Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-FR Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-DE Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-CZ Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-BE Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-AT Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-NL Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-HU Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-GB Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-DE Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-CZ Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-BE Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-AT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
ACT-293987
ACTELION PHARMACEUTICALS LTD
2019 Phase 3 EUCTR2018-002823-41-IT Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Democratic People's Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
Actelion Pharmaceuticals Ltd
2019 Phase 3 EUCTR2018-002823-41-PT Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-NL Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-HU Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-GB Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-DK Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-DE Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-CZ Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-BG Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-BE Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-AT Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
Adempas
Bayer AG
2009 Phase 3 EUCTR2008-003539-19-PT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer AG
2013 Phase 3 EUCTR2012-002104-40-PT Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-GB Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2013 Phase 3 EUCTR2012-002104-40-GB Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-002104-40-CZ Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-NL Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2010 Phase 3 EUCTR2008-003539-19-DK Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-CZ Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-BE Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-AT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Adempas (Riociguat, BAY63-2521)
Bayer
2013 - NCT01784562 Austria;Belgium;Canada;Colombia;Czech Republic;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
Adempas (active agent riociguat)
Thoraxklinik Heidelberg gGmbH
2021 Phase 4 EUCTR2020-005462-34-DE Germany;
Adempas®
International CTEPH Association (ICA)
2018 Phase 2 EUCTR2017-001121-40-GB France;Germany;United Kingdom;United States;
2018 Phase 2 EUCTR2017-001121-40-FR France;Germany;United Kingdom;United States;
2018 Phase 2 EUCTR2017-001121-40-DE France;Germany;United Kingdom;United States;
Ambrisentan
GlaxoSmithKline
2014 Phase 3 NCT01894022 Argentina;Austria;Canada;China;Czech Republic;Czechia;Germany;Israel;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;United Kingdom;United States;
2013 Phase 3 NCT01884675 Argentina;Austria;Canada;China;Czech Republic;Germany;Israel;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;United Kingdom;United States;
GlaxoSmithKline Research & Developement Ltd
2014 Phase 3 EUCTR2012-001646-18-IT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001646-18-NL Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-GB Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-DE Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-CZ Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-AT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
GlaxoSmithKline, S.A.
2013 - EUCTR2012-001646-18-ES Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States;
Ammonia
Ottawa Heart Institute Research Corporation
2014 Phase 2 NCT02094001 Canada;
Atorvastatin
Tongji Hospital of Tongji University
2008 - ChiCTR-TNRC-08000263 China;
BAY 63-2521
Bayer HealthCare AG
2008 Phase 3 EUCTR2007-000072-16-IT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2006 Phase 1;Phase 2 EUCTR2006-003520-10-DE Germany;
International CTEPH Association (ICA)
2018 Phase 2 EUCTR2017-001121-40-GB France;Germany;United Kingdom;United States;
2018 Phase 2 EUCTR2017-001121-40-FR France;Germany;United Kingdom;United States;
2018 Phase 2 EUCTR2017-001121-40-DE France;Germany;United Kingdom;United States;
BAY 63-2521 IR coated tablet
Bayer HealthCare AG
2013 Phase 3 EUCTR2012-002104-40-GB Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
BAY 63-2521 IR tablet
Bayer AG
2013 Phase 3 EUCTR2012-002104-40-PT Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-002104-40-DE Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2013 Phase 3 EUCTR2012-002104-40-SE Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-002104-40-CZ Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-002104-40-BE Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-NL Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-IT Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-ES Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-DK Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-AT Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
BAY 63-2521 coated tablets
Bayer AG
2009 Phase 3 EUCTR2008-003539-19-PT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer AG
2009 Phase 3 EUCTR2008-003539-19-GB Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2010 Phase 3 EUCTR2008-003539-19-DK Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-CZ Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-BE Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-AT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
BAY 63-2521 tablets
Bayer AG
2010 Phase 3 EUCTR2008-003539-19-SK Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2010 - EUCTR2007-000072-16-DK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-SK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-BE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-AT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-PT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-IE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-CZ Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2008-003539-19-DE Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2008 Phase 3 EUCTR2007-000072-16-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2007-000072-16-ES Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
- - EUCTR2007-000072-16-DE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
2009 Phase 3 EUCTR2008-003539-19-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2008-003539-19-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2008-003539-19-IE Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom;
Bayer HealthCare AG, D-51368 Leverkusen
2009 Phase 3 EUCTR2007-000072-16-GB Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
BAY1237592
Bayer
2019 Phase 1 NCT03754660 Austria;Czechia;Germany;Poland;
BPA
Fukuda Keiichi
2016 - JPRN-jRCTs031180239 Japan;
Fuwai Hospital, Chinese Academy of Medical Sciences
2021 Phase 0 ChiCTR2100052570 China;
Keio University School of Medicine
2016 - JPRN-UMIN000019549 Japan;
Shanghai Pulmonary Hospital
2021 Phase 0 ChiCTR2000032403 China;
Shimokawahara Hiroto
2021 Phase 2 JPRN-jRCTs041200052 Japan;
Tatsuguchi Mariko
2021 - JPRN-jRCT1041200111 Japan;
The First Affiliated Hospital of Guangzhou Medical University
2019 - ChiCTR2000034995 China;
Ballon Pulmonary Angioplasty
Medical University of Vienna
2017 - NCT03074539 Austria;
Balloon Pulmonary Angioplasty (BPA)
Assistance Publique - Hôpitaux de Paris
2016 - NCT02634203 France;
Bosentan
ACTELION PHARMACEUTICALS ITALIA
2006 - EUCTR2005-002900-40-IT Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-IT Germany;Italy;Spain;United Kingdom;
Actelion
2006 Phase 3 NCT00319111 Australia;Austria;Belgium;Canada;Czech Republic;France;Germany;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
2005 Phase 3 NCT00313222 Australia;Austria;Belgium;Canada;Czech Republic;France;Germany;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
Bosentan monohydrate
Actelion Pharmaceuticals Ltd.
2006 Phase 3 EUCTR2005-002900-40-GB Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-CZ Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-BE Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-GB Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-CZ Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-002900-40-AT Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-DE Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-AT Austria;Germany;Italy;Spain;United Kingdom;
Catheter directed therapy
University of Arizona
2021 - NCT05133713 United States;
Edoxaban
Abe Kohtaro
2021 Phase 3 JPRN-jRCT2071200098 Japan;
Division of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine
2016 Phase 4 JPRN-UMIN000018520 Japan;
Kyushu University
2021 Phase 3 NCT04730037 Japan;
GSK1325760
GlaxoSmithKline Research & Developement Ltd
2014 Phase 3 EUCTR2012-001646-18-IT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001646-18-NL Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-GB Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-DE Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-CZ Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-AT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
GlaxoSmithKline Research & Developement Ltd
2014 Phase 3 EUCTR2012-001642-17-IT Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-001642-17-GB Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 Phase 3 EUCTR2012-001642-17-CZ Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001642-17-NL Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001642-17-DE Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Italy;Japan;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;Turkey;United Kingdom;United States;
2013 - EUCTR2012-001642-17-AT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
GlaxoSmithKline, S.A.
2013 - EUCTR2012-001646-18-ES Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States;
2013 - EUCTR2012-001642-17-ES Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States;
Imatinib mesilate
Imperial College London
2020 Phase 2 EUCTR2020-001157-48-GB United Kingdom;
Iodine
University of Sheffield
2019 - NCT03806907 -
JNJ-67896062 / ACT-064992
ACTELION PHARMACEUTICALS LTD
2020 Phase 3 EUCTR2019-004131-24-IT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
ACTELION Pharmaceuticals Ltd.
2020 Phase 3 EUCTR2019-004131-24-PL Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-LT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-HU Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-GB Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-ES Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-DE Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
JNJ-67896062/ ACT-064992
ACTELION PHARMACEUTICALS LTD
2020 Phase 3 EUCTR2019-004131-24-IT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
Long term oxygen therapy
University of Zurich
2013 Phase 3 NCT01884012 Switzerland;
MACITENTAN COMPRESSE
ACTELION PHARMACEUTICALS LTD
2020 Phase 3 EUCTR2019-004131-24-IT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
Macitentan
Actelion
2020 Phase 3 NCT04271475 Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 NCT03809650 Japan;
2018 Phase 3 NCT03422328 Belarus;Belgium;France;Poland;Russian Federation;Ukraine;
2015 Phase 2 NCT02060721 Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Italy;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 NCT02021292 Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Italy;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam;
Assistance Publique - Hôpitaux de Paris
2021 Phase 2/Phase 3 NCT04780932 France;
Nakano Masayoshi
2021 Phase 3 JPRN-jRCT2051200150 Germany;Hungary;Japan;South Korea;USA;
Macitentan tablets
ACTELION Pharmaceuticals Ltd.
2020 Phase 3 EUCTR2019-004131-24-PL Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-LT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-HU Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-GB Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-ES Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-DE Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
Methyl 4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo [3,4-b]pyridine-3-yl]-5-pyrimidinyl(methyl)carb
Bayer AG
2010 Phase 3 EUCTR2008-003539-19-SK Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2010 - EUCTR2007-000072-16-DK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-SK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-BE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-AT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-PT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-IE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-CZ Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2008-003539-19-DE Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2008 Phase 3 EUCTR2007-000072-16-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2007-000072-16-ES Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
- - EUCTR2007-000072-16-DE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
2009 Phase 3 EUCTR2008-003539-19-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2008-003539-19-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2008-003539-19-IE Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom;
Bayer HealthCare AG, D-51368 Leverkusen
2009 Phase 3 EUCTR2007-000072-16-GB Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Methyl [4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]meth
Bayer HealthCare AG
2006 Phase 1;Phase 2 EUCTR2006-003520-10-DE Germany;
MultiHance
Brigham and Women's Hospital
2013 Phase 2 NCT01953965 United States;
N-acetyl cysteine
Instituto Nacional de Cardiologia Ignacio Chavez
2019 - NCT04081012 Mexico;
NS-304
NIPPON SHINYAKU CO., LTD.
2013 Phase 2 JPRN-JapicCTI-132159 -
NIPPON SHINYAKU CO., LTD. / Actelion Pharmaceuticals Japan Ltd.
2010 Phase 2 JPRN-JapicCTI-111667 -
2010 Phase 2 JPRN-JapicCTI-111666 -
NS-304 Placebo
Nippon Shinyaku Co., Ltd.
2016 Phase 3 JPRN-JapicCTI-163279 Japan;
Opsumit
Actelion Pharmaceuticals Ltd
2021 Phase 3 EUCTR2017-003934-10-PL Belarus;Belgium;France;Germany;Poland;Russian Federation;Turkey;Ukraine;
Actelion Pharmaceuticals Ltd.
2015 Phase 2 EUCTR2013-003457-25-LT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2015 Phase 2 EUCTR2013-002950-56-LT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2015 - EUCTR2013-003457-25-NL Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-HU Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-GB Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-DE Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-BE Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-AT Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-DE Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-CZ Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-BE Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-AT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
Opsumit®
ACTELION PHARMACEUTICALS LTD
2020 Phase 3 EUCTR2019-004131-24-IT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
ACTELION Pharmaceuticals Ltd.
2020 Phase 3 EUCTR2019-004131-24-PL Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-LT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-HU Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-GB Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-ES Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-DE Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
Actelion Pharmaceuticals Ltd.
2014 Phase 2 EUCTR2013-003457-25-FR Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-CZ Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-NL Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-HU Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-GB Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States;
Oxygen
Department of Cardiology, Hospital Organization Okayama Medical Center
2015 - JPRN-UMIN000026882 Japan;
Heidelberg University
2019 Phase 2 NCT04207593 Germany;
University of Zurich
2015 - NCT02558582 Switzerland;
Oxygen, liquid
Thoraxklinik-Heidelberg gGmbH
2019 Phase 2 EUCTR2018-001387-39-DE Germany;
Placebo
NIPPON SHINYAKU CO., LTD. / Actelion Pharmaceuticals Japan Ltd.
2010 Phase 2 JPRN-JapicCTI-111667 -
Pulmonary Endarteriectomy
Medical University of Vienna
2017 - NCT03074539 Austria;
Pulmonary endarterectomy
International CTEPH Association
2018 Phase 2 NCT03273257 France;Germany;United Kingdom;United States;
Remodulin (R)
MRN-Medical Research Network GmbH
2009 Phase 3 EUCTR2008-006441-10-SK Austria;Czech Republic;Germany;Slovakia;
Remodulin 10mg/ml 20ml
MRN-Medical Research Network GmbH
2010 - EUCTR2008-006441-10-DE Austria;Czech Republic;Germany;
Remodulin 1mg/ml 20ml
MRN-Medical Research Network GmbH
2010 - EUCTR2008-006441-10-DE Austria;Czech Republic;Germany;
Remodulin 2.5mg/ml 20ml
MRN-Medical Research Network GmbH
2010 - EUCTR2008-006441-10-DE Austria;Czech Republic;Germany;
Remodulin 5mg/ml 20ml
MRN-Medical Research Network GmbH
2010 - EUCTR2008-006441-10-DE Austria;Czech Republic;Germany;
Riociguat
Adachi Shiro
2021 - JPRN-jRCT1041210122 Japan;
Assistance Publique - Hôpitaux de Paris
2016 - NCT02634203 France;
Bayer AG
2009 Phase 3 EUCTR2008-003539-19-PT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer AG
2010 Phase 3 EUCTR2008-003539-19-SK Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2010 - EUCTR2007-000072-16-DK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2008-003539-19-AT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2007-000072-16-SK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-BE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-AT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-PT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-IE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-CZ Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2008-003539-19-DE Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2008 Phase 3 EUCTR2007-000072-16-IT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2007-000072-16-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2007-000072-16-ES Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2006 Phase 1;Phase 2 EUCTR2006-003520-10-DE Germany;
- - EUCTR2007-000072-16-DE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
2009 Phase 3 EUCTR2008-003539-19-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2008-003539-19-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2008-003539-19-IE Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom;
Bayer HealthCare AG, D-51368 Leverkusen
2009 Phase 3 EUCTR2007-000072-16-GB Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Fukuda Keiichi
2016 - JPRN-jRCTs031180239 Japan;
Heidelberg University
2021 Phase 4 NCT04954742 Germany;
International CTEPH Association
2018 Phase 2 NCT03273257 France;Germany;United Kingdom;United States;
Keio University School of Medicine
2016 - JPRN-UMIN000019549 Japan;
Medical University of Vienna
2017 - NCT03074539 Austria;
Shanghai Pulmonary Hospital
2021 Phase 0 ChiCTR2000032403 China;
Shimokawahara Hiroto
2021 Phase 2 JPRN-jRCTs041200052 Japan;
Riociguat (ADEMPAS, BAY63-2521)
Bayer
2014 - NCT02117791 Japan;
Riociguat (Adempas, BAY63-2521)
Bayer
2015 - NCT02545465 Belgium;Canada;Colombia;Denmark;Germany;Japan;Sweden;Turkey;United Kingdom;
2009 Phase 3 NCT00910429 Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 NCT00855465 Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Riociguat Oral Tablet
National Hospital Organization Okayama Medical Center
2020 Phase 2 NCT04600492 Japan;
Ro 47-0203
Actelion Pharmaceuticals Ltd.
2006 Phase 3 EUCTR2005-002900-40-GB Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-DE Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-CZ Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-BE Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-GB Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-CZ Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-002900-40-AT Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-DE Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-AT Austria;Germany;Italy;Spain;United Kingdom;
Sauerstoff
Thoraxklinik-Heidelberg gGmbH
2019 Phase 2 EUCTR2018-001387-39-DE Germany;
Selexipag
Actelion
2019 Phase 3 NCT03689244 Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czechia;Denmark;Germany;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
Adachi Shiro
2021 - JPRN-jRCT1041210122 Japan;
NIPPON SHINYAKU CO., LTD.
2013 Phase 2 JPRN-JapicCTI-132159 -
NIPPON SHINYAKU CO., LTD. / Actelion Pharmaceuticals Japan Ltd.
2010 Phase 2 JPRN-JapicCTI-111667 -
2010 Phase 2 JPRN-JapicCTI-111666 -
Nippon Shinyaku Co., Ltd.
2016 Phase 3 JPRN-JapicCTI-163279 Japan;
Supplemental oxygen via a mask
University of Zurich
2012 Phase 2 NCT01748474 Switzerland;
Systemic anticoagulation
University of Arizona
2021 - NCT05133713 United States;
TRACLEER 125MG 56CPR RIV.
ACTELION PHARMACEUTICALS ITALIA
2005 - EUCTR2005-001965-33-IT Germany;Italy;Spain;United Kingdom;
TRACLEER*56CPR RIV
ACTELION PHARMACEUTICALS ITALIA
2006 - EUCTR2005-002900-40-IT Czech Republic;Germany;Italy;Spain;United Kingdom;
TREPROSTINIL SODIUM
MRN-Medical Research Network GmbH
2010 - EUCTR2008-006441-10-DE Austria;Czech Republic;Germany;
Thrombin
National and Kapodistrian University of Athens
2015 - NCT03195543 Greece;
Tracleer
Actelion Pharmaceuticals Ltd.
2006 Phase 3 EUCTR2005-002900-40-GB Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-CZ Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-GB Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-CZ Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-002900-40-AT Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-DE Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-AT Austria;Germany;Italy;Spain;United Kingdom;
Treprostinil sodium
SciPharm SàRL
2009 Phase 3 NCT01416636 Austria;Czech Republic;Czechia;Germany;Poland;
Uptravi
ACTELION PHARMACEUTICALS LTD
2019 Phase 3 EUCTR2018-002823-41-IT Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Democratic People's Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
Actelion Pharmaceuticals Ltd
2019 Phase 3 EUCTR2018-002823-41-PT Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-NL Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-HU Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-GB Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-DK Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-DE Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-CZ Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-BG Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-BE Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-AT Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
Volibris
GlaxoSmithKline Research & Developement Ltd
2014 Phase 3 EUCTR2012-001646-18-IT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001646-18-NL Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-GB Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-DE Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-CZ Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-AT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
GlaxoSmithKline Research & Developement Ltd
2014 Phase 3 EUCTR2012-001642-17-IT Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-001642-17-GB Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 Phase 3 EUCTR2012-001642-17-CZ Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001642-17-NL Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001642-17-DE Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Italy;Japan;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;Turkey;United Kingdom;United States;
2013 - EUCTR2012-001642-17-AT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
GlaxoSmithKline, S.A.
2013 - EUCTR2012-001646-18-ES Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States;
2013 - EUCTR2012-001642-17-ES Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States;
Warfarin
Abe Kohtaro
2021 Phase 3 JPRN-jRCT2071200098 Japan;
Division of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine
2016 Phase 4 JPRN-UMIN000018520 Japan;
Warfarin Potassium
Kyushu University
2021 Phase 3 NCT04730037 Japan;
[18F]Fluoro-2-deoxy-2-D-glucose
Brigham and Women's Hospital
2013 Phase 2 NCT01953965 United States;
Actelion Pharmaceuticals Ltd
2021 Phase 3 EUCTR2017-003934-10-PL Belarus;Belgium;France;Germany;Poland;Russian Federation;Turkey;Ukraine;
Actelion Pharmaceuticals Ltd.
2015 Phase 2 EUCTR2013-003457-25-LT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2015 Phase 2 EUCTR2013-002950-56-LT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2015 - EUCTR2013-003457-25-NL Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-HU Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-GB Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-FR Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-DE Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-CZ Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-BE Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-AT Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-NL Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-HU Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-GB Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-DE Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-CZ Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-BE Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-AT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
ACT-293987
ACTELION PHARMACEUTICALS LTD
2019 Phase 3 EUCTR2018-002823-41-IT Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Democratic People's Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
Actelion Pharmaceuticals Ltd
2019 Phase 3 EUCTR2018-002823-41-PT Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-NL Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-HU Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-GB Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-DK Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-DE Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-CZ Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-BG Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-BE Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-AT Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
Adempas
Bayer AG
2009 Phase 3 EUCTR2008-003539-19-PT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer AG
2013 Phase 3 EUCTR2012-002104-40-PT Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-GB Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2013 Phase 3 EUCTR2012-002104-40-GB Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-002104-40-CZ Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-NL Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2010 Phase 3 EUCTR2008-003539-19-DK Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-CZ Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-BE Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-AT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Adempas (Riociguat, BAY63-2521)
Bayer
2013 - NCT01784562 Austria;Belgium;Canada;Colombia;Czech Republic;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
Adempas (active agent riociguat)
Thoraxklinik Heidelberg gGmbH
2021 Phase 4 EUCTR2020-005462-34-DE Germany;
Adempas®
International CTEPH Association (ICA)
2018 Phase 2 EUCTR2017-001121-40-GB France;Germany;United Kingdom;United States;
2018 Phase 2 EUCTR2017-001121-40-FR France;Germany;United Kingdom;United States;
2018 Phase 2 EUCTR2017-001121-40-DE France;Germany;United Kingdom;United States;
Ambrisentan
GlaxoSmithKline
2014 Phase 3 NCT01894022 Argentina;Austria;Canada;China;Czech Republic;Czechia;Germany;Israel;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;United Kingdom;United States;
2013 Phase 3 NCT01884675 Argentina;Austria;Canada;China;Czech Republic;Germany;Israel;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;United Kingdom;United States;
GlaxoSmithKline Research & Developement Ltd
2014 Phase 3 EUCTR2012-001646-18-IT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001646-18-NL Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-GB Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-DE Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-CZ Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-AT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
GlaxoSmithKline, S.A.
2013 - EUCTR2012-001646-18-ES Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States;
Ammonia
Ottawa Heart Institute Research Corporation
2014 Phase 2 NCT02094001 Canada;
Atorvastatin
Tongji Hospital of Tongji University
2008 - ChiCTR-TNRC-08000263 China;
BAY 63-2521
Bayer HealthCare AG
2008 Phase 3 EUCTR2007-000072-16-IT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2006 Phase 1;Phase 2 EUCTR2006-003520-10-DE Germany;
International CTEPH Association (ICA)
2018 Phase 2 EUCTR2017-001121-40-GB France;Germany;United Kingdom;United States;
2018 Phase 2 EUCTR2017-001121-40-FR France;Germany;United Kingdom;United States;
2018 Phase 2 EUCTR2017-001121-40-DE France;Germany;United Kingdom;United States;
BAY 63-2521 IR coated tablet
Bayer HealthCare AG
2013 Phase 3 EUCTR2012-002104-40-GB Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
BAY 63-2521 IR tablet
Bayer AG
2013 Phase 3 EUCTR2012-002104-40-PT Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-002104-40-DE Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2013 Phase 3 EUCTR2012-002104-40-SE Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-002104-40-CZ Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-002104-40-BE Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-NL Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-IT Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-ES Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-DK Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
2013 - EUCTR2012-002104-40-AT Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
BAY 63-2521 coated tablets
Bayer AG
2009 Phase 3 EUCTR2008-003539-19-PT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer AG
2009 Phase 3 EUCTR2008-003539-19-GB Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2010 Phase 3 EUCTR2008-003539-19-DK Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-CZ Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-BE Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2008-003539-19-AT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
BAY 63-2521 tablets
Bayer AG
2010 Phase 3 EUCTR2008-003539-19-SK Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2010 - EUCTR2007-000072-16-DK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-SK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-BE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-AT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-PT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-IE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-CZ Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2008-003539-19-DE Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2008 Phase 3 EUCTR2007-000072-16-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2007-000072-16-ES Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
- - EUCTR2007-000072-16-DE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
2009 Phase 3 EUCTR2008-003539-19-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2008-003539-19-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2008-003539-19-IE Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom;
Bayer HealthCare AG, D-51368 Leverkusen
2009 Phase 3 EUCTR2007-000072-16-GB Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
BAY1237592
Bayer
2019 Phase 1 NCT03754660 Austria;Czechia;Germany;Poland;
BPA
Fukuda Keiichi
2016 - JPRN-jRCTs031180239 Japan;
Fuwai Hospital, Chinese Academy of Medical Sciences
2021 Phase 0 ChiCTR2100052570 China;
Keio University School of Medicine
2016 - JPRN-UMIN000019549 Japan;
Shanghai Pulmonary Hospital
2021 Phase 0 ChiCTR2000032403 China;
Shimokawahara Hiroto
2021 Phase 2 JPRN-jRCTs041200052 Japan;
Tatsuguchi Mariko
2021 - JPRN-jRCT1041200111 Japan;
The First Affiliated Hospital of Guangzhou Medical University
2019 - ChiCTR2000034995 China;
Ballon Pulmonary Angioplasty
Medical University of Vienna
2017 - NCT03074539 Austria;
Balloon Pulmonary Angioplasty (BPA)
Assistance Publique - Hôpitaux de Paris
2016 - NCT02634203 France;
Bosentan
ACTELION PHARMACEUTICALS ITALIA
2006 - EUCTR2005-002900-40-IT Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-IT Germany;Italy;Spain;United Kingdom;
Actelion
2006 Phase 3 NCT00319111 Australia;Austria;Belgium;Canada;Czech Republic;France;Germany;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
2005 Phase 3 NCT00313222 Australia;Austria;Belgium;Canada;Czech Republic;France;Germany;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
Bosentan monohydrate
Actelion Pharmaceuticals Ltd.
2006 Phase 3 EUCTR2005-002900-40-GB Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-CZ Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-BE Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-GB Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-CZ Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-002900-40-AT Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-DE Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-AT Austria;Germany;Italy;Spain;United Kingdom;
Catheter directed therapy
University of Arizona
2021 - NCT05133713 United States;
Edoxaban
Abe Kohtaro
2021 Phase 3 JPRN-jRCT2071200098 Japan;
Division of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine
2016 Phase 4 JPRN-UMIN000018520 Japan;
Kyushu University
2021 Phase 3 NCT04730037 Japan;
GSK1325760
GlaxoSmithKline Research & Developement Ltd
2014 Phase 3 EUCTR2012-001646-18-IT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001646-18-NL Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-GB Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-DE Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-CZ Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-AT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
GlaxoSmithKline Research & Developement Ltd
2014 Phase 3 EUCTR2012-001642-17-IT Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-001642-17-GB Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 Phase 3 EUCTR2012-001642-17-CZ Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001642-17-NL Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001642-17-DE Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Italy;Japan;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;Turkey;United Kingdom;United States;
2013 - EUCTR2012-001642-17-AT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
GlaxoSmithKline, S.A.
2013 - EUCTR2012-001646-18-ES Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States;
2013 - EUCTR2012-001642-17-ES Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States;
Imatinib mesilate
Imperial College London
2020 Phase 2 EUCTR2020-001157-48-GB United Kingdom;
Iodine
University of Sheffield
2019 - NCT03806907 -
JNJ-67896062 / ACT-064992
ACTELION PHARMACEUTICALS LTD
2020 Phase 3 EUCTR2019-004131-24-IT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
ACTELION Pharmaceuticals Ltd.
2020 Phase 3 EUCTR2019-004131-24-PL Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-LT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-HU Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-GB Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-ES Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-DE Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
JNJ-67896062/ ACT-064992
ACTELION PHARMACEUTICALS LTD
2020 Phase 3 EUCTR2019-004131-24-IT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
Long term oxygen therapy
University of Zurich
2013 Phase 3 NCT01884012 Switzerland;
MACITENTAN COMPRESSE
ACTELION PHARMACEUTICALS LTD
2020 Phase 3 EUCTR2019-004131-24-IT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
Macitentan
Actelion
2020 Phase 3 NCT04271475 Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 NCT03809650 Japan;
2018 Phase 3 NCT03422328 Belarus;Belgium;France;Poland;Russian Federation;Ukraine;
2015 Phase 2 NCT02060721 Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Italy;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 NCT02021292 Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Italy;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam;
Assistance Publique - Hôpitaux de Paris
2021 Phase 2/Phase 3 NCT04780932 France;
Nakano Masayoshi
2021 Phase 3 JPRN-jRCT2051200150 Germany;Hungary;Japan;South Korea;USA;
Macitentan tablets
ACTELION Pharmaceuticals Ltd.
2020 Phase 3 EUCTR2019-004131-24-PL Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-LT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-HU Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-GB Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-ES Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-DE Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
Methyl 4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo [3,4-b]pyridine-3-yl]-5-pyrimidinyl(methyl)carb
Bayer AG
2010 Phase 3 EUCTR2008-003539-19-SK Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2010 - EUCTR2007-000072-16-DK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-SK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-BE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-AT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-PT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-IE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-CZ Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2008-003539-19-DE Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2008 Phase 3 EUCTR2007-000072-16-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2007-000072-16-ES Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
- - EUCTR2007-000072-16-DE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
2009 Phase 3 EUCTR2008-003539-19-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2008-003539-19-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2008-003539-19-IE Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom;
Bayer HealthCare AG, D-51368 Leverkusen
2009 Phase 3 EUCTR2007-000072-16-GB Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Methyl [4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]meth
Bayer HealthCare AG
2006 Phase 1;Phase 2 EUCTR2006-003520-10-DE Germany;
MultiHance
Brigham and Women's Hospital
2013 Phase 2 NCT01953965 United States;
N-acetyl cysteine
Instituto Nacional de Cardiologia Ignacio Chavez
2019 - NCT04081012 Mexico;
NS-304
NIPPON SHINYAKU CO., LTD.
2013 Phase 2 JPRN-JapicCTI-132159 -
NIPPON SHINYAKU CO., LTD. / Actelion Pharmaceuticals Japan Ltd.
2010 Phase 2 JPRN-JapicCTI-111667 -
2010 Phase 2 JPRN-JapicCTI-111666 -
NS-304 Placebo
Nippon Shinyaku Co., Ltd.
2016 Phase 3 JPRN-JapicCTI-163279 Japan;
Opsumit
Actelion Pharmaceuticals Ltd
2021 Phase 3 EUCTR2017-003934-10-PL Belarus;Belgium;France;Germany;Poland;Russian Federation;Turkey;Ukraine;
Actelion Pharmaceuticals Ltd.
2015 Phase 2 EUCTR2013-003457-25-LT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2015 Phase 2 EUCTR2013-002950-56-LT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2015 - EUCTR2013-003457-25-NL Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-HU Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-GB Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-DE Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-BE Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-AT Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-DE Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-CZ Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-BE Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-AT Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
Opsumit®
ACTELION PHARMACEUTICALS LTD
2020 Phase 3 EUCTR2019-004131-24-IT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
ACTELION Pharmaceuticals Ltd.
2020 Phase 3 EUCTR2019-004131-24-PL Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-LT Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-HU Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-GB Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-ES Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
2020 Phase 3 EUCTR2019-004131-24-DE Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
Actelion Pharmaceuticals Ltd.
2014 Phase 2 EUCTR2013-003457-25-FR Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-003457-25-CZ Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;
2014 Phase 2 EUCTR2013-002950-56-NL Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-HU Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam;
2014 Phase 2 EUCTR2013-002950-56-GB Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States;
Oxygen
Department of Cardiology, Hospital Organization Okayama Medical Center
2015 - JPRN-UMIN000026882 Japan;
Heidelberg University
2019 Phase 2 NCT04207593 Germany;
University of Zurich
2015 - NCT02558582 Switzerland;
Oxygen, liquid
Thoraxklinik-Heidelberg gGmbH
2019 Phase 2 EUCTR2018-001387-39-DE Germany;
Placebo
NIPPON SHINYAKU CO., LTD. / Actelion Pharmaceuticals Japan Ltd.
2010 Phase 2 JPRN-JapicCTI-111667 -
Pulmonary Endarteriectomy
Medical University of Vienna
2017 - NCT03074539 Austria;
Pulmonary endarterectomy
International CTEPH Association
2018 Phase 2 NCT03273257 France;Germany;United Kingdom;United States;
Remodulin (R)
MRN-Medical Research Network GmbH
2009 Phase 3 EUCTR2008-006441-10-SK Austria;Czech Republic;Germany;Slovakia;
Remodulin 10mg/ml 20ml
MRN-Medical Research Network GmbH
2010 - EUCTR2008-006441-10-DE Austria;Czech Republic;Germany;
Remodulin 1mg/ml 20ml
MRN-Medical Research Network GmbH
2010 - EUCTR2008-006441-10-DE Austria;Czech Republic;Germany;
Remodulin 2.5mg/ml 20ml
MRN-Medical Research Network GmbH
2010 - EUCTR2008-006441-10-DE Austria;Czech Republic;Germany;
Remodulin 5mg/ml 20ml
MRN-Medical Research Network GmbH
2010 - EUCTR2008-006441-10-DE Austria;Czech Republic;Germany;
Riociguat
Adachi Shiro
2021 - JPRN-jRCT1041210122 Japan;
Assistance Publique - Hôpitaux de Paris
2016 - NCT02634203 France;
Bayer AG
2009 Phase 3 EUCTR2008-003539-19-PT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer AG
2010 Phase 3 EUCTR2008-003539-19-SK Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Bayer HealthCare AG
2010 - EUCTR2007-000072-16-DK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2008-003539-19-AT Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 EUCTR2007-000072-16-SK Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-BE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2007-000072-16-AT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-PT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-IE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2007-000072-16-CZ Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2008-003539-19-DE Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2008 Phase 3 EUCTR2007-000072-16-IT Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2007-000072-16-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2008 Phase 3 EUCTR2007-000072-16-ES Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2006 Phase 1;Phase 2 EUCTR2006-003520-10-DE Germany;
- - EUCTR2007-000072-16-DE Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
2009 Phase 3 EUCTR2008-003539-19-NL Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 Phase 3 EUCTR2008-003539-19-FR Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom;
2009 - EUCTR2008-003539-19-IE Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom;
Bayer HealthCare AG, D-51368 Leverkusen
2009 Phase 3 EUCTR2007-000072-16-GB Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Fukuda Keiichi
2016 - JPRN-jRCTs031180239 Japan;
Heidelberg University
2021 Phase 4 NCT04954742 Germany;
International CTEPH Association
2018 Phase 2 NCT03273257 France;Germany;United Kingdom;United States;
Keio University School of Medicine
2016 - JPRN-UMIN000019549 Japan;
Medical University of Vienna
2017 - NCT03074539 Austria;
Shanghai Pulmonary Hospital
2021 Phase 0 ChiCTR2000032403 China;
Shimokawahara Hiroto
2021 Phase 2 JPRN-jRCTs041200052 Japan;
Riociguat (ADEMPAS, BAY63-2521)
Bayer
2014 - NCT02117791 Japan;
Riociguat (Adempas, BAY63-2521)
Bayer
2015 - NCT02545465 Belgium;Canada;Colombia;Denmark;Germany;Japan;Sweden;Turkey;United Kingdom;
2009 Phase 3 NCT00910429 Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
2009 Phase 3 NCT00855465 Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States;
Riociguat Oral Tablet
National Hospital Organization Okayama Medical Center
2020 Phase 2 NCT04600492 Japan;
Ro 47-0203
Actelion Pharmaceuticals Ltd.
2006 Phase 3 EUCTR2005-002900-40-GB Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-DE Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-CZ Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-BE Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-GB Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-CZ Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-002900-40-AT Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-DE Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-AT Austria;Germany;Italy;Spain;United Kingdom;
Sauerstoff
Thoraxklinik-Heidelberg gGmbH
2019 Phase 2 EUCTR2018-001387-39-DE Germany;
Selexipag
Actelion
2019 Phase 3 NCT03689244 Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czechia;Denmark;Germany;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
Adachi Shiro
2021 - JPRN-jRCT1041210122 Japan;
NIPPON SHINYAKU CO., LTD.
2013 Phase 2 JPRN-JapicCTI-132159 -
NIPPON SHINYAKU CO., LTD. / Actelion Pharmaceuticals Japan Ltd.
2010 Phase 2 JPRN-JapicCTI-111667 -
2010 Phase 2 JPRN-JapicCTI-111666 -
Nippon Shinyaku Co., Ltd.
2016 Phase 3 JPRN-JapicCTI-163279 Japan;
Supplemental oxygen via a mask
University of Zurich
2012 Phase 2 NCT01748474 Switzerland;
Systemic anticoagulation
University of Arizona
2021 - NCT05133713 United States;
TRACLEER 125MG 56CPR RIV.
ACTELION PHARMACEUTICALS ITALIA
2005 - EUCTR2005-001965-33-IT Germany;Italy;Spain;United Kingdom;
TRACLEER*56CPR RIV
ACTELION PHARMACEUTICALS ITALIA
2006 - EUCTR2005-002900-40-IT Czech Republic;Germany;Italy;Spain;United Kingdom;
TREPROSTINIL SODIUM
MRN-Medical Research Network GmbH
2010 - EUCTR2008-006441-10-DE Austria;Czech Republic;Germany;
Thrombin
National and Kapodistrian University of Athens
2015 - NCT03195543 Greece;
Tracleer
Actelion Pharmaceuticals Ltd.
2006 Phase 3 EUCTR2005-002900-40-GB Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom;
2006 - EUCTR2005-002900-40-CZ Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-GB Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 Phase 3 EUCTR2005-001965-33-CZ Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-002900-40-AT Austria;Czech Republic;Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-DE Germany;Italy;Spain;United Kingdom;
2005 - EUCTR2005-001965-33-AT Austria;Germany;Italy;Spain;United Kingdom;
Treprostinil sodium
SciPharm SàRL
2009 Phase 3 NCT01416636 Austria;Czech Republic;Czechia;Germany;Poland;
Uptravi
ACTELION PHARMACEUTICALS LTD
2019 Phase 3 EUCTR2018-002823-41-IT Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Democratic People's Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
Actelion Pharmaceuticals Ltd
2019 Phase 3 EUCTR2018-002823-41-PT Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-NL Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-HU Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-GB Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-DK Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-DE Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-CZ Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-BG Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-BE Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-002823-41-AT Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;
Volibris
GlaxoSmithKline Research & Developement Ltd
2014 Phase 3 EUCTR2012-001646-18-IT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001646-18-NL Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-GB Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-DE Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-CZ Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;
2013 - EUCTR2012-001646-18-AT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
GlaxoSmithKline Research & Developement Ltd
2014 Phase 3 EUCTR2012-001642-17-IT Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;United States;
2013 Phase 3 EUCTR2012-001642-17-GB Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 Phase 3 EUCTR2012-001642-17-CZ Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001642-17-NL Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
2013 - EUCTR2012-001642-17-DE Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Italy;Japan;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;Turkey;United Kingdom;United States;
2013 - EUCTR2012-001642-17-AT Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom;
GlaxoSmithKline, S.A.
2013 - EUCTR2012-001646-18-ES Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States;
2013 - EUCTR2012-001642-17-ES Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States;
Warfarin
Abe Kohtaro
2021 Phase 3 JPRN-jRCT2071200098 Japan;
Division of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine
2016 Phase 4 JPRN-UMIN000018520 Japan;
Warfarin Potassium
Kyushu University
2021 Phase 3 NCT04730037 Japan;
[18F]Fluoro-2-deoxy-2-D-glucose
Brigham and Women's Hospital
2013 Phase 2 NCT01953965 United States;