3. Spinal muscular atrophy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 237 / Drugs : 123 - (DrugBank : 29) / Drug target genes : 51 - Drug target pathways : 75
Spinal muscular atrophy and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability
| ID | Diseases (Sorted by drug repositionability) |
|---|---|
| 3 | Spinal muscular atrophy |
| 13 | Multiple sclerosis/Neuromyelitis optica |
| 6 | Parkinson disease |
| 2 | Amyotrophic lateral sclerosis |
| 5 | Progressive supranuclear palsy |
| 206 | Fragile X syndrome |
| 18 | Spinocerebellar degeneration |
| 17 | Multiple system atrophy |
| 97 | Ulcerative colitis |
| 156 | Rett syndrome |
| 8 | Huntington disease |
| 205 | Fragile X syndrome related disease |
| 193 | Prader-Willi syndrome |
| 140 | Dorabe syndrome |
| 144 | Lennox-Gastaut syndrome |
| 46 | Malignant rheumatoid arthritis |
| 70 | Spinal stenosis |
| 21 | Mitochondrial disease |
| 152 | PCDH19 related syndrome |
| 96 | Crohn disease |
| 34 | Neurofibromatosis |
| 22 | Moyamoya disease |
| 158 | Tuberous sclerosis |
| 145 | West syndrome |
| 203 | 22q11.2 deletion syndrome |
| 231 | Alpha-1-antitrypsin deficiency |
| 201 | Angelman syndrome |
| 296 | Biliary atresia |
| 272 | Fibrodysplasia ossificans progressiva |
| 298 | Hereditary pancreatitis |
| 155 | Acquired aphasia with convulsive disorder |
| 98 | Eosinophilic gastrointestinal disease |
| 75 | Cushing disease |
| 36 | Epidermolysis bullosa |
| 127 | Frontotemporal lobar degeneration |
| 84 | Sarcoidosis |
| 102 | Rubinstein-Taybi syndrome |
| 85 | Idiopathic interstitial pneumonia |
| 256 | Muscle glycogenosis |
| 215 | Tetralogy of Fallot |
| 4 | Primary lateral sclerosis |
| 12 | Congenital myasthenic syndrome |
| 233 | Wolfram syndrome |
| 65 | Primary immunodeficiency |
| 113 | Muscular dystrophy |
| 78 | Hypopituitarism |
| 89 | Lymphangioleiomyomatosis |
| 222 | Primary nephrotic syndrome |
| 49 | Systemic lupus erythematosus |
| 11 | Myasthenia gravis |
| 331 | Idiopathic multicentric castleman disease |
| 26 | HTLV-1-associated myelopathy |
| 14 | Chronic inflammatory demyelinating polyneuropathy |
| 90 | Retinitis pigmentosa |
| 251 | Urea cycle disorder |
| 86 | Pulmonary arterial hypertension |
| 337 | Homocystinuria |
| 76 | Pituitary gonadotropin secretion hyperthyroidism |
| 1 | Spinal and bulbar muscular atrophy |
| 299 | Cystic fibrosis |
| 111 | Congenital myopathy |
| 191 | Werner syndrome |
| 220 | Rapidly progressive glomerulonephritis |
| 30 | Distal myopathy |