DR info

Clinical trials : 133 / Drugs : 186 - (DrugBank : 67) / Drug target genes : 79 - Drug target pathways : 190

Neurofibromatosis and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability

ID	Diseases (Sorted by drug repositionability)
34	Neurofibromatosis
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
2	Amyotrophic lateral sclerosis
6	Parkinson disease
331	Idiopathic multicentric castleman disease
28	Systemic amyloidosis
51	Scleroderma
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
96	Crohn disease
5	Progressive supranuclear palsy
8	Huntington disease
231	Alpha-1-antitrypsin deficiency
22	Moyamoya disease
298	Hereditary pancreatitis
97	Ulcerative colitis
152	PCDH19 related syndrome
65	Primary immunodeficiency
158	Tuberous sclerosis
3	Spinal muscular atrophy
36	Epidermolysis bullosa
26	HTLV-1-associated myelopathy
70	Spinal stenosis
89	Lymphangioleiomyomatosis
21	Mitochondrial disease
206	Fragile X syndrome
193	Prader-Willi syndrome
18	Spinocerebellar degeneration
201	Angelman syndrome
272	Fibrodysplasia ossificans progressiva
140	Dorabe syndrome
256	Muscle glycogenosis
145	West syndrome
144	Lennox-Gastaut syndrome
205	Fragile X syndrome related disease
156	Rett syndrome
98	Eosinophilic gastrointestinal disease
86	Pulmonary arterial hypertension
17	Multiple system atrophy
155	Acquired aphasia with convulsive disorder
56	Behcet disease
296	Biliary atresia
266	Familial mediterranean fever
75	Cushing disease
58	Hypertrophic cardiomyopathy
49	Systemic lupus erythematosus
42	Polyarteritis nodosa
113	Muscular dystrophy
222	Primary nephrotic syndrome
102	Rubinstein-Taybi syndrome
107	Juvenile idiopathic arthritis
228	Bronchiolitis obliterans
280	Huge arteriovenous malformation with cervicofacial or limb lesion
127	Frontotemporal lobar degeneration
164	Oculocutaneous albinism
93	Primary biliary cholangitis
35	Pemphigus
210	Single Ventricle
233	Wolfram syndrome
87	Pulmonary veno-occlusive disease
226	Interstitial cystitis with Hunners ulcer
38	Stevens-Johnson syndrome
90	Retinitis pigmentosa
227	Osler disease
11	Myasthenia gravis
279	Huge venous malformation with cervical, oral and pharyngeal diffuse lesion
171	Wilson disease
323	Aromatic L-amino acid decarboxylase deficiency
168	Ehlers-Danlos syndrome
1	Spinal and bulbar muscular atrophy
162	Pemphigoid
50	Dermatomyositis
10	Charcot-Marie-Tooth disease
215	Tetralogy of Fallot
333	Hutchinson-Gilford syndrome
53	Sjogren syndrome
60	Aplastic anemia
337	Homocystinuria
41	Giant cell arteritis
67	Polycystic kidney disease
149	Hemiconvulsion hemiplegia epilepsy syndrome
271	Ankylosing spondylitis
114	Non-dystrophic myotonia syndrome
270	Chronic recurrent multifocal osteomyelitis
88	Chronic thromboembolic pulmonary hypertension
172	Hypophosphatasia
25	Progressive multifocal leukoencephalopathy
118	Myelomeningocele
212	Tricuspid atresia
78	Hypopituitarism
285	Fanconi anemia
169	Menkes disease
170	Occipital horn syndrome
283	Acquired pure red cell aplasia
45	Eosinophilic granulomatosis with Polyangiitis
288	Autoimmune acquired coagulation factor deficiency
106	Cryopyrin-associated periodic syndrome
251	Urea cycle disorder
137	Focal cortical dysplasia
192	Cockayne syndrome
277	Lymphangiomatosis
281	Klippel-Trenaunay-Weber syndrome
108	TNF receptor-associated periodic syndrome
267	Hyper-IgD syndrome