1 |
Abemaciclib
| [1] Abemaciclib Abemaciclib | [1] Abemaciclib
Abemaciclib
💬 | [2] CDK4 CDK4, CDK6 💬 | [29] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Breast cancer, Cell cycle, Cellular senescence, Chronic myeloid leukemia, Cushing syndrome, Endocrine resistance, Epstein-Barr virus infection, Glioma, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Measles, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Small cell lung cancer, T cell receptor signaling pathway, Tight junction, Viral carcinogenesis, p53 signaling pathway 💬 | [1] 34 34 💬 |
2 |
Acetaminophen
| [4] Acetaminophen Acetaminophen; Paracetamol; Tylenol; Ultracet | [1] Acetaminophen
Acetaminophen
💬 | [2] PTGS1 PTGS1, PTGS2 💬 | [23] Alzheimer disease Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬 | [15] 3 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 |
3 |
Aminolevulinic acid
| [4] 5-ALA 5-ALA; 5-aminolevulinic acid; Aminolevulinic acid; Gliolan | [1] Aminolevulinic acid
Aminolevulinic acid
💬 | - | - | [5] 34 34, 96, 97, 180, 286 💬 |
4 |
AR-42
| [1] AR-42 AR-42 | - | - | - | [1] 34 34 💬 |
5 |
Axitinib
| [1] Axitinib Axitinib | [1] Axitinib
Axitinib
💬 | [3] FLT1 FLT1, FLT4, KDR 💬 | [15] Breast cancer Breast cancer, Calcium signaling pathway, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Rheumatoid arthritis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬 | [1] 34 34 💬 |
6 |
Bevacizumab
| [2] AVASTIN AVASTIN; Bevacizumab | [1] Bevacizumab
Bevacizumab
💬 | [1] VEGFA VEGFA 💬 | [24] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬 | [6] 13 13, 34, 85, 87, 227, 280 💬 |
7 |
Bevacizumab zirconium Zr-89
| [2] 89ZR-BEVACIZUMAB 89ZR-BEVACIZUMAB; BEVACIZUMAB ZIRCONIUM ZR-89 | - | - | - | [1] 34 34 💬 |
8 |
Binimetinib
| [1] Binimetinib Binimetinib | [1] Binimetinib
Binimetinib
💬 | [2] MAP2K1 MAP2K1, MAP2K2 💬 | [89] Acute myeloid leukemia Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬 | [1] 34 34 💬 |
9 |
Brigatinib
| [1] Brigatinib Brigatinib | [1] Brigatinib
Brigatinib
💬 | [1] ALK ALK 💬 | [3] Non-small cell lung cancer Non-small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer 💬 | [1] 34 34 💬 |
10 |
Butyric Acid
| [4] Butanoic acid Butanoic acid; Butyrate; Butyric Acid; Sodium Butyrate | - | - | - | [7] 34 34, 46, 51, 97, 156, 222, 291 💬 |
11 |
Cabozantinib
| [1] Cabozantinib Cabozantinib | [1] Cabozantinib
Cabozantinib
💬 | [3] AXL AXL, KDR, MET 💬 | [25] Adherens junction Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, EGFR tyrosine kinase inhibitor resistance, Epithelial cell signaling in Helicobacter pylori infection, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, Hepatocellular carcinoma, MAPK signaling pathway, Malaria, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Renal cell carcinoma, Transcriptional misregulation in cancer, VEGF signaling pathway 💬 | [1] 34 34 💬 |
12 |
Carboplatin
| [2] Carboplatin Carboplatin; CBDCA | [1] Carboplatin
Carboplatin
💬 | - | - | [4] 28 28, 34, 60, 85 💬 |
13 |
Cediranib
| [1] Cediranib Cediranib | [1] Cediranib
Cediranib
💬 | [3] FLT1 FLT1, FLT4, KDR 💬 | [15] Breast cancer Breast cancer, Calcium signaling pathway, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Rheumatoid arthritis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬 | [1] 34 34 💬 |
14 |
Celecoxib
| [2] CELEBREX CELEBREX; Celecoxib | [1] Celecoxib
Celecoxib
💬 | [1] PTGS2 PTGS2 💬 | [22] Alzheimer disease Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬 | [10] 2 2, 3, 34, 46, 70, 89, 107, 161, 171, 271 💬 |
15 |
Chloride ion
| [1] Chloride Chloride | - | - | - | [28] 6 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338 💬 |
16 |
Cholecalciferol
| [5] Cholecalciferol Cholecalciferol; Colecalciferol; Multivitamin; Vitamin D; Vitamin D3 | [1] Cholecalciferol
Cholecalciferol
💬 | [1] VDR VDR 💬 | [5] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬 | [24] 6 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
17 |
Crizotinib
| [1] Crizotinib Crizotinib | [1] Crizotinib
Crizotinib
💬 | [1] ALK ALK 💬 | [3] Non-small cell lung cancer Non-small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer 💬 | [1] 34 34 💬 |
18 |
Cysteine
| [2] Cysteine Cysteine; Cysteine hydrochloride | - | - | - | [10] 13 13, 19, 34, 84, 85, 88, 90, 254, 296, 310 💬 |
19 |
Dabrafenib
| [1] Dabrafenib Dabrafenib | [1] Dabrafenib
Dabrafenib
💬 | [1] BRAF BRAF 💬 | [44] Acute myeloid leukemia Acute myeloid leukemia, Alcoholism, Alzheimer disease, Bladder cancer, Breast cancer, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanoma, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Regulation of actin cytoskeleton, Renal cell carcinoma, Serotonergic synapse, Thyroid cancer, Vascular smooth muscle contraction, cAMP signaling pathway, mTOR signaling pathway 💬 | [1] 34 34 💬 |
20 |
Dexmedetomidine
| [4] Dexdor Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE | [1] Dexmedetomidine
Dexmedetomidine
💬 | [3] ADRA2A ADRA2A, ADRA2B, ADRA2C 💬 | [2] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬 | [14] 2 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 |
21 |
Diclofenac
| [3] Diclofenac Diclofenac; Diclofenac Sodium; Diclofenac SR | [1] Diclofenac
Diclofenac
💬 | [2] PTGS1 PTGS1, PTGS2 💬 | [23] Alzheimer disease Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬 | [5] 13 13, 34, 46, 78, 271 💬 |
22 |
Doxorubicin
| [2] Doxorubicin Doxorubicin; Doxorubicin Hydrochloride | [1] Doxorubicin
Doxorubicin
💬 | [2] TOP2A TOP2A, TOP2B 💬 | [1] Platinum drug resistance Platinum drug resistance 💬 | [5] 26 26, 28, 34, 65, 331 💬 |
23 |
Doxycycline
| [4] Doxycyclin Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets | [2] Doxycycline
Doxycycline
,
Doxycycline
💬 | - | - | [17] 13 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬 |
24 |
Endostatin
| [1] Endostatin Endostatin | - | - | - | [1] 34 34 💬 |
25 |
Etoposide
| [1] Etoposide Etoposide | [1] Etoposide
Etoposide
💬 | [2] TOP2A TOP2A, TOP2B 💬 | [1] Platinum drug resistance Platinum drug resistance 💬 | [11] 11 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬 |
26 |
Everolimus
| [4] Afinitor Afinitor; Certican; Everolimus; Votubia | [1] Everolimus
Everolimus
💬 | [1] MTOR MTOR 💬 | [51] AMPK signaling pathway AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬 | [9] 34 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
27 |
Filgrastim
| [7] Filgrastim Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; ZARZIO | [1] Filgrastim
Filgrastim
💬 | [1] CSF3R CSF3R 💬 | [5] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬 | [35] 2 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
28 |
Gadolinium
| [1] Gadolinium Gadolinium | - | - | - | [4] 13 13, 34, 46, 65 💬 |
29 |
Gold
| [1] Gold Gold | - | - | - | [43] 2 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬 |
30 |
Hydroxychloroquine
| [3] HYDROXYCHLOROQUINE HYDROXYCHLOROQUINE; HYDROXYCHLOROQUINE SULFATE; Plaquenil | [1] Hydroxychloroquine
Hydroxychloroquine
💬 | - | - | [27] 13 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬 |
31 |
Icotinib
| [1] Icotinib Icotinib | [1] Icotinib
Icotinib
💬 | [1] EGFR EGFR 💬 | [48] Adherens junction Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬 | [1] 34 34 💬 |
32 |
Ifosfamide
| [1] Ifosfamide Ifosfamide | [1] Ifosfamide
Ifosfamide
💬 | - | - | [1] 34 34 💬 |
33 |
Imatinib
| [4] Gleevec Gleevec; GLIVEC; IMATINIB; Imatinib Mesylate | [1] Imatinib
Imatinib
💬 | [3] ABL1 ABL1, KIT, PDGFRA 💬 | [32] Acute myeloid leukemia Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬 | [12] 13 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
34 |
Imiquimod
| [1] Imiquimod Imiquimod | [1] Imiquimod
Imiquimod
💬 | [1] TLR7 TLR7 💬 | [5] Coronavirus disease - COVID-19 Coronavirus disease - COVID-19, Influenza A, Measles, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway 💬 | [2] 34 34, 51 💬 |
35 |
Interferon alfa-2b
| [2] Interferon alfa-2b Interferon alfa-2b; Interferon alpha-2B | [1] Interferon alfa-2b
Interferon alfa-2b
💬 | [2] IFNAR1 IFNAR1, IFNAR2 💬 | [18] Coronavirus disease - COVID-19 Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬 | [2] 25 25, 34 💬 |
36 |
Iodide
| [1] Iodide Iodide | - | - | - | [1] 34 34 💬 |
37 |
Lamotrigine
| [2] Lamictal Lamictal; LAMOTRIGINE | [1] Lamotrigine
Lamotrigine
💬 | [5] SCN1A SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 | [3] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬 | [5] 13 13, 34, 38, 114, 144 💬 |
38 |
Lapatinib
| [1] Lapatinib Lapatinib | [1] Lapatinib
Lapatinib
💬 | [2] EGFR EGFR, ERBB2 💬 | [50] Adherens junction Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction 💬 | [3] 34 34, 74, 75 💬 |
39 |
Lenalidomide
| [2] Lenalidomide Lenalidomide; REVLIMID | [1] Lenalidomide
Lenalidomide
💬 | [1] TNF TNF 💬 | [67] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [8] 16 16, 26, 28, 34, 49, 284, 300, 331 💬 |
40 |
Lidocaine
| [4] Aloe Aloe; Lidocaine; Lignocaine; Xylocaine | [2] Lidocaine
Lidocaine
,
Lidocaine hydrochloride monohydrate
💬 | [5] SCN1A SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 | [3] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬 | [13] 6 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 |
41 |
Lovastatin
| [1] Lovastatin Lovastatin | [1] Lovastatin
Lovastatin
💬 | [1] HMGCR HMGCR 💬 | [4] AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | [11] 6 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
42 |
Methionine
| [3] Butanoic acid Butanoic acid; L-methionine; Methionine | [1] Methionine
Methionine
💬 | - | - | [6] 34 34, 84, 93, 229, 298, 300 💬 |
43 |
Methotrexate
| [6] Methotrexat Methotrexat; Methotrexate; METHOTREXATE SODIUM; Metoject; METOTREXATO; Méthotrexate | [1] Methotrexate
Methotrexate
💬 | [2] DHFR DHFR, DHFR2 💬 | [5] Antifolate resistance Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬 | [38] 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
44 |
Methylphenidate
| [3] Methylphenidate Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin | [1] Methylphenidate
Methylphenidate
💬 | [2] SLC6A2 SLC6A2, SLC6A3 💬 | [7] Alcoholism Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬 | [7] 6 6, 13, 34, 84, 113, 179, 206 💬 |
45 |
Mirdametinib
| [2] Mirdametinib Mirdametinib; PD-0325901 | [1] Mirdametinib
Mirdametinib
💬 | [2] MAP2K1 MAP2K1, MAP2K2 💬 | [89] Acute myeloid leukemia Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬 | [1] 34 34 💬 |
46 |
Neratinib
| [1] Neratinib Neratinib | [1] Neratinib
Neratinib
💬 | [3] EGFR EGFR, ERBB2, ERBB4 💬 | [51] Adherens junction Adherens junction, Amyotrophic lateral sclerosis, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction 💬 | [1] 34 34 💬 |
47 |
Nilotinib
| [2] Nilotinib Nilotinib; TASIGNA | [1] Nilotinib
Nilotinib
💬 | [4] ABL1 ABL1, KIT, PDGFRA, PDGFRB 💬 | [33] Acute myeloid leukemia Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬 | [5] 6 6, 8, 34, 51, 86 💬 |
48 |
Nitrous oxide
| [2] MEOPA MEOPA; Nitrous Oxide | [1] Nitrous oxide
Nitrous oxide
💬 | - | - | [2] 34 34, 149 💬 |
49 |
Pexidartinib
| [1] Turalio Turalio | [1] Pexidartinib
Pexidartinib
💬 | [3] CSF1R CSF1R, FLT3, KIT 💬 | [15] Acute myeloid leukemia Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬 | [1] 34 34 💬 |
50 |
Pirfenidone
| [2] Esbriet Esbriet; Pirfenidone | [1] Pirfenidone
Pirfenidone
💬 | [6] CCL2 CCL2, IL10, IL1A, IL1B, IL6, TNF 💬 | [84] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [11] 13 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
51 |
Propofol
| [2] Propofol Propofol; Propofol Injection | [1] Propofol
Propofol
💬 | [16] GABRA1 GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 | [7] GABAergic synapse GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬 | [9] 6 6, 21, 22, 34, 46, 70, 75, 98, 296 💬 |
52 |
PTC299
| [1] PTC299 PTC299 | - | - | - | [1] 34 34 💬 |
53 |
Ranibizumab
| [3] Lucentis Lucentis; RANIBIZUMAB; RhuFab V2 | [1] Ranibizumab
Ranibizumab
💬 | [1] VEGFA VEGFA 💬 | [24] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬 | [4] 34 34, 166, 227, 301 💬 |
54 |
Selumetinib
| [2] Koselugo Koselugo; Selumetinib | [1] Selumetinib
Selumetinib
💬 | [2] MAP2K1 MAP2K1, MAP2K2 💬 | [89] Acute myeloid leukemia Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬 | [1] 34 34 💬 |
55 |
Sevoflurane
| [1] Sevoflurane Sevoflurane | [1] Sevoflurane
Sevoflurane
💬 | - | - | [7] 6 6, 21, 22, 34, 98, 225, 296 💬 |
56 |
Simvastatin
| [3] Simvastatin Simvastatin; Simvastatina; Simvastatine | [1] Simvastatin
Simvastatin
💬 | [1] HMGCR HMGCR 💬 | [4] AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | [21] 6 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
57 |
Sirolimus
| [3] RAPAMUNE RAPAMUNE; Rapamycin; SIROLIMUS | [1] Sirolimus
Sirolimus
💬 | [1] MTOR MTOR 💬 | [51] AMPK signaling pathway AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬 | [40] 2 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
58 |
Sodium chloride
| [6] Lactated Ringers Lactated Ringers; Natriumchlorid; REBIF; Saline; Sodium chloride; Sporanox | [1] Sodium chloride
Sodium chloride
💬 | - | - | [20] 6 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299 💬 |
59 |
Sodium iodide
| [1] Sodium iodide Sodium iodide | [3] Sodium iodide
Sodium iodide
,
Sodium iodide I 123
,
Sodium iodide I 125
💬 | - | - | [1] 34 34 💬 |
60 |
Sorafenib
| [2] Nexavar Nexavar; Sorafenib | [1] Sorafenib
Sorafenib
💬 | [8] BRAF BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1, RET 💬 | [89] Acute myeloid leukemia Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬 | [2] 34 34, 86 💬 |
61 |
Sulfate ion
| [1] Sulfate Sulfate | - | - | - | [27] 2 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299 💬 |
62 |
Sunitinib
| [2] Sunitinib Sunitinib; Sunitinib malate | [1] Sunitinib
Sunitinib
💬 | [9] CSF1R CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB, RET 💬 | [36] Acute myeloid leukemia Acute myeloid leukemia, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Thyroid cancer, Transcriptional misregulation in cancer, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬 | [2] 28 28, 34 💬 |
63 |
Temozolomide
| [1] Temozolomide Temozolomide | [1] Temozolomide
Temozolomide
💬 | - | - | [1] 34 34 💬 |
64 |
Tipifarnib
| [1] Tipifarnib Tipifarnib | [1] Tipifarnib
Tipifarnib
💬 | [2] FNTA FNTA, FNTB 💬 | [1] Terpenoid backbone biosynthesis Terpenoid backbone biosynthesis 💬 | [1] 34 34 💬 |
65 |
Trametinib
| [2] Mekinist Mekinist; Trametinib | [1] Trametinib
Trametinib
💬 | [2] MAP2K1 MAP2K1, MAP2K2 💬 | [89] Acute myeloid leukemia Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬 | [4] 2 2, 34, 279, 280 💬 |
66 |
Vinblastine
| [2] Vinblastine Vinblastine; Vinblastine sulfate | [1] Vinblastine
Vinblastine
💬 | [9] TUBB TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 | [10] Alzheimer disease Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬 | [2] 34 34, 65 💬 |
67 |
Vincristine
| [2] Vincristine Vincristine; Vincristine Sulfate | [1] Vincristine
Vincristine
💬 | [9] TUBB TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 | [10] Alzheimer disease Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬 | [4] 26 26, 34, 65, 331 💬 |