299. 嚢胞性線維症 [臨床試験数:1,592,薬物数:1,539(DrugBank:255),標的遺伝子数:81,標的パスウェイ数:162

Searched query = "Cystic fibrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
6 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04039087September 5, 201928/7/2019Sildenafil Exercise: Role of PDE5 InhibitionMechanisms of Exercise Intolerance in Cystic Fibrosis: Role of PDE5 InhibitionCystic FibrosisDrug: Sildenafil 40mg oral capsule;Drug: Placebo Oral capsuleNational Jewish HealthAugusta University;Cystic Fibrosis FoundationRecruiting9 YearsN/AAll40Phase 2/Phase 3United States
2NCT02626182December 20153/12/2015Evaluation and Treatment of Pulmonary Vascular Disease in Moderate to Severe CFEvaluation and Treatment of Pulmonary Vascular Disease in Moderate to Severe Cystic Fibrosis Lung DiseaseCystic FibrosisDrug: sildenafil;Drug: placeboNational Jewish HealthNULLCompleted18 YearsN/AAll14Phase 1/Phase 2United States
3NCT01132482October 201516/4/2010Effects of Sildenafil on CFTR-dependent Ion Transport ActivityPhase II Study of the Effects of Sildenafil on CFTR-dependent Ion Transport ActivityCystic FibrosisDrug: Sildenafil;Drug: PlaceboNational Jewish HealthNULLCompleted18 YearsN/AAll19Phase 2United States
4NCT02057458April 20144/2/2014Blood Flow and Vascular Function in Cystic FibrosisRole of Blood Flow and Vascular Function on Exercise Capacity in Cystic FibrosisCystic FibrosisDrug: Sildenafil (Acute-1 hour);Drug: Sildenafil (Subchronic-4 weeks);Drug: PlaceboAugusta UniversityNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Completed18 YearsN/AAll19Phase 2United States
5NCT01194232August 20121/9/2010Sildenafil Trial in Children and Young Adults With CFRandomized Controlled Study of Sildenafil in Children and Young Adults With Mild to Moderate Cystic Fibrosis Lung DiseaseCystic Fibrosis With Mild to Moderate Lung Disease;CMRI of Lung Perfusion;Lung Perfusion;Lung VascularizationDrug: SildenafilChildren's Hospital Medical Center, CincinnatiNULLWithdrawn8 Years21 YearsBoth0Phase 1/Phase 2United States
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6NCT00659529August 200814/4/2008Safety and Efficacy of Sildenafil in Cystic Fibrosis (CF) Lung DiseaseThe Role of Phosphodiesterase Inhibitors in CF Lung DiseaseCystic FibrosisDrug: sildenafilNational Jewish HealthCystic Fibrosis FoundationCompleted14 YearsN/AAll36Phase 1/Phase 2United States