Xenon    (DrugBank: Xenon)

4 diseases
告示番号疾患名(ページ内リンク)臨床試験数
22もやもや病1
85特発性間質性肺炎3
228閉塞性細気管支炎2
299嚢胞性線維症7

22. もやもや病 [臨床試験数:11,薬物数:18(DrugBank:11),標的遺伝子数:28,標的パスウェイ数:43
Searched query = "Moyamoya disease", "Occlusive disease in circle of Willis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 11 trial found
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1NCT01419275
(ClinicalTrials.gov)
April 200916/8/2011Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke PatientsQuantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke PatientsCerebrovascular Accident;Moyamoya DiseaseDrug: Xenon contrast agent;Device: Magnetic Resonance ImagingStanford UniversityNULLCompletedN/AN/AAll126N/AUnited States

85. 特発性間質性肺炎 [臨床試験数:514,薬物数:377(DrugBank:108),標的遺伝子数:97,標的パスウェイ数:204
Searched query = "Idiopathic interstitial pneumonia", "IIPs", "Idiopathic pulmonary fibrosis", "IPF", "Usual interstitial pneumonia", "UIP", "Non-specific interstitial pneumonia", "NSIP", "Acute interstitial pneumonia", "AIP", "Diffuse alveolar damage", "DAD", "COP", "Organizing pneumonia", "OP", "Desquamative interstitial pneumonia", "DIP", "Respiratory bronchiolitis - associated interstitial lung disease", "RB-ILD", "Lymphocytic interstitial pneumonia", "LIP"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 514 trials found
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1NCT04071769
(ClinicalTrials.gov)
August 3, 20209/8/2019Genentech Xenon MRI Idiopathic Pulmonary FibrosisUsing Xenon MRI to Evaluate the Efficacy of Therapies for Idiopathic Pulmonary FibrosisIdiopathic Pulmonary FibrosisDrug: Hyperpolarized 129 Xenon Gas Comparing Idiopathic Pulmonary Fibrosis (IPF) TreatmentDuke UniversityNULLRecruiting18 YearsN/AAll20Phase 2United States
2NCT02478268
(ClinicalTrials.gov)
May 201516/6/2015Using MRI to Visualize Regional Therapy Response in Idiopathic Pulmonary FibrosisUsing MRI to Visualize Regional Therapy Response in Idiopathic Pulmonary FibrosisIdiopathic Pulmonary FibrosisDrug: Hyperpolarized 129-Xenon gas;Device: MRIBastiaan DriehuysUniversity of Wisconsin, Madison;National Heart, Lung, and Blood Institute (NHLBI)Completed18 YearsN/AAll64Phase 1United States
3NCT01280994
(ClinicalTrials.gov)
January 20119/1/2011Hyperpolarized 129Xe MRI for Imaging Pulmonary FunctionHyperpolarized 129Xe MR Imaging of the Lung Function in Healthy Volunteers and Subjects With Pulmonary DiseaseInterstitial Lung Disease;Cystic Fibrosis;Pulmonary Hypertension;NSIPDrug: XenonBastiaan DriehuysNULLRecruiting18 Years80 YearsAll445Phase 1United States

228. 閉塞性細気管支炎 [臨床試験数:92,薬物数:125(DrugBank:34),標的遺伝子数:33,標的パスウェイ数:152
Searched query = "Bronchiolitis obliterans", "Obliterating bronchiolitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 92 trials found
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1NCT03603899
(ClinicalTrials.gov)
August 20204/10/2017Hp129 Xenon Imaging and BOS in Lung TransplantationImaging and Understanding Bronchiolitis Obliterans Syndrome (BOS) in Lung Transplantation With Hyperpolarized 129Xenon MR Lung ImagingBronchiolitis ObliteransDrug: Hp 129XenonChildren's Hospital Medical Center, CincinnatiNULLRecruiting6 YearsN/AAll45Phase 1/Phase 2United States
2NCT04029636
(ClinicalTrials.gov)
August 20197/6/2019Hyperpolarized 129Xe MRI for the Assessment of BOS With Late Onset LONIPCHyperpolarized 129Xe Magnetic Resonance Imaging for the Early Detection of Bronchiolitis Obliterans Syndrome (BOS) and Other Late Onset Non-infectious Pulmonary Complications (LONIPCs) Following Hematopoietic Stem Cell TransplantationBronchiolitis ObliteransOther: Inhaled Hyperpolarized Xenon-129Hamilton Health Sciences CorporationNULLNot yet recruiting18 Years70 YearsAll45Canada

299. 嚢胞性線維症 [臨床試験数:1,592,薬物数:1,539(DrugBank:255),標的遺伝子数:81,標的パスウェイ数:162
Searched query = "Cystic fibrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
7 / 1,592 trials found
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1NCT04467957
(ClinicalTrials.gov)
October 1, 202019/6/2020Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic FibrosisNon-contrast Lung Perfusion Mapping Applied for New Insights in Cystic FibrosisCystic FibrosisDrug: Initiation of CFTR Modulator;Drug: Hyperpolarized Xenon 129Children's Hospital Medical Center, CincinnatiNULLNot yet recruiting6 Years21 YearsAll26Phase 4NULL
2NCT03593434
(ClinicalTrials.gov)
July 30, 201828/6/2018Airway Clearance Therapy on Hyperpolarized 129Xenon and MRIThe Effect of Airway Clearance Therapy on Hyperpolarized 129Xenon MRI Compared With Lung Clearance Index and Spirometry in Cystic FibrosisCystic FibrosisDrug: hyperpolarized Xenon gasChildren's Hospital Medical Center, CincinnatiNational Heart, Lung, and Blood Institute (NHLBI)Recruiting6 Years21 YearsAll20United States
3NCT03482960
(ClinicalTrials.gov)
May 29, 201823/3/2018Comparison of 129Xe MRI With 19F MRI in CF Lung DiseaseComparison of 129Xe MRI With 19F MRI in CF Lung DiseaseCystic FibrosisDrug: Hyperpolarized Xenon gas;Drug: PFPUniversity of North Carolina, Chapel HillCystic Fibrosis FoundationCompleted18 YearsN/AAll15Early Phase 1United States
4NCT02912637
(ClinicalTrials.gov)
October 201613/9/2016Hyperpolarized Xenon Imaging in Patients With Cystic FibrosisHyperpolarised 129Xe MRI for Non-invasive Assessment of Ventilation, Perfusion and the Alveolar Membrane - a Physiological Study in Healthy Volunteers & Cystic Fibrosis PatientsCystic FibrosisOther: Hyperpolarized Xenon MRIPapworth Hospital NHS Foundation TrustUniversity of SheffieldSuspended18 Years70 YearsAll30United Kingdom
5NCT02848560
(ClinicalTrials.gov)
March 201626/7/2016Monitoring Response to Orkambi in Cystic Fibrosis Lung Disease by Inhaled Xenon MRIValidation of MRI as a Sensitive Tool to Longitudinally Monitor CF Lung Disease Progression and Response to CFTR Modulator Therapy in Young Children With CFCystic FibrosisDrug: Hyperpolarized XenonChildren's Hospital Medical Center, CincinnatiNational Heart, Lung, and Blood Institute (NHLBI)Recruiting6 Years12 YearsAll38United States
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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PhaseCountries
6NCT02740868
(ClinicalTrials.gov)
August 201519/8/2015Xenon-129 Lung Magnetic Resonance Imaging: Study of Healthy Volunteers and Participants With Pulmonary DiseaseDevelopment of Hyperpolarized Xenon-129 Lung Magnetic Resonance Imaging: Comparative Pilot Study of Healthy Volunteers and Participants With Pulmonary DiseaseCystic Fibrosis;AsthmaDrug: Xenon-129;Device: Magnetic Resonance Imaging;Device: Lung Clearance IndexThe Hospital for Sick ChildrenNULLRecruiting8 YearsN/AAll30Phase 2Canada
7NCT01280994
(ClinicalTrials.gov)
January 20119/1/2011Hyperpolarized 129Xe MRI for Imaging Pulmonary FunctionHyperpolarized 129Xe MR Imaging of the Lung Function in Healthy Volunteers and Subjects With Pulmonary DiseaseInterstitial Lung Disease;Cystic Fibrosis;Pulmonary Hypertension;NSIPDrug: XenonBastiaan DriehuysNULLRecruiting18 Years80 YearsAll445Phase 1United States