230. Alveolar hypoventilation syndrome
8 clinical trials, 11 drugs (DrugBank: 5 drugs), 18 drug target genes, 27 drug target pathways
Searched query = "Alveolar hypoventilation syndrome", "AHS", "Hypoventilation syndrome", "OHS", "CCHS", "Idiopathic central alveolar hypoventilation", "ICAH"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04108819 (ClinicalTrials.gov) | October 30, 2019 | 26/9/2019 | Ketogenic Diet for Obesity Hypoventilation Syndrome | Ketogenic Diet for Obesity Hypoventilation Syndrome | Obesity Hypoventilation Syndrome;Ketogenic Dieting;Hypercapnic Respiratory Failure | Dietary Supplement: Ketogenic Diet | Johns Hopkins University | NULL | Recruiting | 18 Years | 75 Years | All | 10 | N/A | United States |
| 2 | NCT01964339 (ClinicalTrials.gov) | October 9, 2013 | 14/10/2013 | Obesity Hypoventilation Syndrome Prevalence Study | Obesity Hypoventilation Syndrome Prevalence Study | Obesity Hypoventilation Syndrome | Other: BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (venous blood gas and metabolic panel) and data collection from PSG study.;Other: BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (arterial blood gas and metabolic panel) and data collection from PSG study. | Philips Respironics | NULL | Terminated | 21 Years | N/A | All | 44 | United States | |
| 3 | NCT01500473 (ClinicalTrials.gov) | February 2012 | 22/12/2011 | Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome | Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome | Congenital Central Hypoventilation Syndrome | Drug: Desogestrel | Children's Hospital Los Angeles | NULL | Not yet recruiting | 16 Years | 50 Years | Female | 8 | N/A | United States |
| 4 | NCT01499485 (ClinicalTrials.gov) | November 2011 | 20/12/2011 | Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation. | Effects of Acetazolamide on the Duration of Mechanical Ventilation in Patients With Metabolic Alkalosis. Phase III Multicenter Double-blinded Clinical Trial. | Pulmonary Disease, Chronic Obstructive;Obesity Hypoventilation Syndrome;Metabolic Alkalosis | Drug: Acetazolamide;Drug: Placebo | Hospital Son Llatzer | NULL | Completed | 18 Years | N/A | Both | 140 | Phase 3 | Spain |
| 5 | NCT01243697 (ClinicalTrials.gov) | April 2011 | 17/11/2010 | Assessment of Desogestrel in Ondine Syndrome | Assessment of Desogestrel for a Pharmacological Recovery of Ventilatory Activity in Congenital Central Hypoventilation Syndrome - Ondine Syndrome | Ondine Syndrome | Drug: desogestrel | Assistance Publique - Hôpitaux de Paris | NULL | Completed | 10 Years | 60 Years | Female | 6 | Phase 2;Phase 3 | France |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 6 | ChiCTR-DDT-11001215 | 2010-07-01 | 2011-03-05 | Double position CT investigation of OSAHS | Double position CT investigation of OSAHS | Obstructive sleep apnea hypoventilation syndrome | Gold Standard:;Index test:; | First Hospital of Peking university | NULL | Completed | Both | Target condition:0;Difficult condition:0 | China | |||
| 7 | EUCTR2005-005950-33-SE (EUCTR) | 07/06/2006 | 10/04/2006 | Studie av Domperidon och barn med kongenitalt centralt hypoventilationssyndrom. - DOMPCCHSSWE1 | Studie av Domperidon och barn med kongenitalt centralt hypoventilationssyndrom. - DOMPCCHSSWE1 | Congenital central hypoventilation syndrome, CCHS or Ondine's curse. | Trade Name: Motilium Product Name: Motilium INN or Proposed INN: Domperidone | Karolinska Universitetssjukhuset | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | Sweden | ||||
| 8 | EUCTR2011-000989-35-FR (EUCTR) | 06/05/2011 | N/A | N/A - RESPIRONDINE | MedDRA version: 14.0;Level: PT;Classification code 10066131;Term: Congenital central hypoventilation syndrome;System Organ Class: 10010331 - Congenital, familial and genetic disorders | Trade Name: Cerazette Product Name: Cerazette INN or Proposed INN: Désogestrel | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP) | NULL | NA | Female: yes Male: no | Phase 2 | France |