Procedure: liver biopsy    (DrugBank: -)

3 diseases
IDDisease name (Link within this page)Number of trials
171Wilson disease1
231Alpha-1-antitrypsin deficiency1
240Phenylketonuria1

171. Wilson disease    [ 50 clinical trials,   59 drugs,   (DrugBank: 17 drugs),   3 drug target genes,   28 drug target pathways]
Searched query = "Wilson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 50 trial found
No.TrialIDDate_
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1NCT02702765
(ClinicalTrials.gov)
February 201626/2/2016sCD163 and sMR in Wilsons Disease - Associations With Disease Severity and FibrosisMacrophages and the Macrophage Activation Markers sCD163 and Mannose Receptor (sMR) in Patients With Wilsons Disease - Associations With Liver Disease Severity and FibrosisWilsons DiseaseProcedure: Fibroscan;Procedure: Ultrasound;Drug: Galactose;Procedure: Liver biopsy;Procedure: Functional hepatic nitrogen clearanceUniversity of AarhusAarhus University HospitalActive, not recruiting18 Years100 YearsAll33N/ADenmark

231. Alpha-1-antitrypsin deficiency    [ 83 clinical trials,   89 drugs,   (DrugBank: 16 drugs),   35 drug target genes,   46 drug target pathways]
Searched query = "Alpha-1-antitrypsin deficiency", "AATD"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 83 trial found
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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agemax
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1NCT01810458
(ClinicalTrials.gov)
October 20136/3/2013Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (Liver AATD)Clinical Predictors and Epigenetic Markers for Liver Fibrosis in Alpha-1 Antitrypsin DeficiencyLiver Fibrosis;Alpha-1 Antitrypsin Deficiency;AAT Deficiency;AATDDevice: Abdominal ultrasound;Procedure: History and physical;Procedure: Intravenous catheter;Procedure: Blood draw;Other: Liver questionnaire;Procedure: Liver Biopsy;Drug: Midazolam;Drug: Fentanyl;Drug: Lidocaine;Drug: Acetaminophen;Drug: Lorazepam;Drug: Oxycodone/Acetaminophen;Drug: OndansetronUniversity of FloridaNULLCompleted18 Years70 YearsAll109United States

240. Phenylketonuria    [ 125 clinical trials,   95 drugs,   (DrugBank: 11 drugs),   1 drug target gene,   5 drug target pathways]
Searched query = "Phenylketonuria", "PKU", "Phenylalanine hydroxylase deficiency", "PAH deficiency", "Tetrahydrobiopterin deficiency", "BH4 deficiency", "BH4 reactive hyper pheemia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 125 trial found
No.TrialIDDate_
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Date_
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Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
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agemin
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PhaseCountries
1NCT01465100
(ClinicalTrials.gov)
February 202120/10/2011Liver Cell Transplant for PhenylketonuriaHepatocyte Transplantation for PhenylketonuriaPhenylketonuriaRadiation: Preparative Radiation Therapy;Procedure: Hepatocyte Transplant;Drug: Immunosuppression;Other: Liver Evaluation;Behavioral: Neuro-psychological Assessment;Diagnostic Test: Whole body Phe oxidation testing;Procedure: Liver BiopsyIra FoxNULLRecruiting14 Years55 YearsAll10Phase 1;Phase 2United States