Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Synonym: CVS Health Non Drowsy Daytime Cold and Flu Relief And Nighttime Cold and Flu Relief Day and Night Twin Pack)		4件: Acetaminophen; Paracetamol; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2 Adenosine
(Synonym: Botanic Twenty Recharging Toner)		2件: Adenosine; Ginseng1件: D00045 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65
3 Allantoin
(Synonym: Botanic Twenty Recharging Toner)		1件: ALLANTOIN1件: D00121 --1件: 36
4 Amlodipine
(Synonym: Twynsta)		1件: AMLODIPINE1件: D07450 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 13, 51, 67, 298
5 Ascorbic acid
(Synonym: Twin Ultra Liquid Orange Flavor)		4件: Acidum ascorbicum; ASCORBIC ACID; Iron; Vitamin C1件: D00018 --8件: 10, 97, 192, 206, 210, 211, 212, 298
6 Beta carotene
(Synonym: Twin Opti Pwr)		3件: Beta carotene; Beta-Carotene; BETACAROTENE1件: D03101 --2件: 13, 96
7 Biotin
(Synonym: Twin Opti Pwr)		4件: Biotin; Biotina; D-BIOTIN; Vitamin B71件: D00029 --5件: 2, 8, 10, 13, 20
8 Burosumab
(Synonym: burosumab-twza)		1件: Burosumab1件: D10913 (Name: Burosumab-twza)1件: FGF23 💬11件: Breast cancer, Calcium signaling pathway, Gastric cancer, MAPK signaling pathway, Melanoma, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton 💬1件: 238
9 Calcium
(Synonym: Twin Opti Pwr)		2件: Calcio; Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299
10 Cholecalciferol
(Synonym: Twin Opti Pwr)		5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D31件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬24件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
11 Choline
(Synonym: Twin Opti Pwr)		1件: Choline1件: D07690 --4件: 93, 171, 193, 299
12 Chromium
(Synonym: Twin Ultra Liquid Orange Flavor)		1件: Chromium---1件: 46
13 Copper
(Synonym: Twin Opti Pwr)		2件: Copper; Nicotinamide---4件: 2, 169, 170, 171
14 Cyanocobalamin
(Synonym: Twin Opti Pwr)		2件: Cianocobalamina; Vitamin B124件: D00166 ,
D03615 ,
D03616 ,
D03617 		--5件: 6, 13, 201, 229, 299
15 Dextromethorphan
(Synonym: Twkof Children)		4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta1件: D03742 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
16 Doconexent
(Synonym: Tricare Prenatal Twist-off DHA Soft Quick Dissolve)		2件: Docosahexaenoic acid; Docosahexanoic Acid---10件: 6, 46, 48, 49, 90, 94, 113, 240, 299, 301
17 Epinephrine
(Synonym: Twinject)		3件: Epinephrine; Lidocaine; Xylocaine1件: D00095 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 46, 70, 96
18 Ethanol
(Synonym: Health And Beyond Instant Hand Sanitizer Twin Pack Twin Pack)		3件: Alcohol; Ethanol; PREDNISONE1件: D06542 --5件: 58, 97, 279, 280, 298
19 Ethinylestradiol
(Synonym: Twirla)		3件: Ethinyl estradiol; ETHINYLESTRADIOL; Ortho-Novum 7771件: D00554 1件: ESR1 💬9件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬4件: 13, 46, 49, 299
20 Folic acid
(Synonym: Twin Opti Pwr)		5件: Acide folique; Folate; Folic acid; Multivitamin; NICOTINAMIDE1件: D00070 --6件: 6, 41, 46, 49, 84, 296
21 Glycerin
(Synonym: CVS Moisturizing Lubricating Eye Twin Pack)		2件: Bee venom; Glycerol1件: D00028 --5件: 6, 13, 79, 316, 317
22 Hepatitis A Vaccine
(Synonym: Twinrix Junior)		3件: Epaxal; Havrix; Hepatitis A Vaccine---3件: 46, 96, 97
23 Hepatitis B Vaccine (Recombinant)
(Synonym: Twinrix Paediatric)		3件: Fendrix; HBVAXPRO; Hepatitis B Vaccine---1件: 46
24 Hyaluronic acid
(Synonym: ELDEEN AGE TWENTY ONE MifitPatch and Serum)		2件: Hyaluronate; Hyaluronic acid1件: D08043 --6件: 46, 53, 70, 97, 226, 231
25 Icosapent
(Synonym: Tricare Prenatal Twist-off DHA Soft Quick Dissolve)		2件: Eicosapentaenoic acid; Icosapent1件: D08061 --11件: 8, 46, 48, 49, 96, 97, 113, 296, 297, 301, 338
26 Inositol
(Synonym: Twin Opti Pwr)		1件: Inositol1件: D08079 --2件: 96, 97
27 Iodine
(Synonym: Twin Opti Pwr)		2件: Iodine; Iodo1件: D00108 --2件: 28, 46
28 Levonorgestrel
(Synonym: Twirla)		1件: LEVONORGESTREL1件: D00950 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 13
29 Lidocaine
(Synonym: Arrow Two-lumen Jugular Catheterization Kit)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
30 Magnesium
(Synonym: Twin Opti Pwr)		1件: Magnesium---19件: 6, 11, 13, 46, 51, 63, 64, 70, 93, 97, 111, 166, 225, 235, 284, 291, 296, 297, 298
31 Mometasone furoate
(Synonym: Asmanex Twisthaler)		3件: Mometasone; Mometasone furoate; Nasonex1件: D00690 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 162
32 Nicotinamide
(Synonym: Twin Opti Pwr)		3件: Multivitamin; Niacinamide; NICOTINAMIDE1件: D00036 --10件: 2, 5, 6, 18, 49, 67, 97, 107, 162, 191
33 Omega-3 fatty acids
(Synonym: Tricare Prenatal Twist-off DHA Soft Quick Dissolve)		5件: Omega-3; Omega-3 fatty acid; Omega-3 fatty acids; OMEGA-3-ACID TRIGLYCERIDES; Phospholipids---8件: 13, 46, 49, 53, 66, 79, 96, 299
34 Petrolatum
(Synonym: Zinka Lemon Twist SPF 15 Lip Balm)		1件: Petrolatum1件: D05331 --1件: 158
35 Phenylephrine
(Synonym: Twkof Children)		1件: Phenylephrine1件: D08365 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
36 Potassium
(Synonym: Twin Opti Pwr)		1件: Potassium1件: D08403 --13件: 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235
37 Propylene glycol
(Synonym: Walgreens Lubricant Eye Drops High Performance 15mL and twin pack)		1件: Propylene glycol1件: D00078 --1件: 51
38 Pyridoxine
(Synonym: Twin Ultra Liquid Orange Flavor)		2件: Pyridoxine; Vitamin B61件: D08454 --5件: 6, 93, 145, 206, 320
39 Riboflavin
(Synonym: Twin Ultra Liquid Grape Flavor)		2件: Riboflavin; Vitamin B21件: D00050 --7件: 38, 46, 96, 97, 162, 168, 265
40 Salicylic acid
(Synonym: Two Step Jelly Mask - Brightening and Nutrition)		2件: 2-Hydroxybenzoic acid; Salicylic acid1件: D00097 --1件: 97
41 Selenium
(Synonym: Twin Opti Pwr)		1件: Selenium---4件: 13, 96, 278, 298
42 Sodium bicarbonate
(Synonym: Ceo-two)		1件: Sodium Bicarbonate1件: D01203 --1件: 299
43 Sodium fluoride
(Synonym: GUM Crayola Anticavity Fluoride Tropical Twist)		1件: Sodium fluoride1件: D00943 --1件: 51
44 Telmisartan
(Synonym: Twynsta)		1件: Telmisartan1件: D00627 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 66, 67
45 Thiamine
(Synonym: Twin Ultra Liquid Grape Flavor)		2件: Thiamine; Vitamin B11件: D08580 --4件: 8, 93, 145, 265
46 Tretinoin
(Synonym: Twyneo)		5件: ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID1件: D00094 3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231
47 Vitamin E
(Synonym: Twin Opti Pwr)		2件: Alpha-tocopherol; Vitamin E1件: D02331 --12件: 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317
48 Zinc
(Synonym: Twin Opti Pwr)		3件: Nicotinamide; Wilzin; Zinc---4件: 2, 113, 171, 299
49 Zinc oxide
(Synonym: FACE IT Radiance Two Way Cake NB23)		1件: Zinc oxide1件: D01170 --1件: 156