Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 DHODH 1件: Pyrimidine metabolism D00749 Leflunomide 12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
2 DHODH 1件: Pyrimidine metabolism D10172 Teriflunomide 3件: 13, 25, 26
3 RRM1 1件: Pyrimidine metabolism D01370 Cladribine 3件: 11, 13, 94
4 RRM1 1件: Pyrimidine metabolism D03546 Clofarabine 5件: 19, 20, 60, 234, 326
5 RRM1 1件: Pyrimidine metabolism D07966 Fludarabine 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
6 RRM2 1件: Pyrimidine metabolism D00341 Hydroxyurea 8件: 3, 13, 19, 20, 65, 85, 86, 284
7 TYMS 1件: Pyrimidine metabolism D01244 Tegafur 1件: 46