Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 MAPK14 2件: VEGF signaling pathway, Yersinia infection D09639 Losmapimod 2件: 113, 222
2 MAPK14 2件: VEGF signaling pathway, Yersinia infection D10959 Neflamapimod 1件: 8
3 KDR 1件: VEGF signaling pathway D03218 Axitinib 1件: 34
4 KDR 1件: VEGF signaling pathway D08524 Sorafenib 2件: 34, 86
5 KDR 1件: VEGF signaling pathway D08552 Sunitinib 2件: 28, 34
6 KDR 1件: VEGF signaling pathway D08881 Cediranib 1件: 34
7 KDR 1件: VEGF signaling pathway D10062 Cabozantinib 1件: 34
8 KDR 1件: VEGF signaling pathway D10481 Nintedanib 5件: 51, 85, 89, 227, 228
9 KDR 1件: VEGF signaling pathway D11772 Tesevatinib 1件: 67
10 PIK3CA 3件: VEGF signaling pathway, Yersinia infection, Viral carcinogenesis D11011 Alpelisib 1件: 138
11 PIK3CA 3件: VEGF signaling pathway, Yersinia infection, Viral carcinogenesis D11158 Leniolisib 2件: 53, 65
12 PIK3CB 3件: VEGF signaling pathway, Yersinia infection, Viral carcinogenesis D11158 Leniolisib 2件: 53, 65
13 PIK3CD 3件: VEGF signaling pathway, Yersinia infection, Viral carcinogenesis D11158 Leniolisib 2件: 53, 65
14 PIK3CD 3件: VEGF signaling pathway, Yersinia infection, Viral carcinogenesis D11437 Parsaclisib 3件: 35, 53, 61
15 PPP3CA 2件: Wnt signaling pathway, VEGF signaling pathway D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
16 PPP3CA 2件: Wnt signaling pathway, VEGF signaling pathway D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
17 PPP3CA 2件: Wnt signaling pathway, VEGF signaling pathway D05480 Pimecrolimus 1件: 160
18 PPP3CA 2件: Wnt signaling pathway, VEGF signaling pathway D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
19 PPP3CA 2件: Wnt signaling pathway, VEGF signaling pathway D09033 Voclosporin 2件: 49, 222
20 PPP3CB 2件: Wnt signaling pathway, VEGF signaling pathway D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
21 PPP3CB 2件: Wnt signaling pathway, VEGF signaling pathway D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
22 PPP3CB 2件: Wnt signaling pathway, VEGF signaling pathway D05480 Pimecrolimus 1件: 160
23 PPP3CB 2件: Wnt signaling pathway, VEGF signaling pathway D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
24 PPP3CB 2件: Wnt signaling pathway, VEGF signaling pathway D09033 Voclosporin 2件: 49, 222
25 PPP3CC 2件: Wnt signaling pathway, VEGF signaling pathway D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
26 PPP3CC 2件: Wnt signaling pathway, VEGF signaling pathway D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
27 PPP3CC 2件: Wnt signaling pathway, VEGF signaling pathway D05480 Pimecrolimus 1件: 160
28 PPP3CC 2件: Wnt signaling pathway, VEGF signaling pathway D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
29 PPP3CC 2件: Wnt signaling pathway, VEGF signaling pathway D09033 Voclosporin 2件: 49, 222
30 PPP3R1 2件: Wnt signaling pathway, VEGF signaling pathway D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
31 PPP3R1 2件: Wnt signaling pathway, VEGF signaling pathway D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
32 PPP3R1 2件: Wnt signaling pathway, VEGF signaling pathway D05480 Pimecrolimus 1件: 160
33 PPP3R1 2件: Wnt signaling pathway, VEGF signaling pathway D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
34 PPP3R1 2件: Wnt signaling pathway, VEGF signaling pathway D09033 Voclosporin 2件: 49, 222
35 PPP3R2 2件: Wnt signaling pathway, VEGF signaling pathway D00107 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
36 PPP3R2 2件: Wnt signaling pathway, VEGF signaling pathway D00184 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
37 PPP3R2 2件: Wnt signaling pathway, VEGF signaling pathway D05480 Pimecrolimus 1件: 160
38 PPP3R2 2件: Wnt signaling pathway, VEGF signaling pathway D08556 Tacrolimus 34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
39 PPP3R2 2件: Wnt signaling pathway, VEGF signaling pathway D09033 Voclosporin 2件: 49, 222
40 PRKCB 2件: Wnt signaling pathway, VEGF signaling pathway D11935 Enzastaurin 1件: 168
41 MAPK11 2件: VEGF signaling pathway, Yersinia infection D09639 Losmapimod 2件: 113, 222
42 MAPK11 2件: VEGF signaling pathway, Yersinia infection D10959 Neflamapimod 1件: 8
43 MAPK13 2件: VEGF signaling pathway, Yersinia infection D09639 Losmapimod 2件: 113, 222
44 MAPK13 2件: VEGF signaling pathway, Yersinia infection D10959 Neflamapimod 1件: 8
45 MAP2K1 2件: VEGF signaling pathway, Yersinia infection D09666 Selumetinib 1件: 34
46 MAP2K1 2件: VEGF signaling pathway, Yersinia infection D10175 Trametinib 4件: 2, 34, 279, 280
47 MAP2K1 2件: VEGF signaling pathway, Yersinia infection D10405 Cobimetinib 1件: 280
48 MAP2K1 2件: VEGF signaling pathway, Yersinia infection D10604 Binimetinib 1件: 34
49 MAP2K1 2件: VEGF signaling pathway, Yersinia infection D11675 Mirdametinib 1件: 34
50 MAP2K2 2件: VEGF signaling pathway, Yersinia infection D09666 Selumetinib 1件: 34
51 MAP2K2 2件: VEGF signaling pathway, Yersinia infection D10175 Trametinib 4件: 2, 34, 279, 280
52 MAP2K2 2件: VEGF signaling pathway, Yersinia infection D10405 Cobimetinib 1件: 280
53 MAP2K2 2件: VEGF signaling pathway, Yersinia infection D10604 Binimetinib 1件: 34
54 MAP2K2 2件: VEGF signaling pathway, Yersinia infection D11675 Mirdametinib 1件: 34
55 PTGS2 1件: VEGF signaling pathway D00109 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
56 PTGS2 1件: VEGF signaling pathway D00118 Naproxen 4件: 13, 46, 107, 271
57 PTGS2 1件: VEGF signaling pathway D00120 Sulindac 1件: 206
58 PTGS2 1件: VEGF signaling pathway D00126 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
59 PTGS2 1件: VEGF signaling pathway D00130 Diflunisal 1件: 28
60 PTGS2 1件: VEGF signaling pathway D00132 Ketoprofen 1件: 46
61 PTGS2 1件: VEGF signaling pathway D00141 Indomethacin 3件: 225, 271, 298
62 PTGS2 1件: VEGF signaling pathway D00217 Acetaminophen 15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
63 PTGS2 1件: VEGF signaling pathway D00315 Etodolac 1件: 46
64 PTGS2 1件: VEGF signaling pathway D00330 Flurbiprofen 3件: 13, 21, 46
65 PTGS2 1件: VEGF signaling pathway D00428 Salsalate 1件: 5
66 PTGS2 1件: VEGF signaling pathway D00567 Celecoxib 10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
67 PTGS2 1件: VEGF signaling pathway D00568 Rofecoxib 1件: 46
68 PTGS2 1件: VEGF signaling pathway D00969 Meloxicam 4件: 46, 49, 271, 296
69 PTGS2 1件: VEGF signaling pathway D01049 Nimesulide 1件: 46
70 PTGS2 1件: VEGF signaling pathway D01183 Tolfenamic acid 1件: 5
71 PTGS2 1件: VEGF signaling pathway D01545 Aceclofenac 1件: 46
72 PTGS2 1件: VEGF signaling pathway D02709 Valdecoxib 1件: 46
73 PTGS2 1件: VEGF signaling pathway D03710 Etoricoxib 2件: 46, 271
74 PTGS2 1件: VEGF signaling pathway D03714 Lumiracoxib 1件: 46
75 PTGS2 1件: VEGF signaling pathway D03716 Parecoxib 2件: 46, 271
76 PTGS2 1件: VEGF signaling pathway D07816 Diclofenac 5件: 13, 34, 46, 78, 271
77 PTGS2 1件: VEGF signaling pathway D08104 Ketorolac 2件: 70, 226
78 PTGS2 1件: VEGF signaling pathway D08149 Loxoprofen 2件: 46, 271
79 RAF1 1件: VEGF signaling pathway D08524 Sorafenib 2件: 34, 86
80 MAPK12 2件: VEGF signaling pathway, Yersinia infection D09639 Losmapimod 2件: 113, 222
81 MAPK12 2件: VEGF signaling pathway, Yersinia infection D10959 Neflamapimod 1件: 8
82 SRC 3件: VEGF signaling pathway, Yersinia infection, Viral carcinogenesis D03252 Bosutinib 2件: 2, 67
83 SRC 3件: VEGF signaling pathway, Yersinia infection, Viral carcinogenesis D03658 Dasatinib 2件: 51, 85
84 SRC 3件: VEGF signaling pathway, Yersinia infection, Viral carcinogenesis D06414 Dasatinib 2件: 51, 85
85 SRC 3件: VEGF signaling pathway, Yersinia infection, Viral carcinogenesis D09664 Saracatinib 3件: 6, 89, 272
86 VEGFA 1件: VEGF signaling pathway D05697 Ranibizumab 4件: 34, 166, 227, 301
87 VEGFA 1件: VEGF signaling pathway D06409 Bevacizumab 6件: 13, 34, 85, 87, 227, 280
88 VEGFA 1件: VEGF signaling pathway D09574 Aflibercept 2件: 90, 166
89 CASP9 2件: VEGF signaling pathway, Viral myocarditis D11195 Rimiducid 6件: 19, 60, 65, 284, 285, 326