Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CHRM3 1件: Taste transduction D00113 Atropine 2件: 2, 299
2 CHRM3 1件: Taste transduction D00138 Scopolamine 1件: 2
3 CHRM3 1件: Taste transduction D00270 Chlorpromazine 1件: 254
4 CHRM3 1件: Taste transduction D00397 Tropicamide 1件: 6
5 CHRM3 1件: Taste transduction D00465 Oxybutynin 3件: 6, 13, 53
6 CHRM3 1件: Taste transduction D00525 Pilocarpine 3件: 6, 53, 299
7 CHRM3 1件: Taste transduction D00646 Tolterodine 2件: 17, 53
8 CHRM3 1件: Taste transduction D03654 Darifenacin 2件: 6, 13
9 CHRM3 1件: Taste transduction D07226 Fesoterodine 1件: 6
10 CHRM3 1件: Taste transduction D07667 Cevimeline 1件: 53
11 CHRM3 1件: Taste transduction D08441 Propiverine 1件: 226
12 CHRM3 1件: Taste transduction D08522 Solifenacin 3件: 6, 13, 53
13 CHRM3 1件: Taste transduction D08638 Trihexyphenidyl 2件: 5, 6
14 CHRM3 1件: Taste transduction D11383 Blarcamesine 1件: 156
15 HTR3C 1件: Taste transduction D00283 Clozapine 1件: 6
16 HTR3C 1件: Taste transduction D00456 Ondansetron 3件: 6, 97, 107
17 HTR3C 1件: Taste transduction D07867 Dolasetron 1件: 46
18 HTR3C 1件: Taste transduction D10184 Vortioxetine 1件: 6
19 HTR3D 1件: Taste transduction D00283 Clozapine 1件: 6
20 HTR3D 1件: Taste transduction D00456 Ondansetron 3件: 6, 97, 107
21 HTR3D 1件: Taste transduction D07867 Dolasetron 1件: 46
22 HTR3D 1件: Taste transduction D10184 Vortioxetine 1件: 6
23 GABBR1 1件: Taste transduction D00241 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206
24 GABBR1 1件: Taste transduction D08861 Arbaclofen Placarbil 1件: 13
25 GABBR1 1件: Taste transduction D09791 Arbaclofen 2件: 13, 206
26 GABBR1 1件: Taste transduction D12240 Valiloxybate 1件: 6
27 GABRA1 1件: Taste transduction D00225 Alprazolam 2件: 8, 75
28 GABRA1 1件: Taste transduction D00280 Clonazepam 1件: 6
29 GABRA1 1件: Taste transduction D00293 Diazepam 3件: 46, 155, 298
30 GABRA1 1件: Taste transduction D00365 Lorazepam 1件: 36
31 GABRA1 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
32 GABRA1 1件: Taste transduction D00548 Etomidate 1件: 6
33 GABRA1 1件: Taste transduction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
34 GABRA1 1件: Taste transduction D00550 Midazolam 12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
35 GABRA1 1件: Taste transduction D00697 Flumazenil 5件: 6, 13, 17, 18, 206
36 GABRA1 1件: Taste transduction D01253 Clobazam 2件: 140, 144
37 GABRA1 1件: Taste transduction D01372 Zopiclone 1件: 6
38 GABRA1 1件: Taste transduction D02624 Eszopiclone 3件: 6, 13, 46
39 GABRA1 1件: Taste transduction D04282 Gaboxadol 2件: 201, 206
40 GABRA1 1件: Taste transduction D04300 Ganaxolone 4件: 145, 152, 158, 206
41 GABRA1 1件: Taste transduction D07784 Delorazepam 3件: 6, 46, 97
42 GABRA1 1件: Taste transduction D08690 Zolpidem 3件: 5, 6, 46
43 GABRA1 1件: Taste transduction D11149 Brexanolone 1件: 205
44 GABRA2 1件: Taste transduction D00225 Alprazolam 2件: 8, 75
45 GABRA2 1件: Taste transduction D00280 Clonazepam 1件: 6
46 GABRA2 1件: Taste transduction D00293 Diazepam 3件: 46, 155, 298
47 GABRA2 1件: Taste transduction D00365 Lorazepam 1件: 36
48 GABRA2 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
49 GABRA2 1件: Taste transduction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
50 GABRA2 1件: Taste transduction D00550 Midazolam 12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
51 GABRA2 1件: Taste transduction D00697 Flumazenil 5件: 6, 13, 17, 18, 206
52 GABRA2 1件: Taste transduction D01253 Clobazam 2件: 140, 144
53 GABRA2 1件: Taste transduction D01372 Zopiclone 1件: 6
54 GABRA2 1件: Taste transduction D02624 Eszopiclone 3件: 6, 13, 46
55 GABRA2 1件: Taste transduction D04282 Gaboxadol 2件: 201, 206
56 GABRA2 1件: Taste transduction D04300 Ganaxolone 4件: 145, 152, 158, 206
57 GABRA2 1件: Taste transduction D07784 Delorazepam 3件: 6, 46, 97
58 GABRA2 1件: Taste transduction D08690 Zolpidem 3件: 5, 6, 46
59 GABRA2 1件: Taste transduction D11149 Brexanolone 1件: 205
60 GABRA3 1件: Taste transduction D00225 Alprazolam 2件: 8, 75
61 GABRA3 1件: Taste transduction D00280 Clonazepam 1件: 6
62 GABRA3 1件: Taste transduction D00293 Diazepam 3件: 46, 155, 298
63 GABRA3 1件: Taste transduction D00365 Lorazepam 1件: 36
64 GABRA3 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
65 GABRA3 1件: Taste transduction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
66 GABRA3 1件: Taste transduction D00550 Midazolam 12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
67 GABRA3 1件: Taste transduction D00697 Flumazenil 5件: 6, 13, 17, 18, 206
68 GABRA3 1件: Taste transduction D01253 Clobazam 2件: 140, 144
69 GABRA3 1件: Taste transduction D01372 Zopiclone 1件: 6
70 GABRA3 1件: Taste transduction D02624 Eszopiclone 3件: 6, 13, 46
71 GABRA3 1件: Taste transduction D04282 Gaboxadol 2件: 201, 206
72 GABRA3 1件: Taste transduction D04300 Ganaxolone 4件: 145, 152, 158, 206
73 GABRA3 1件: Taste transduction D07784 Delorazepam 3件: 6, 46, 97
74 GABRA3 1件: Taste transduction D08690 Zolpidem 3件: 5, 6, 46
75 GABRA3 1件: Taste transduction D11149 Brexanolone 1件: 205
76 GABRA4 1件: Taste transduction D00225 Alprazolam 2件: 8, 75
77 GABRA4 1件: Taste transduction D00280 Clonazepam 1件: 6
78 GABRA4 1件: Taste transduction D00293 Diazepam 3件: 46, 155, 298
79 GABRA4 1件: Taste transduction D00365 Lorazepam 1件: 36
80 GABRA4 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
81 GABRA4 1件: Taste transduction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
82 GABRA4 1件: Taste transduction D00550 Midazolam 12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
83 GABRA4 1件: Taste transduction D00697 Flumazenil 5件: 6, 13, 17, 18, 206
84 GABRA4 1件: Taste transduction D01253 Clobazam 2件: 140, 144
85 GABRA4 1件: Taste transduction D01372 Zopiclone 1件: 6
86 GABRA4 1件: Taste transduction D02624 Eszopiclone 3件: 6, 13, 46
87 GABRA4 1件: Taste transduction D04282 Gaboxadol 2件: 201, 206
88 GABRA4 1件: Taste transduction D04300 Ganaxolone 4件: 145, 152, 158, 206
89 GABRA4 1件: Taste transduction D07784 Delorazepam 3件: 6, 46, 97
90 GABRA4 1件: Taste transduction D08690 Zolpidem 3件: 5, 6, 46
91 GABRA4 1件: Taste transduction D11149 Brexanolone 1件: 205
92 GABRA5 1件: Taste transduction D00225 Alprazolam 2件: 8, 75
93 GABRA5 1件: Taste transduction D00280 Clonazepam 1件: 6
94 GABRA5 1件: Taste transduction D00293 Diazepam 3件: 46, 155, 298
95 GABRA5 1件: Taste transduction D00365 Lorazepam 1件: 36
96 GABRA5 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
97 GABRA5 1件: Taste transduction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
98 GABRA5 1件: Taste transduction D00550 Midazolam 12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
99 GABRA5 1件: Taste transduction D00697 Flumazenil 5件: 6, 13, 17, 18, 206
100 GABRA5 1件: Taste transduction D01253 Clobazam 2件: 140, 144
101 GABRA5 1件: Taste transduction D01372 Zopiclone 1件: 6
102 GABRA5 1件: Taste transduction D02624 Eszopiclone 3件: 6, 13, 46
103 GABRA5 1件: Taste transduction D04282 Gaboxadol 2件: 201, 206
104 GABRA5 1件: Taste transduction D04300 Ganaxolone 4件: 145, 152, 158, 206
105 GABRA5 1件: Taste transduction D07784 Delorazepam 3件: 6, 46, 97
106 GABRA5 1件: Taste transduction D08690 Zolpidem 3件: 5, 6, 46
107 GABRA5 1件: Taste transduction D11149 Brexanolone 1件: 205
108 GABRA6 1件: Taste transduction D00225 Alprazolam 2件: 8, 75
109 GABRA6 1件: Taste transduction D00280 Clonazepam 1件: 6
110 GABRA6 1件: Taste transduction D00293 Diazepam 3件: 46, 155, 298
111 GABRA6 1件: Taste transduction D00365 Lorazepam 1件: 36
112 GABRA6 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
113 GABRA6 1件: Taste transduction D00549 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296
114 GABRA6 1件: Taste transduction D00550 Midazolam 12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
115 GABRA6 1件: Taste transduction D00697 Flumazenil 5件: 6, 13, 17, 18, 206
116 GABRA6 1件: Taste transduction D01253 Clobazam 2件: 140, 144
117 GABRA6 1件: Taste transduction D01372 Zopiclone 1件: 6
118 GABRA6 1件: Taste transduction D02624 Eszopiclone 3件: 6, 13, 46
119 GABRA6 1件: Taste transduction D04282 Gaboxadol 2件: 201, 206
120 GABRA6 1件: Taste transduction D04300 Ganaxolone 4件: 145, 152, 158, 206
121 GABRA6 1件: Taste transduction D07784 Delorazepam 3件: 6, 46, 97
122 GABRA6 1件: Taste transduction D08690 Zolpidem 3件: 5, 6, 46
123 GABRA6 1件: Taste transduction D11149 Brexanolone 1件: 205
124 HTR3E 1件: Taste transduction D00283 Clozapine 1件: 6
125 HTR3E 1件: Taste transduction D00456 Ondansetron 3件: 6, 97, 107
126 HTR3E 1件: Taste transduction D07867 Dolasetron 1件: 46
127 HTR3E 1件: Taste transduction D10184 Vortioxetine 1件: 6
128 HTR1A 1件: Taste transduction D01164 Aripiprazole 2件: 6, 206
129 HTR1A 1件: Taste transduction D07593 Buspirone 2件: 6, 51
130 HTR1A 1件: Taste transduction D09397 Pardoprunox 1件: 6
131 HTR1A 1件: Taste transduction D09997 Cariprazine 1件: 21
132 HTR1A 1件: Taste transduction D10184 Vortioxetine 1件: 6
133 HTR1B 1件: Taste transduction D00415 Zolmitriptan 1件: 6
134 HTR1D 1件: Taste transduction D00415 Zolmitriptan 1件: 6
135 HTR1D 1件: Taste transduction D07945 Fenfluramine 4件: 140, 144, 145, 149
136 HTR3A 1件: Taste transduction D00274 Cisapride 1件: 13
137 HTR3A 1件: Taste transduction D00283 Clozapine 1件: 6
138 HTR3A 1件: Taste transduction D00456 Ondansetron 3件: 6, 97, 107
139 HTR3A 1件: Taste transduction D02092 Cisapride 1件: 13
140 HTR3A 1件: Taste transduction D07867 Dolasetron 1件: 46
141 HTR3A 1件: Taste transduction D10184 Vortioxetine 1件: 6
142 P2RX3 1件: Taste transduction D11349 Gefapixant 2件: 85, 226
143 PDE1A 1件: Taste transduction D00227 Aminophylline 1件: 63
144 PDE1A 1件: Taste transduction D00371 Theophylline 2件: 236, 299
145 PDE1A 1件: Taste transduction D06103 Theophylline 2件: 236, 299
146 PDE1A 1件: Taste transduction D07546 Bucladesine 1件: 246
147 PDE1A 1件: Taste transduction D07961 Flavoxate 1件: 226
148 PDE1C 1件: Taste transduction D00227 Aminophylline 1件: 63
149 PDE1C 1件: Taste transduction D00371 Theophylline 2件: 236, 299
150 PDE1C 1件: Taste transduction D06103 Theophylline 2件: 236, 299
151 PDE1C 1件: Taste transduction D07546 Bucladesine 1件: 246
152 PDE1C 1件: Taste transduction D07961 Flavoxate 1件: 226
153 PDE1B 1件: Taste transduction D00227 Aminophylline 1件: 63
154 PDE1B 1件: Taste transduction D00371 Theophylline 2件: 236, 299
155 PDE1B 1件: Taste transduction D00528 Caffeine 8件: 2, 6, 21, 46, 78, 96, 97, 265
156 PDE1B 1件: Taste transduction D01453 Caffeine 8件: 2, 6, 21, 46, 78, 96, 97, 265
157 PDE1B 1件: Taste transduction D06103 Theophylline 2件: 236, 299
158 PDE1B 1件: Taste transduction D07546 Bucladesine 1件: 246
159 PDE1B 1件: Taste transduction D07961 Flavoxate 1件: 226
160 SCN2A 1件: Taste transduction D00252 Carbamazepine 3件: 6, 13, 231
161 SCN2A 1件: Taste transduction D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
162 SCN2A 1件: Taste transduction D00358 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
163 SCN2A 1件: Taste transduction D00512 Phenytoin 1件: 13
164 SCN2A 1件: Taste transduction D00533 Oxcarbazepine 1件: 13
165 SCN2A 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
166 SCN2A 1件: Taste transduction D00538 Zonisamide 1件: 6
167 SCN2A 1件: Taste transduction D02910 Amiodarone 2件: 28, 127
168 SCN2A 1件: Taste transduction D03492 Cibenzoline 1件: 58
169 SCN2A 1件: Taste transduction D05775 Rufinamide 1件: 144
170 SCN2A 1件: Taste transduction D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
171 SCN2A 1件: Taste transduction D07962 Flecainide 1件: 6
172 SCN2A 1件: Taste transduction D08116 Levobupivacaine 1件: 46
173 SCN2A 1件: Taste transduction D08127 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
174 SCN2A 1件: Taste transduction D08215 Mexiletine 5件: 1, 2, 10, 113, 114
175 SCN2A 1件: Taste transduction D08319 Oxybuprocaine 1件: 6
176 SCN2A 1件: Taste transduction D08458 Quinidine 3件: 2, 8, 13
177 SCN2A 1件: Taste transduction D08490 Ropivacaine 4件: 22, 36, 46, 70
178 SCN2A 1件: Taste transduction D11155 Eleclazine 1件: 58
179 SCN3A 1件: Taste transduction D00252 Carbamazepine 3件: 6, 13, 231
180 SCN3A 1件: Taste transduction D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
181 SCN3A 1件: Taste transduction D00358 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
182 SCN3A 1件: Taste transduction D00512 Phenytoin 1件: 13
183 SCN3A 1件: Taste transduction D00533 Oxcarbazepine 1件: 13
184 SCN3A 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
185 SCN3A 1件: Taste transduction D00538 Zonisamide 1件: 6
186 SCN3A 1件: Taste transduction D02910 Amiodarone 2件: 28, 127
187 SCN3A 1件: Taste transduction D03492 Cibenzoline 1件: 58
188 SCN3A 1件: Taste transduction D05775 Rufinamide 1件: 144
189 SCN3A 1件: Taste transduction D07299 Lacosamide 4件: 2, 46, 149, 298
190 SCN3A 1件: Taste transduction D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
191 SCN3A 1件: Taste transduction D07962 Flecainide 1件: 6
192 SCN3A 1件: Taste transduction D08116 Levobupivacaine 1件: 46
193 SCN3A 1件: Taste transduction D08127 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
194 SCN3A 1件: Taste transduction D08215 Mexiletine 5件: 1, 2, 10, 113, 114
195 SCN3A 1件: Taste transduction D08319 Oxybuprocaine 1件: 6
196 SCN3A 1件: Taste transduction D08458 Quinidine 3件: 2, 8, 13
197 SCN3A 1件: Taste transduction D08490 Ropivacaine 4件: 22, 36, 46, 70
198 SCN3A 1件: Taste transduction D11155 Eleclazine 1件: 58
199 SCN9A 1件: Taste transduction D00252 Carbamazepine 3件: 6, 13, 231
200 SCN9A 1件: Taste transduction D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
201 SCN9A 1件: Taste transduction D00358 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
202 SCN9A 1件: Taste transduction D00512 Phenytoin 1件: 13
203 SCN9A 1件: Taste transduction D00533 Oxcarbazepine 1件: 13
204 SCN9A 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
205 SCN9A 1件: Taste transduction D00538 Zonisamide 1件: 6
206 SCN9A 1件: Taste transduction D02910 Amiodarone 2件: 28, 127
207 SCN9A 1件: Taste transduction D03492 Cibenzoline 1件: 58
208 SCN9A 1件: Taste transduction D05775 Rufinamide 1件: 144
209 SCN9A 1件: Taste transduction D07299 Lacosamide 4件: 2, 46, 149, 298
210 SCN9A 1件: Taste transduction D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
211 SCN9A 1件: Taste transduction D07962 Flecainide 1件: 6
212 SCN9A 1件: Taste transduction D08116 Levobupivacaine 1件: 46
213 SCN9A 1件: Taste transduction D08127 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
214 SCN9A 1件: Taste transduction D08215 Mexiletine 5件: 1, 2, 10, 113, 114
215 SCN9A 1件: Taste transduction D08319 Oxybuprocaine 1件: 6
216 SCN9A 1件: Taste transduction D08458 Quinidine 3件: 2, 8, 13
217 SCN9A 1件: Taste transduction D08490 Ropivacaine 4件: 22, 36, 46, 70
218 SCN9A 1件: Taste transduction D11155 Eleclazine 1件: 58
219 SCNN1A 1件: Taste transduction D07447 Amiloride 4件: 13, 67, 225, 299
220 SCNN1B 1件: Taste transduction D07447 Amiloride 4件: 13, 67, 225, 299
221 SCNN1G 1件: Taste transduction D07447 Amiloride 4件: 13, 67, 225, 299
222 CACNA1C 3件: Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D00349 Isradipine 1件: 6
223 CACNA1C 3件: Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D00437 Nifedipine 2件: 50, 81
224 CACNA1C 3件: Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
225 CACNA1C 3件: Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D01173 Cilnidipine 1件: 67
226 CACNA1C 3件: Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D01908 Nilvadipine 1件: 90
227 CACNA1C 3件: Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D02356 Verapamil 4件: 58, 96, 140, 167
228 CACNA1C 3件: Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D07450 Amlodipine 4件: 13, 51, 67, 298
229 CACNA1C 3件: Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D07845 Diltiazem 3件: 51, 58, 86
230 CACNA1C 3件: Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D08270 Nicardipine 2件: 70, 86
231 CACNA1C 3件: Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D08340 Perhexiline 2件: 58, 272
232 CACNA1C 3件: Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D08441 Propiverine 1件: 226
233 TAS1R2 1件: Taste transduction D02381 Aspartame 4件: 6, 13, 67, 86
234 TAS1R3 1件: Taste transduction D02381 Aspartame 4件: 6, 13, 67, 86
235 HTR3B 1件: Taste transduction D00283 Clozapine 1件: 6
236 HTR3B 1件: Taste transduction D00456 Ondansetron 3件: 6, 97, 107
237 HTR3B 1件: Taste transduction D07867 Dolasetron 1件: 46
238 HTR3B 1件: Taste transduction D10184 Vortioxetine 1件: 6
239 GABBR2 1件: Taste transduction D00241 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206
240 GABBR2 1件: Taste transduction D08861 Arbaclofen Placarbil 1件: 13
241 GABBR2 1件: Taste transduction D09791 Arbaclofen 2件: 13, 206
242 GABBR2 1件: Taste transduction D12240 Valiloxybate 1件: 6