Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 2 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
CHRM1 3件: CHRM1, CHRM3, CHRM5 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 3 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
ALAS1 1件: ALAS1 💬 |
D11702 D11702 💬 |
Givosiran | 254 1件: 254 💬 |
| 4 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
ALAS1 2件: ALAS1, ALAS2 💬 |
D10003 D10003 💬 |
Hemin | 254 1件: 254 💬 |
| 5 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CHRM1 8件: CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 6 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
HRH2 1件: HRH2 💬 |
D00295 D00295 💬 |
Cimetidine | 002 2件: 2 , 254 💬 |
| 7 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CHRM1 3件: CHRM1, CHRM2, DRD2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 8 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 9 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
HMOX1 1件: HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 10 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 11 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 12 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 13 | Ferroptosis 💬 Related to 2 target genes, 2 drugs (DrugBank) and 2 diseases in DDrare |
HMOX1 1件: HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 14 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
HMOX1 1件: HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 15 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 4件: DRD2, HTR2A, HTR2B, HTR2C 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 16 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 17 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
HRH2 1件: HRH2 💬 |
D00295 D00295 💬 |
Cimetidine | 002 2件: 2 , 254 💬 |
| 18 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
ALAS1 1件: ALAS1 💬 |
D11702 D11702 💬 |
Givosiran | 254 1件: 254 💬 |
| 19 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
ALAS1 2件: ALAS1, ALAS2 💬 |
D10003 D10003 💬 |
Hemin | 254 1件: 254 💬 |
| 20 | Hepatocellular carcinoma 💬 Related to 21 target genes, 31 drugs (DrugBank) and 57 diseases in DDrare |
HMOX1 1件: HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 21 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
HMOX1 1件: HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 22 | Inflammatory mediator regulation of TRP channels 💬 Related to 23 target genes, 43 drugs (DrugBank) and 59 diseases in DDrare |
HRH1 4件: HRH1, HTR2A, HTR2B, HTR2C 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 23 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 24 | Melanogenesis 💬 Related to 7 target genes, 16 drugs (DrugBank) and 29 diseases in DDrare |
MC1R 1件: MC1R 💬 |
D10511 D10511 💬 |
Afamelanotide | 159 3件: 159, 161, 254 💬 |
| 25 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ALAS1 1件: ALAS1 💬 |
D11702 D11702 💬 |
Givosiran | 254 1件: 254 💬 |
| 26 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ALAS1 2件: ALAS1, ALAS2 💬 |
D10003 D10003 💬 |
Hemin | 254 1件: 254 💬 |
| 27 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMOX1 2件: HMOX1, HMOX2 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 28 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
HMOX1 1件: HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 29 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 41 diseases in DDrare |
HMOX1 2件: HMOX1, HMOX2 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 30 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRA2A 13件: ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 31 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
HRH2 1件: HRH2 💬 |
D00295 D00295 💬 |
Cimetidine | 002 2件: 2 , 254 💬 |
| 32 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
MC1R 1件: MC1R 💬 |
D10511 D10511 💬 |
Afamelanotide | 159 3件: 159, 161, 254 💬 |
| 33 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 34 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 35 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
HMOX1 1件: HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 36 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
CHRM1 3件: CHRM1, CHRM3, CHRM5 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 37 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 38 | Porphyrin metabolism 💬 Related to 5 target genes, 4 drugs (DrugBank) and 2 diseases in DDrare |
ALAS1 1件: ALAS1 💬 |
D11702 D11702 💬 |
Givosiran | 254 1件: 254 💬 |
| 39 | Porphyrin metabolism 💬 Related to 5 target genes, 4 drugs (DrugBank) and 2 diseases in DDrare |
ALAS1 2件: ALAS1, ALAS2 💬 |
D10003 D10003 💬 |
Hemin | 254 1件: 254 💬 |
| 40 | Porphyrin metabolism 💬 Related to 5 target genes, 4 drugs (DrugBank) and 2 diseases in DDrare |
HMOX1 2件: HMOX1, HMOX2 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 41 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 42 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 43 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 44 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
HTR2A 3件: HTR2A, HTR2B, HTR2C 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 45 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |