Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬 |
2 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D10540 D10540 💬 |
Abrilumab | 096 2件: 96, 97 💬 |
3 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06590 D06590 💬 |
Firategrast | 013 1件: 13 💬 |
4 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
5 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 3件: 94, 96, 97 💬 |
6 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
ITGAL 1件: ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
7 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 2件: 113, 222 💬 |
8 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 1件: 8 💬 |
9 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
PIK3CA 1件: PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 1件: 138 💬 |
10 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
11 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
12 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
PRKCB 1件: PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 1件: 168 💬 |
13 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
14 | Leukocyte transendothelial migration 💬 Related to 13 target genes, 14 drugs (DrugBank) and 30 diseases in DDrare |
ROCK2 1件: ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 2件: 51, 85 💬 |