Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Parathyroid hormone synthesis, secretion and action 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
2 Parathyroid hormone synthesis, secretion and action 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
3 Parathyroid hormone synthesis, secretion and action 💬
2件: BRAF, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
4 Parathyroid hormone synthesis, secretion and action 💬
1件: CASR 💬 D03504 💬 Cinacalcet 1件: 238 💬
5 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 D03455 💬 Cetuximab 2件: 51, 86 💬
6 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
7 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
8 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
9 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
10 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 D08950 💬 Neratinib 1件: 34 💬
11 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 D11772 💬 Tesevatinib 1件: 67 💬
12 Parathyroid hormone synthesis, secretion and action 💬
1件: FGF23 💬 D10913 💬 Burosumab 1件: 238 💬
13 Parathyroid hormone synthesis, secretion and action 💬
1件: FGFR1 💬 D11589 💬 Infigratinib 1件: 276 💬
14 Parathyroid hormone synthesis, secretion and action 💬
1件: FGFR1 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
15 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 D10604 💬 Binimetinib 1件: 34 💬
16 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 D10405 💬 Cobimetinib 1件: 280 💬
17 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 D11675 💬 Mirdametinib 1件: 34 💬
18 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 D09666 💬 Selumetinib 1件: 34 💬
19 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
20 Parathyroid hormone synthesis, secretion and action 💬
1件: MMP13 💬 D08859 💬 Apratastat 1件: 46 💬
21 Parathyroid hormone synthesis, secretion and action 💬
1件: PDE4A 💬 D00302 💬 Dipyridamole 6件: 46, 49, 51, 66, 96, 224 💬
22 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 D00227 💬 Aminophylline 1件: 63 💬
23 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 D08860 💬 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271 💬
24 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 D07546 💬 Bucladesine 1件: 246 💬
25 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 D00528 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
26 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 D01453 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
27 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 D07961 💬 Flavoxate 1件: 226 💬
28 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 D01385 💬 Ibudilast 2件:  2 , 13 💬
29 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 D05744 💬 Roflumilast 4件: 84, 97, 206, 299 💬
30 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 D01783 💬 Rolipram 2件:  8 , 13 💬
31 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 D00371 💬 Theophylline 2件: 236, 299 💬
32 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 D06103 💬 Theophylline 2件: 236, 299 💬
33 Parathyroid hormone synthesis, secretion and action 💬
1件: PDE4D 💬 D12173 💬 Zatolmilast 1件: 206 💬
34 Parathyroid hormone synthesis, secretion and action 💬
1件: PRKCB 💬 D11935 💬 Enzastaurin 1件: 168 💬
35 Parathyroid hormone synthesis, secretion and action 💬
1件: PTH1R 💬 D05364 💬 Parathyroid hormone 4件: 65, 70, 235, 326 💬
36 Parathyroid hormone synthesis, secretion and action 💬
1件: PTH1R 💬 D06078 💬 Teriparatide 7件: 46, 65, 68, 70, 71, 235, 274 💬
37 Parathyroid hormone synthesis, secretion and action 💬
3件: RXRA, RXRB, RXRG 💬 D02754 💬 Acitretin 1件: 37 💬
38 Parathyroid hormone synthesis, secretion and action 💬
3件: RXRA, RXRB, RXRG 💬 D02815 💬 Alitretinoin 1件: 49 💬
39 Parathyroid hormone synthesis, secretion and action 💬
3件: RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene 2件: 13, 75 💬
40 Parathyroid hormone synthesis, secretion and action 💬
1件: SOST 💬 D10156 💬 Romosozumab 1件: 274 💬
41 Parathyroid hormone synthesis, secretion and action 💬
1件: TNFSF11 💬 D03684 💬 Denosumab 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬
42 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 D01518 💬 Alfacalcidol 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
43 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 D00122 💬 Calcifediol 2件: 113, 299 💬
44 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 D01125 💬 Calcipotriol 2件: 36, 51 💬
45 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 D00129 💬 Calcitriol 9件: 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
46 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 D00188 💬 Cholecalciferol 24件:  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
47 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 D00299 💬 Dihydrotachysterol 2件:  6 , 85 💬
48 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 D07578 💬 Eldecalcitol 1件: 46 💬
49 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 D00187 💬 Ergocalciferol 6件: 46, 49, 84, 96, 97, 299 💬
50 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 D00930 💬 Paricalcitol 5件: 19, 66, 218, 238, 298 💬