Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Salicylic acid [1] Salicylic acid[2] 2-Hydroxybenzoic acid; Salicylic acid; --[1] 97
2 Cyclosporine
(Synonym: Sandimmune (TN))		[1] Cyclosporine (Synonym: Sandimmune Soft Gelatine Cap 25mg)[10] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; NEORAL; Restasis; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
3 Salsalate [1] Salsalate[1] Salsalate; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 5
4 Saquinavir [1] Saquinavir[1] Saquinavir; --[2] 86, 265
5 Stavudine
(Synonym: Sanilvudine (JAN))		[1] Stavudine (Synonym: Sanilvudine)[1] Stavudine; --[1] 265
6 Sulfasalazine
(Synonym: Salazosulfapyridine (JP18))		[1] Sulfasalazine (Synonym: Salicylazosulfapyridine)[3] Salazosulfapyridine; Salicylazosulfapyridine; SULFASALAZINE; --[6] 46, 86, 94, 107, 270, 271
7 Vigabatrin
(Synonym: Sabril (TN))		[1] Vigabatrin (Synonym: Sabril Pwr 2g/sachet)[2] SABRIL; VIGABATRIN; [1] ABAT 💬[7] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[2] 145, 158
8 Tolvaptan
(Synonym: Samsca (TN))		[1] Tolvaptan (Synonym: Samsca)[3] Jinarc; Samsca; Tolvaptan; [1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[4] 67, 72, 86, 225
9 Albuterol
(Synonym: Salbutamol)		[1] Salbutamol[3] Albuterol; Salbutamol; Ventolin; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[12] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299
10 Iron sucrose
(Synonym: Ferric oxide, saccharated)		[1] Iron sucrose (Synonym: Iron saccharate)[1] Iron sucrose; --[3] 62, 96, 97
11 Salmeterol [1] Salmeterol[1] Salmeterol; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 299
12 Sargramostim [1] Sargramostim[2] Leukine; Sargramostim; [1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[7] 6, 28, 60, 62, 96, 229, 285
13 Liraglutide
(Synonym: SAXENDA)		[1] Liraglutide (Synonym: Saxenda)[2] Liraglutide; Saxenda; [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 6, 75, 193
14 Green tea leaf
(Synonym: Saicha)		[1] Green tea leaf[4] Green Tea; Green Tea Extract; GREEN TEA LEAF; Tea Extract; --[4] 6, 17, 28, 46
15 Benazepril
(Synonym: Benazepril Sandoz (TN))		[1] Benazepril[1] Benazepril; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 49, 57, 218, 224
16 Folinic acid calcium salt pentahydrate [1] Leucovorin[2] Folinic acid; Leucovorin; --[4] 19, 46, 107, 320
17 Strontium ranelate
(Synonym: Ranelic acid strontium salt)		[1] Strontium ranelate[1] Strontium ranelate; --[1] 78
18 Sapropterin [1] Sapropterin[5] 6R-BH4; KUVAN; Sapropterin; SAPROPTERIN DIHYDROCHLORIDE; Tetrahydrobiopterin; --[5] 51, 86, 124, 240, 299
19 Zolpidem
(Synonym: Sanval (TN))		[1] Zolpidem[2] Zolpidem; Zolpidem Tartrate; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 5, 6, 46
20 Saxagliptin [1] Saxagliptin[1] Saxagliptin; [1] DPP4 💬[1] Protein digestion and absorption 💬[1] 299
21 Nabiximols
(Synonym: Sativex (TN))		[1] Nabiximols[1] Nabiximols; --[1] 13
22 Saracatinib [1] Saracatinib[1] Saracatinib; [2] ABL1,
SRC 💬		[49] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[3] 6, 89, 272
23 Safinamide [1] Safinamide[3] Safinamida; SAFINAMIDE; Xadago; [1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[2] 6, 17
24 Sarilumab [1] Sarilumab[4] Kevzara; REGN88; SAR153191; SARILUMAB; [1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[5] 41, 46, 84, 107, 271
25 Sacubitril [1] Sacubitril[2] Entresto; Sacubitril; [1] MME 💬[4] Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬[2] 58, 222
26 Calcium carbonate
(Synonym: Carbonic-13C acid, calcium salt)		[1] Calcium carbonate (Synonym: Actonel Sachet Kit)[3] Calcio carbonato; Calcium; Calcium Carbonate; --[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
27 Isatuximab
(Synonym: Sarclisa (TN))		[1] Isatuximab (Synonym: Sarclisa)[1] Isatuximab; [1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[3] 28, 61, 283
28 Satralizumab [1] Satralizumab[3] Enspryng; Sapelizumab; SATRALIZUMAB; [1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[3] 11, 13, 86
29 Anifrolumab
(Synonym: Saphnelo (TN))		[1] Anifrolumab (Synonym: Saphnelo)[1] Anifrolumab; [2] IFNAR1,
IFNAR2 💬		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[3] 46, 49, 53