Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 SCN1A [1] Dopaminergic synapse D00252 Carbamazepine [3] 6, 13, 231
2 SCN1A [1] Dopaminergic synapse D00354 Lamotrigine [5] 13, 34, 38, 114, 144
3 SCN1A [1] Dopaminergic synapse D00358 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
4 SCN1A [1] Dopaminergic synapse D00512 Phenytoin [1] 13
5 SCN1A [1] Dopaminergic synapse D00533 Oxcarbazepine [1] 13
6 SCN1A [1] Dopaminergic synapse D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
7 SCN1A [1] Dopaminergic synapse D00538 Zonisamide [1] 6
8 SCN1A [1] Dopaminergic synapse D02910 Amiodarone [2] 28, 127
9 SCN1A [1] Dopaminergic synapse D03492 Cibenzoline [1] 58
10 SCN1A [1] Dopaminergic synapse D05775 Rufinamide [1] 144
11 SCN1A [1] Dopaminergic synapse D07552 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298
12 SCN1A [1] Dopaminergic synapse D07962 Flecainide [1] 6
13 SCN1A [1] Dopaminergic synapse D08116 Levobupivacaine [1] 46
14 SCN1A [1] Dopaminergic synapse D08127 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
15 SCN1A [1] Dopaminergic synapse D08215 Mexiletine [5] 1, 2, 10, 113, 114
16 SCN1A [1] Dopaminergic synapse D08319 Oxybuprocaine [1] 6
17 SCN1A [1] Dopaminergic synapse D08458 Quinidine [3] 2, 8, 13
18 SCN1A [1] Dopaminergic synapse D08490 Ropivacaine [4] 22, 36, 46, 70
19 SCN1A [1] Dopaminergic synapse D11155 Eleclazine [1] 58