86. Pulmonary arterial hypertension Clinical trials / Disease details
Clinical trials : 1,205 / Drugs : 684 - (DrugBank : 124) / Drug target genes : 100 - Drug target pathways : 193
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | JPRN-UMIN000020386 | 1999/04/01 | 28/12/2015 | Acute Vasoreactivity Testing with Nicardipine in Patients with Pulmonary Arterial Hypertension | Acute Vasoreactivity Testing with Nicardipine in Patients with Pulmonary Arterial Hypertension - Acute Vasoreactivity Testing with Nicardipine in Patients with Pulmonary Arterial Hypertension | plumonary arterial hypertension | Nicardipine was administered by short-time continuous infusion (1 microg/kg/min for 5 min and 2 microg/kg/min for 5 min) followed by bolus injection (5 microg/kg). Hemodynamic responses were continuously measured using a right heart catheter.Hemodynamic responses were continuously measured before, during and after administration of nicardipine using an RHC. SaO2 (saturation of arterial blood) and SPAO2 (saturation of pulmonary arterial blood) were measured to calculate cardiac output every 5 minutes. | Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences | National Hospital Organization, Okayama Medical Center | Complete: follow-up complete | Not applicable | Not applicable | Male and Female | 100 | Not applicable | Japan |