Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [4] BRAF, FLT3, KIT, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
2 Acute myeloid leukemia 💬
 [1] KIT 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3 Acute myeloid leukemia 💬
 [1] KIT 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
4 Acute myeloid leukemia 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
5 Adherens junction 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
6 Adipocytokine signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
7 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
8 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
9 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
10 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
11 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
12 Adrenergic signaling in cardiomyocytes 💬
 [2] AGTR1, AGTR2 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
13 Adrenergic signaling in cardiomyocytes 💬
 [2] AGTR1, AGTR2 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
14 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
15 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
16 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 D00358 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
17 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 D08127 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
18 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
19 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
20 Alcoholic liver disease 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
21 Alcoholic liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
22 Alcoholism 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
23 Alcoholism 💬
 [1] DRD2 💬 D08132 💬 Lisuride [2]  6 , 86 💬
24 Alcoholism 💬
 [1] DRD2 💬 D01348 💬 Terguride [2] 51, 86 💬
25 Aldosterone synthesis and secretion 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
26 Aldosterone synthesis and secretion 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
27 Aldosterone synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
28 Aldosterone synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
29 Aldosterone-regulated sodium reabsorption 💬
 [1] NR3C2 💬 D00443 💬 Spironolactone [8] 46, 58, 67, 86, 113, 210, 218, 225 💬
30 Alzheimer disease 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
31 Alzheimer disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
32 Alzheimer disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
33 Alzheimer disease 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
34 Alzheimer disease 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
35 Alzheimer disease 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
36 Alzheimer disease 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
37 Amoebiasis 💬
 [2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
38 Amphetamine addiction 💬
 [2] CACNA1C, CACNA1D 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
39 Amphetamine addiction 💬
 [2] CACNA1C, CACNA1D 💬 D08270 💬 Nicardipine [2] 70, 86 💬
40 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
41 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
42 AMPK signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
43 AMPK signaling pathway 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
44 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
45 Amyotrophic lateral sclerosis 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
46 Amyotrophic lateral sclerosis 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
47 Apelin signaling pathway 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
48 Apelin signaling pathway 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
49 Apelin signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
50 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
51 Apelin signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
52 Apoptosis 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
53 Apoptosis 💬
 [2] PARP1, PARP2 💬 D09730 💬 Olaparib [2] 86, 285 💬
54 Apoptosis 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
55 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
56 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
57 Arrhythmogenic right ventricular cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
58 Arrhythmogenic right ventricular cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
59 Autophagy - animal 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
60 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
61 Autophagy - animal 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
62 Autophagy - other 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
63 Axon guidance 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
64 Axon guidance 💬
 [1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
65 Axon guidance 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
66 B cell receptor signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
67 Base excision repair 💬
 [2] PARP1, PARP2 💬 D09730 💬 Olaparib [2] 86, 285 💬
68 Bile secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
69 Bile secretion 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
70 Biosynthesis of cofactors 💬
 [2] NQO1, VKORC1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
71 Bladder cancer 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
72 Bladder cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
73 Breast cancer 💬
 [4] BRAF, FLT4, KIT, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
74 Breast cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
75 Breast cancer 💬
 [2] ESR1, ESR2 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
76 Breast cancer 💬
 [2] ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
77 Breast cancer 💬
 [1] KIT 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
78 Breast cancer 💬
 [1] KIT 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
79 Breast cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
80 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
81 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
82 C-type lectin receptor signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
83 Calcium signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
84 Calcium signaling pathway 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
85 Calcium signaling pathway 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
86 Calcium signaling pathway 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
87 Calcium signaling pathway 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
88 Calcium signaling pathway 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
89 Calcium signaling pathway 💬
 [1] AVPR1A 💬 D07748 💬 Conivaptan [1] 86 💬
90 Calcium signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
91 Calcium signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
92 Calcium signaling pathway 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
93 Calcium signaling pathway 💬
 [1] EDNRA 💬 D07171 💬 Sitaxentan [1] 86 💬
94 Calcium signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
95 Calcium signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
96 Calcium signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
97 Calcium signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
98 Calcium signaling pathway 💬
 [4] FLT4, KDR, PDGFRB, RET 💬 D08524 💬 Sorafenib [2] 34, 86 💬
99 Calcium signaling pathway 💬
 [1] HRH1 💬 D00300 💬 Diphenhydramine [8] 11, 13, 49, 51, 70, 86, 222, 256 💬
100 Calcium signaling pathway 💬
 [1] HRH2 💬 D00318 💬 Famotidine [6]  6 , 46, 61, 86, 98, 107 💬
101 Calcium signaling pathway 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
102 Calcium signaling pathway 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
103 cAMP signaling pathway 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
104 cAMP signaling pathway 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
105 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
106 cAMP signaling pathway 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
107 cAMP signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
108 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
109 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
110 cAMP signaling pathway 💬
 [1] DRD2 💬 D08132 💬 Lisuride [2]  6 , 86 💬
111 cAMP signaling pathway 💬
 [1] DRD2 💬 D01348 💬 Terguride [2] 51, 86 💬
112 cAMP signaling pathway 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
113 cAMP signaling pathway 💬
 [1] EDNRA 💬 D01227 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
114 cAMP signaling pathway 💬
 [1] EDNRA 💬 D07538 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
115 cAMP signaling pathway 💬
 [1] EDNRA 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
116 cAMP signaling pathway 💬
 [1] EDNRA 💬 D07171 💬 Sitaxentan [1] 86 💬
117 Carbohydrate digestion and absorption 💬
 [1] CACNA1D 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
118 Carbohydrate digestion and absorption 💬
 [1] CACNA1D 💬 D08270 💬 Nicardipine [2] 70, 86 💬
119 Carbohydrate digestion and absorption 💬
 [2] TAS1R2, TAS1R3 💬 D02381 💬 Aspartame [4]  6 , 13, 67, 86 💬
120 Cardiac muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
121 Cardiac muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
122 Cell cycle 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
123 Cell cycle 💬
 [1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
124 Cellular senescence 💬
 [1] CACNA1D 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
125 Cellular senescence 💬
 [1] CACNA1D 💬 D08270 💬 Nicardipine [2] 70, 86 💬
126 Cellular senescence 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
127 Cellular senescence 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
128 Central carbon metabolism in cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
129 Central carbon metabolism in cancer 💬
 [5] FLT3, KIT, PDGFRB, RAF1, RET 💬 D08524 💬 Sorafenib [2] 34, 86 💬
130 Central carbon metabolism in cancer 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
131 Central carbon metabolism in cancer 💬
 [3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
132 Central carbon metabolism in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
133 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
134 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
135 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
136 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
137 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
138 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
139 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
140 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
141 cGMP-PKG signaling pathway 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
142 cGMP-PKG signaling pathway 💬
 [1] EDNRA 💬 D07171 💬 Sitaxentan [1] 86 💬
143 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
144 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
145 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
146 cGMP-PKG signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
147 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
148 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
149 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D10027 💬 Udenafil [2] 86, 210 💬
150 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D08668 💬 Vardenafil [3] 13, 86, 299 💬
151 cGMP-PKG signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
152 Chagas disease 💬
 [1] ACE 💬 D00251 💬 Captopril [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
153 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
154 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
155 Chemical carcinogenesis - reactive oxygen species 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
156 Chemical carcinogenesis - reactive oxygen species 💬
 [1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
157 Chemical carcinogenesis - reactive oxygen species 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
158 Chemical carcinogenesis - reactive oxygen species 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
159 Chemical carcinogenesis - reactive oxygen species 💬
 [1] KEAP1 💬 D03846 💬 Dimethyl fumarate [5] 13, 49, 51, 86, 296 💬
160 Chemical carcinogenesis - reactive oxygen species 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
161 Chemical carcinogenesis - reactive oxygen species 💬
 [1] NQO1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
162 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
163 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
164 Chemical carcinogenesis - receptor activation 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
165 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
166 Chemical carcinogenesis - receptor activation 💬
 [3] AR, ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
167 Chemical carcinogenesis - receptor activation 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
168 Chemical carcinogenesis - receptor activation 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
169 Chemical carcinogenesis - receptor activation 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
170 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
171 Chemical carcinogenesis - receptor activation 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
172 Chemical carcinogenesis - receptor activation 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
173 Chemokine signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
174 Choline metabolism in cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
175 Choline metabolism in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
176 Choline metabolism in cancer 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
177 Choline metabolism in cancer 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
178 Choline metabolism in cancer 💬
 [2] PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
179 Cholinergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
180 Cholinergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
181 Chronic myeloid leukemia 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
182 Chronic myeloid leukemia 💬
 [1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
183 Chronic myeloid leukemia 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
184 Circadian entrainment 💬
 [2] CACNA1C, CACNA1D 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
185 Circadian entrainment 💬
 [2] CACNA1C, CACNA1D 💬 D08270 💬 Nicardipine [2] 70, 86 💬
186 Circadian entrainment 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
187 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
188 Cocaine addiction 💬
 [1] DRD2 💬 D08132 💬 Lisuride [2]  6 , 86 💬
189 Cocaine addiction 💬
 [1] DRD2 💬 D01348 💬 Terguride [2] 51, 86 💬
190 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D07917 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
191 Collecting duct acid secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
192 Colorectal cancer 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
193 Colorectal cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
194 Colorectal cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
195 Coronavirus disease - COVID-19 💬
 [1] ACE 💬 D00251 💬 Captopril [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
196 Coronavirus disease - COVID-19 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
197 Coronavirus disease - COVID-19 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
198 Coronavirus disease - COVID-19 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
199 Coronavirus disease - COVID-19 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
200 Coronavirus disease - COVID-19 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
201 Cortisol synthesis and secretion 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
202 Cortisol synthesis and secretion 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
203 Cortisol synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
204 Cortisol synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
205 Cushing syndrome 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
206 Cushing syndrome 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
207 Cushing syndrome 💬
 [1] BRAF 💬 D08524 💬 Sorafenib [2] 34, 86 💬
208 Cushing syndrome 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
209 Cushing syndrome 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
210 Cushing syndrome 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
211 Cytokine-cytokine receptor interaction 💬
 [1] ACVR2A 💬 D09670 💬 Sotatercept [2] 86, 284 💬
212 Cytokine-cytokine receptor interaction 💬
 [2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
213 Cytokine-cytokine receptor interaction 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
214 Cytokine-cytokine receptor interaction 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
215 Cytokine-cytokine receptor interaction 💬
 [1] PRL 💬 D01348 💬 Terguride [2] 51, 86 💬
216 Diabetic cardiomyopathy 💬
 [1] ACE 💬 D00251 💬 Captopril [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
217 Diabetic cardiomyopathy 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
218 Diabetic cardiomyopathy 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
219 Diabetic cardiomyopathy 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
220 Diabetic cardiomyopathy 💬
 [1] PARP1 💬 D09730 💬 Olaparib [2] 86, 285 💬
221 Diabetic cardiomyopathy 💬
 [3] PDK2, PDK3, PDK4 💬 D05857 💬 Sodium dichloroacetate [1] 86 💬
222 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
223 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
224 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
225 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
226 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
227 Dopaminergic synapse 💬
 [2] CACNA1C, CACNA1D 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
228 Dopaminergic synapse 💬
 [2] CACNA1C, CACNA1D 💬 D08270 💬 Nicardipine [2] 70, 86 💬
229 Dopaminergic synapse 💬
 [1] DRD2 💬 D01348 💬 Terguride [2] 51, 86 💬
230 Dopaminergic synapse 💬
 [3] DRD2, DRD3, DRD4 💬 D08132 💬 Lisuride [2]  6 , 86 💬
231 Dopaminergic synapse 💬
 [1] SCN1A 💬 D00358 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
232 Dopaminergic synapse 💬
 [1] SCN1A 💬 D08127 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
233 Drug metabolism - other enzymes 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
234 EGFR tyrosine kinase inhibitor resistance 💬
 [4] BRAF, KDR, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
235 EGFR tyrosine kinase inhibitor resistance 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
236 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
237 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
238 EGFR tyrosine kinase inhibitor resistance 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
239 EGFR tyrosine kinase inhibitor resistance 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
240 EGFR tyrosine kinase inhibitor resistance 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
241 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
242 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
243 Endocrine resistance 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
244 Endocrine resistance 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
245 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
246 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
247 Endocrine resistance 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
248 Endocytosis 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
249 Endocytosis 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
250 Endocytosis 💬
 [1] PDGFRA 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
251 Endometrial cancer 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
252 Endometrial cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
253 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
254 ErbB signaling pathway 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
255 ErbB signaling pathway 💬
 [1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
256 ErbB signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
257 ErbB signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
258 ErbB signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
259 Estrogen signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
260 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
261 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
262 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08233 💬 Morphine [5] 36, 46, 70, 85, 86 💬
263 Estrogen signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
264 Fc epsilon RI signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
265 Fc gamma R-mediated phagocytosis 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
266 Fluid shear stress and atherosclerosis 💬
 [1] ACVR2A 💬 D09670 💬 Sotatercept [2] 86, 284 💬
267 Fluid shear stress and atherosclerosis 💬
 [2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
268 Fluid shear stress and atherosclerosis 💬
 [1] KDR 💬 D08524 💬 Sorafenib [2] 34, 86 💬
269 Fluid shear stress and atherosclerosis 💬
 [1] KEAP1 💬 D03846 💬 Dimethyl fumarate [5] 13, 49, 51, 86, 296 💬
270 Fluid shear stress and atherosclerosis 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
271 Fluid shear stress and atherosclerosis 💬
 [1] NQO1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
272 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
273 Focal adhesion 💬
 [5] BRAF, FLT4, KDR, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
274 Focal adhesion 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
275 Focal adhesion 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
276 Focal adhesion 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
277 FoxO signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
278 FoxO signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
279 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
280 GABAergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
281 GABAergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
282 Gap junction 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
283 Gap junction 💬
 [1] ADRB1 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
284 Gap junction 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
285 Gap junction 💬
 [1] DRD2 💬 D08132 💬 Lisuride [2]  6 , 86 💬
286 Gap junction 💬
 [1] DRD2 💬 D01348 💬 Terguride [2] 51, 86 💬
287 Gap junction 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
288 Gap junction 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
289 Gap junction 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
290 Gap junction 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
291 Gap junction 💬
 [2] PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
292 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D07917 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
293 Gastric acid secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
294 Gastric acid secretion 💬
 [1] HRH2 💬 D00318 💬 Famotidine [6]  6 , 46, 61, 86, 98, 107 💬
295 Gastric cancer 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
296 Gastric cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
297 Gastric cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
298 Glioma 💬
 [3] BRAF, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
299 Glioma 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
300 Glioma 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
301 Glioma 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
302 Glioma 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
303 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
304 Glutamatergic synapse 💬
 [2] CACNA1C, CACNA1D 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
305 Glutamatergic synapse 💬
 [2] CACNA1C, CACNA1D 💬 D08270 💬 Nicardipine [2] 70, 86 💬
306 Glutathione metabolism 💬
 [1] ANPEP 💬 D00087 💬 Ubenimex [1] 86 💬
307 Glutathione metabolism 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
308 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
309 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
310 GnRH secretion 💬
 [1] ESR2 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
311 GnRH secretion 💬
 [1] ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
312 GnRH secretion 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
313 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
314 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
315 GnRH signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
316 GnRH signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
317 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
318 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
319 Growth hormone synthesis, secretion and action 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
320 Growth hormone synthesis, secretion and action 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
321 Hematopoietic cell lineage 💬
 [1] ANPEP 💬 D00087 💬 Ubenimex [1] 86 💬
322 Hematopoietic cell lineage 💬
 [2] FLT3, KIT 💬 D08524 💬 Sorafenib [2] 34, 86 💬
323 Hematopoietic cell lineage 💬
 [2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
324 Hematopoietic cell lineage 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
325 Hematopoietic cell lineage 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
326 Hematopoietic cell lineage 💬
 [1] KIT 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
327 Hematopoietic cell lineage 💬
 [1] KIT 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
328 Hematopoietic cell lineage 💬
 [1] MS4A1 💬 D02994 💬 Rituximab [48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
329 Hepatitis B 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
330 Hepatitis C 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
331 Hepatitis C 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
332 Hepatocellular carcinoma 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
333 Hepatocellular carcinoma 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
334 Hepatocellular carcinoma 💬
 [1] KEAP1 💬 D03846 💬 Dimethyl fumarate [5] 13, 49, 51, 86, 296 💬
335 Hepatocellular carcinoma 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
336 Hepatocellular carcinoma 💬
 [1] NQO1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
337 Herpes simplex virus 1 infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
338 HIF-1 signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
339 HIF-1 signaling pathway 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
340 HIF-1 signaling pathway 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
341 HIF-1 signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
342 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
343 Human cytomegalovirus infection 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
344 Human cytomegalovirus infection 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
345 Human cytomegalovirus infection 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
346 Human cytomegalovirus infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
347 Human cytomegalovirus infection 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
348 Human cytomegalovirus infection 💬
 [1] PDGFRA 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
349 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
350 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
351 Human cytomegalovirus infection 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
352 Human immunodeficiency virus 1 infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
353 Human immunodeficiency virus 1 infection 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
354 Human papillomavirus infection 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
355 Human papillomavirus infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
356 Human papillomavirus infection 💬
 [1] PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
357 Human papillomavirus infection 💬
 [2] PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
358 Human papillomavirus infection 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
359 Human papillomavirus infection 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
360 Human T-cell leukemia virus 1 infection 💬
 [2] IL1R1, IL1R2 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
361 Huntington disease 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
362 Huntington disease 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
363 Huntington disease 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
364 Hypertrophic cardiomyopathy 💬
 [1] ACE 💬 D00251 💬 Captopril [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
365 Hypertrophic cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
366 Hypertrophic cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
367 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
368 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
369 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
370 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 D00300 💬 Diphenhydramine [8] 11, 13, 49, 51, 70, 86, 222, 256 💬
371 Inflammatory mediator regulation of TRP channels 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
372 Inflammatory mediator regulation of TRP channels 💬
 [1] TRPV1 💬 D00250 💬 Capsaicin [3]  6 , 86, 226 💬
373 Influenza A 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
374 Insulin resistance 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
375 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
376 Insulin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
377 Insulin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
378 Insulin signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
379 Insulin signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
380 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
381 JAK-STAT signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
382 JAK-STAT signaling pathway 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
383 JAK-STAT signaling pathway 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
384 JAK-STAT signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
385 JAK-STAT signaling pathway 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
386 JAK-STAT signaling pathway 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
387 JAK-STAT signaling pathway 💬
 [2] PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
388 JAK-STAT signaling pathway 💬
 [1] PRL 💬 D01348 💬 Terguride [2] 51, 86 💬
389 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
390 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
391 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
392 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
393 Leishmaniasis 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
394 Leishmaniasis 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
395 Lipid and atherosclerosis 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
396 Lipid and atherosclerosis 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
397 Long-term depression 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
398 Long-term depression 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
399 Long-term potentiation 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
400 Long-term potentiation 💬
 [1] CACNA1C 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
401 Long-term potentiation 💬
 [1] CACNA1C 💬 D08270 💬 Nicardipine [2] 70, 86 💬
402 Longevity regulating pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
403 Longevity regulating pathway 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
404 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
405 Longevity regulating pathway - multiple species 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
406 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
407 MAPK signaling pathway 💬
 [7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
408 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
409 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
410 MAPK signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
411 MAPK signaling pathway 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
412 MAPK signaling pathway 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
413 MAPK signaling pathway 💬
 [3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
414 MAPK signaling pathway 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
415 Melanogenesis 💬
 [1] EDNRB 💬 D01227 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
416 Melanogenesis 💬
 [1] EDNRB 💬 D07538 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
417 Melanogenesis 💬
 [1] EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
418 Melanogenesis 💬
 [1] KIT 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
419 Melanogenesis 💬
 [1] KIT 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
420 Melanogenesis 💬
 [2] KIT, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
421 Melanoma 💬
 [3] BRAF, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
422 Melanoma 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
423 Melanoma 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
424 Melanoma 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
425 Metabolic pathways 💬
 [1] ANPEP 💬 D00087 💬 Ubenimex [1] 86 💬
426 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D07917 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
427 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
428 Metabolic pathways 💬
 [1] CYP19A1 💬 D00960 💬 Anastrozole [3] 78, 86, 193 💬
429 Metabolic pathways 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
430 Metabolic pathways 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
431 Metabolic pathways 💬
 [2] NQO1, VKORC1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
432 Metabolic pathways 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
433 Metabolic pathways 💬
 [1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
434 Metabolic pathways 💬
 [1] PDE5A 💬 D10027 💬 Udenafil [2] 86, 210 💬
435 Metabolic pathways 💬
 [1] PDE5A 💬 D08668 💬 Vardenafil [3] 13, 86, 299 💬
436 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
437 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
438 Metabolic pathways 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
439 MicroRNAs in cancer 💬
 [2] ABL1, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
440 MicroRNAs in cancer 💬
 [3] ABL1, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
441 MicroRNAs in cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
442 MicroRNAs in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
443 MicroRNAs in cancer 💬
 [2] PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
444 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
445 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
446 Morphine addiction 💬
 [1] OPRM1 💬 D08233 💬 Morphine [5] 36, 46, 70, 85, 86 💬
447 mTOR signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
448 mTOR signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
449 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
450 Natural killer cell mediated cytotoxicity 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
451 Necroptosis 💬
 [1] PARP1 💬 D09730 💬 Olaparib [2] 86, 285 💬
452 Neuroactive ligand-receptor interaction 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
453 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
454 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
455 Neuroactive ligand-receptor interaction 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
456 Neuroactive ligand-receptor interaction 💬
 [2] AGTR1, AGTR2 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
457 Neuroactive ligand-receptor interaction 💬
 [2] AGTR1, AGTR2 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
458 Neuroactive ligand-receptor interaction 💬
 [2] AVPR1A, AVPR2 💬 D07748 💬 Conivaptan [1] 86 💬
459 Neuroactive ligand-receptor interaction 💬
 [1] AVPR2 💬 D01213 💬 Tolvaptan [4] 67, 72, 86, 225 💬
460 Neuroactive ligand-receptor interaction 💬
 [3] DRD2, DRD3, DRD4 💬 D08132 💬 Lisuride [2]  6 , 86 💬
461 Neuroactive ligand-receptor interaction 💬
 [2] DRD2, PRL 💬 D01348 💬 Terguride [2] 51, 86 💬
462 Neuroactive ligand-receptor interaction 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
463 Neuroactive ligand-receptor interaction 💬
 [1] EDNRA 💬 D07171 💬 Sitaxentan [1] 86 💬
464 Neuroactive ligand-receptor interaction 💬
 [2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
465 Neuroactive ligand-receptor interaction 💬
 [2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
466 Neuroactive ligand-receptor interaction 💬
 [2] EDNRA, EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
467 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 D00300 💬 Diphenhydramine [8] 11, 13, 49, 51, 70, 86, 222, 256 💬
468 Neuroactive ligand-receptor interaction 💬
 [1] HRH2 💬 D00318 💬 Famotidine [6]  6 , 46, 61, 86, 98, 107 💬
469 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00407 💬 Methylprednisolone [46]  2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
470 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00473 💬 Prednisone [45]  2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
471 Neuroactive ligand-receptor interaction 💬
 [1] OPRM1 💬 D08233 💬 Morphine [5] 36, 46, 70, 85, 86 💬
472 Neuroactive ligand-receptor interaction 💬
 [1] PTGIR 💬 D02720 💬 Beraprost [1] 86 💬
473 Neuroactive ligand-receptor interaction 💬
 [1] PTGIR 💬 D00106 💬 Epoprostenol [1] 86 💬
474 Neuroactive ligand-receptor interaction 💬
 [1] PTGIR 💬 D02721 💬 Iloprost [4] 51, 84, 85, 86 💬
475 Neuroactive ligand-receptor interaction 💬
 [1] PTGIR 💬 D10725 💬 Ralinepag [1] 86 💬
476 Neuroactive ligand-receptor interaction 💬
 [1] PTGIR 💬 D09994 💬 Selexipag [5] 51, 70, 84, 86, 88 💬
477 Neuroactive ligand-receptor interaction 💬
 [1] PTGIR 💬 D06213 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
478 Neuroactive ligand-receptor interaction 💬
 [1] TRPV1 💬 D00250 💬 Capsaicin [3]  6 , 86, 226 💬
479 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
480 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
481 Neurotrophin signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
482 Neurotrophin signaling pathway 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
483 Neutrophil extracellular trap formation 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
484 Neutrophil extracellular trap formation 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
485 NF-kappa B signaling pathway 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
486 NF-kappa B signaling pathway 💬
 [1] PARP1 💬 D09730 💬 Olaparib [2] 86, 285 💬
487 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
488 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
489 Nitrogen metabolism 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
490 Non-alcoholic fatty liver disease 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
491 Non-alcoholic fatty liver disease 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
492 Non-alcoholic fatty liver disease 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
493 Non-alcoholic fatty liver disease 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
494 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
495 Non-small cell lung cancer 💬
 [3] BRAF, RAF1, RET 💬 D08524 💬 Sorafenib [2] 34, 86 💬
496 Non-small cell lung cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
497 Nucleotide metabolism 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
498 Oocyte meiosis 💬
 [1] AR 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
499 Osteoclast differentiation 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
500 Osteoclast differentiation 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
501 Ovarian steroidogenesis 💬
 [1] CYP19A1 💬 D00960 💬 Anastrozole [3] 78, 86, 193 💬
502 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
503 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
504 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D07917 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
505 Oxytocin signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
506 Oxytocin signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
507 Oxytocin signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
508 Oxytocin signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
509 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
510 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
511 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
512 Oxytocin signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
513 p53 signaling pathway 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
514 Pancreatic cancer 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
515 Pancreatic cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
516 Pancreatic cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
517 Pancreatic secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
518 Pancreatic secretion 💬
 [1] SLC12A2 💬 D00331 💬 Furosemide [2]  6 , 86 💬
519 Parathyroid hormone synthesis, secretion and action 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
520 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
521 Parkinson disease 💬
 [1] DRD2 💬 D08132 💬 Lisuride [2]  6 , 86 💬
522 Parkinson disease 💬
 [1] DRD2 💬 D01348 💬 Terguride [2] 51, 86 💬
523 Parkinson disease 💬
 [1] KEAP1 💬 D03846 💬 Dimethyl fumarate [5] 13, 49, 51, 86, 296 💬
524 Parkinson disease 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
525 Pathogenic Escherichia coli infection 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
526 Pathogenic Escherichia coli infection 💬
 [1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
527 Pathogenic Escherichia coli infection 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
528 Pathways in cancer 💬
 [3] ABL1, KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
529 Pathways in cancer 💬
 [4] ABL1, KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
530 Pathways in cancer 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
531 Pathways in cancer 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
532 Pathways in cancer 💬
 [3] AR, ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
533 Pathways in cancer 💬
 [7] BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬 D08524 💬 Sorafenib [2] 34, 86 💬
534 Pathways in cancer 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
535 Pathways in cancer 💬
 [1] EDNRA 💬 D07171 💬 Sitaxentan [1] 86 💬
536 Pathways in cancer 💬
 [2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
537 Pathways in cancer 💬
 [2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
538 Pathways in cancer 💬
 [2] EDNRA, EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
539 Pathways in cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
540 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
541 Pathways in cancer 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
542 Pathways in cancer 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
543 Pathways in cancer 💬
 [1] KEAP1 💬 D03846 💬 Dimethyl fumarate [5] 13, 49, 51, 86, 296 💬
544 Pathways in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
545 Pathways in cancer 💬
 [1] NQO1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
546 Pathways in cancer 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
547 Pathways in cancer 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
548 Pathways in cancer 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
549 Pathways of neurodegeneration - multiple diseases 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
550 Pathways of neurodegeneration - multiple diseases 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
551 Pathways of neurodegeneration - multiple diseases 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
552 Pathways of neurodegeneration - multiple diseases 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
553 Pathways of neurodegeneration - multiple diseases 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
554 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
555 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
556 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
557 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
558 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
559 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
560 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
561 Phospholipase D signaling pathway 💬
 [2] AVPR1A, AVPR2 💬 D07748 💬 Conivaptan [1] 86 💬
562 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 D01213 💬 Tolvaptan [4] 67, 72, 86, 225 💬
563 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
564 Phospholipase D signaling pathway 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
565 Phospholipase D signaling pathway 💬
 [3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
566 Phospholipase D signaling pathway 💬
 [3] KIT, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
567 Phospholipase D signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
568 PI3K-Akt signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
569 PI3K-Akt signaling pathway 💬
 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
570 PI3K-Akt signaling pathway 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
571 PI3K-Akt signaling pathway 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
572 PI3K-Akt signaling pathway 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
573 PI3K-Akt signaling pathway 💬
 [3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
574 PI3K-Akt signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
575 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
576 PI3K-Akt signaling pathway 💬
 [1] PRL 💬 D01348 💬 Terguride [2] 51, 86 💬
577 Platelet activation 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
578 Platelet activation 💬
 [1] P2RY12 💬 D07729 💬 Clopidogrel [3] 49, 51, 86 💬
579 Platelet activation 💬
 [1] P2RY12 💬 D10823 💬 Clopidogrel [3] 49, 51, 86 💬
580 Platelet activation 💬
 [1] P2RY12 💬 D10824 💬 Clopidogrel [3] 49, 51, 86 💬
581 Platelet activation 💬
 [1] PTGIR 💬 D02720 💬 Beraprost [1] 86 💬
582 Platelet activation 💬
 [1] PTGIR 💬 D00106 💬 Epoprostenol [1] 86 💬
583 Platelet activation 💬
 [1] PTGIR 💬 D02721 💬 Iloprost [4] 51, 84, 85, 86 💬
584 Platelet activation 💬
 [1] PTGIR 💬 D10725 💬 Ralinepag [1] 86 💬
585 Platelet activation 💬
 [1] PTGIR 💬 D09994 💬 Selexipag [5] 51, 70, 84, 86, 88 💬
586 Platelet activation 💬
 [1] PTGIR 💬 D06213 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
587 Platelet activation 💬
 [1] PTGS1 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
588 Platelet activation 💬
 [1] PTGS1 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
589 Platinum drug resistance 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
590 PPAR signaling pathway 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
591 Prion disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
592 Prion disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
593 Progesterone-mediated oocyte maturation 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
594 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
595 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
596 Prolactin signaling pathway 💬
 [1] PRL 💬 D01348 💬 Terguride [2] 51, 86 💬
597 Prolactin signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
598 Prostate cancer 💬
 [1] AR 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
599 Prostate cancer 💬
 [3] BRAF, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
600 Prostate cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
601 Prostate cancer 💬
 [1] IL1R2 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
602 Prostate cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
603 Prostate cancer 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
604 Prostate cancer 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
605 Protein processing in endoplasmic reticulum 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
606 Proteoglycans in cancer 💬
 [3] BRAF, KDR, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
607 Proteoglycans in cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
608 Proteoglycans in cancer 💬
 [1] ESR1 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
609 Proteoglycans in cancer 💬
 [1] ESR1 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
610 Proteoglycans in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
611 Proximal tubule bicarbonate reclamation 💬
 [2] CA2, CA4 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
612 Purine metabolism 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
613 Purine metabolism 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
614 Purine metabolism 💬
 [1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
615 Purine metabolism 💬
 [1] PDE5A 💬 D10027 💬 Udenafil [2] 86, 210 💬
616 Purine metabolism 💬
 [1] PDE5A 💬 D08668 💬 Vardenafil [3] 13, 86, 299 💬
617 Purine metabolism 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
618 Pyrimidine metabolism 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
619 Rap1 signaling pathway 💬
 [6] BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
620 Rap1 signaling pathway 💬
 [1] DRD2 💬 D08132 💬 Lisuride [2]  6 , 86 💬
621 Rap1 signaling pathway 💬
 [1] DRD2 💬 D01348 💬 Terguride [2] 51, 86 💬
622 Rap1 signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
623 Rap1 signaling pathway 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
624 Rap1 signaling pathway 💬
 [3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
625 Ras signaling pathway 💬
 [3] ABL1, KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
626 Ras signaling pathway 💬
 [4] ABL1, KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
627 Ras signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
628 Ras signaling pathway 💬
 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
629 Regulation of actin cytoskeleton 💬
 [3] BRAF, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
630 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
631 Regulation of actin cytoskeleton 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
632 Regulation of actin cytoskeleton 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
633 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
634 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
635 Regulation of lipolysis in adipocytes 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
636 Regulation of lipolysis in adipocytes 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
637 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
638 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
639 Relaxin signaling pathway 💬
 [1] EDNRB 💬 D01227 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
640 Relaxin signaling pathway 💬
 [1] EDNRB 💬 D07538 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
641 Relaxin signaling pathway 💬
 [1] EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
642 Relaxin signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
643 Relaxin signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
644 Renal cell carcinoma 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
645 Renin secretion 💬
 [1] ACE 💬 D00251 💬 Captopril [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
646 Renin secretion 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
647 Renin secretion 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
648 Renin secretion 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
649 Renin secretion 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
650 Renin secretion 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
651 Renin secretion 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
652 Renin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
653 Renin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
654 Renin secretion 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
655 Renin secretion 💬
 [1] EDNRA 💬 D01227 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
656 Renin secretion 💬
 [1] EDNRA 💬 D07538 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
657 Renin secretion 💬
 [1] EDNRA 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
658 Renin secretion 💬
 [1] EDNRA 💬 D07171 💬 Sitaxentan [1] 86 💬
659 Renin secretion 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
660 Renin-angiotensin system 💬
 [1] ACE 💬 D00251 💬 Captopril [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
661 Renin-angiotensin system 💬
 [2] AGTR1, AGTR2 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
662 Renin-angiotensin system 💬
 [2] AGTR1, AGTR2 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
663 Renin-angiotensin system 💬
 [1] ANPEP 💬 D00087 💬 Ubenimex [1] 86 💬
664 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
665 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
666 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
667 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
668 Salivary secretion 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
669 Salivary secretion 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
670 Salivary secretion 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
671 Salivary secretion 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
672 Salivary secretion 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
673 Salivary secretion 💬
 [1] SLC12A2 💬 D00331 💬 Furosemide [2]  6 , 86 💬
674 Salmonella infection 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
675 Serotonergic synapse 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
676 Serotonergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
677 Serotonergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
678 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
679 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
680 Serotonergic synapse 💬
 [1] SLC6A4 💬 D00326 💬 Fluoxetine [6] 13, 17, 78, 86, 179, 206 💬
681 Shigellosis 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
682 Shigellosis 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
683 Shigellosis 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
684 Signaling pathways regulating pluripotency of stem cells 💬
 [1] ACVR2A 💬 D09670 💬 Sotatercept [2] 86, 284 💬
685 Signaling pathways regulating pluripotency of stem cells 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
686 Small cell lung cancer 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
687 Small cell lung cancer 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
688 Sphingolipid signaling pathway 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
689 Sphingolipid signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
690 Spinocerebellar ataxia 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
691 Spinocerebellar ataxia 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
692 Steroid hormone biosynthesis 💬
 [1] CYP19A1 💬 D00960 💬 Anastrozole [3] 78, 86, 193 💬
693 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 D00326 💬 Fluoxetine [6] 13, 17, 78, 86, 179, 206 💬
694 T cell receptor signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
695 Taste transduction 💬
 [1] CACNA1C 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
696 Taste transduction 💬
 [1] CACNA1C 💬 D08270 💬 Nicardipine [2] 70, 86 💬
697 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 D00358 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
698 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 D08127 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
699 Taste transduction 💬
 [2] TAS1R2, TAS1R3 💬 D02381 💬 Aspartame [4]  6 , 13, 67, 86 💬
700 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
701 TGF-beta signaling pathway 💬
 [1] ACVR2A 💬 D09670 💬 Sotatercept [2] 86, 284 💬
702 Th17 cell differentiation 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
703 Th17 cell differentiation 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
704 Th17 cell differentiation 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
705 Th17 cell differentiation 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
706 Thermogenesis 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
707 Thermogenesis 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
708 Thermogenesis 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
709 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
710 Thyroid cancer 💬
 [2] BRAF, RET 💬 D08524 💬 Sorafenib [2] 34, 86 💬
711 Thyroid cancer 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
712 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
713 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
714 Thyroid hormone signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
715 Thyroid hormone signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
716 Tight junction 💬
 [1] CACNA1D 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
717 Tight junction 💬
 [1] CACNA1D 💬 D08270 💬 Nicardipine [2] 70, 86 💬
718 Tight junction 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
719 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
720 TNF signaling pathway 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
721 TNF signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
722 TNF signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
723 Transcriptional misregulation in cancer 💬
 [1] FLT3 💬 D08524 💬 Sorafenib [2] 34, 86 💬
724 Transcriptional misregulation in cancer 💬
 [1] IL1R2 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
725 Transcriptional misregulation in cancer 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
726 Tuberculosis 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
727 Type II diabetes mellitus 💬
 [2] CACNA1C, CACNA1D 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
728 Type II diabetes mellitus 💬
 [2] CACNA1C, CACNA1D 💬 D08270 💬 Nicardipine [2] 70, 86 💬
729 Type II diabetes mellitus 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
730 Ubiquinone and other terpenoid-quinone biosynthesis 💬
 [2] NQO1, VKORC1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
731 Ubiquitin mediated proteolysis 💬
 [1] KEAP1 💬 D03846 💬 Dimethyl fumarate [5] 13, 49, 51, 86, 296 💬
732 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
733 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
734 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
735 Vascular smooth muscle contraction 💬
 [1] AVPR1A 💬 D07748 💬 Conivaptan [1] 86 💬
736 Vascular smooth muscle contraction 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
737 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
738 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
739 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
740 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 D01227 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
741 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 D07538 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
742 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
743 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 D07171 💬 Sitaxentan [1] 86 💬
744 Vascular smooth muscle contraction 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
745 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 D02720 💬 Beraprost [1] 86 💬
746 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 D00106 💬 Epoprostenol [1] 86 💬
747 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 D02721 💬 Iloprost [4] 51, 84, 85, 86 💬
748 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 D10725 💬 Ralinepag [1] 86 💬
749 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 D09994 💬 Selexipag [5] 51, 70, 84, 86, 88 💬
750 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 D06213 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
751 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 D07748 💬 Conivaptan [1] 86 💬
752 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 D01213 💬 Tolvaptan [4] 67, 72, 86, 225 💬
753 VEGF signaling pathway 💬
 [2] KDR, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
754 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
755 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
756 Vibrio cholerae infection 💬
 [1] SLC12A2 💬 D00331 💬 Furosemide [2]  6 , 86 💬
757 Viral myocarditis 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
758 Viral myocarditis 💬
 [1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
759 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [3] 11, 13, 86 💬
760 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬

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