DDrare: Database of Drug Development for Rare Diseases

Searched query = "Eosinophilic granulomatosis with Polyangiitis", "EGPA", "Eosinophilic multiple vasculitis granulomatous disease", "Allergic granulomatous angiitis", "Churg-Strauss syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = Anti-thymocyte globulin; Azathioprine; Benralizumab; CYCLOPHOSPHAMIDE; Corticosteroid; Corticosteroid and azathioprine; Cyclophosphamide; Cyclophosphamide, Azathioprine,prednisone,methylprednisolone; Cyclosporine; Filgrastim; Freeze-Dried Sulfonated Human Normal Immunoglobulin (GGS); HPC cell infusion; Human normal immunoglobulin; Hydroxychloroquine; Infliximab; L04AC06; MEDI-563; MEPOLIZUMAB; MESNA; Mepolizumab; Mesna; Methotrexate; Methylprednisolone; Mycophenolate; Mycophenolate mofetil; Mycophenolate mofetil,methotrexate; NUCALA; Naltrexone; Naltrexone Hydrochloride; Nucala; Nucala 100 mg powder for solution for injection; Placebo (physiological saline); Plaquenil - Hydroxychloroquine 200mg Film coated tablets; Prednisolone; Prednisone; Prednisone, methylprednisolone,cyclophosphamides; Procedure: Autologous Peripheral Blood Stem Cell Transplantation; RITUXIMAB; Rituximab; SB-240563; SB-240563 (mepolizumab)

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00647166 (ClinicalTrials.gov)	May 2008	26/3/2008	Association Corticosteroid/Azathioprine in Microscopic Polyangiitis/ Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome)	Evaluation of a New Treatment Strategy for Patients With Microscopic Polyangiitis, Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome) Without Poor Prognosis Factors	MPA;PAN or EGPA With FFS=0;At Diagnosis or Within the First 15 Days Following Initiation of Corticosteroids	Drug: corticosteroid and azathioprine;Drug: corticosteroid and placebo	Assistance Publique - Hôpitaux de Paris	NULL	Completed	18 Years	N/A	Both	114	Phase 3	France
2	NCT00307671 (ClinicalTrials.gov)	July 2005	27/3/2006	Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years	Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years Comparison of Two Strategies Combining Steroids With or Without Immunosuppressants	Vasculitis;Wegener's Granulomatosis;Microscopic Polyangiitis;Churg-Strauss Syndrome;Polyarteritis Nodosa	Drug: prednisone , methylprednisolone,cyclophosphamides;Drug: Cyclophosphamide , Azathioprine,prednisone,methylprednisolone;Drug: Mycophenolate mofetil ,methotrexate	Assistance Publique - Hôpitaux de Paris	NULL	Completed	65 Years	N/A	Both	108	Phase 4	France
3	NCT00399399 (ClinicalTrials.gov)	July 1996	13/11/2006	CHUSPAN SCS BP Treatment of Churg–Strauss Syndrome Without Poor-Prognosis Factors	CHUSPAN SCS BP Treatment of Churg–Strauss Syndrome Without Poor-Prognosis Factors: a Prospective Randomized Study in 72 Patients.	Churg-Strauss Syndrome	Drug: azathioprine;Drug: cyclophosphamide	Hospices Civils de Lyon	NULL	Active, not recruiting	15 Years	90 Years	Both	72	Phase 4	Switzerland

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT00647166
(ClinicalTrials.gov)

May 2008

26/3/2008

Association Corticosteroid/Azathioprine in Microscopic Polyangiitis/ Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome)

Evaluation of a New Treatment Strategy for Patients With Microscopic Polyangiitis, Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome) Without Poor Prognosis Factors

MPA;PAN or EGPA With FFS=0;At Diagnosis or Within the First 15 Days Following Initiation of Corticosteroids

Drug: corticosteroid and azathioprine;Drug: corticosteroid and placebo

Assistance Publique - Hôpitaux de Paris

NULL

Completed

18 Years

N/A

Both

114

Phase 3

France

NCT00307671
(ClinicalTrials.gov)

July 2005

27/3/2006

Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years

Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years Comparison of Two Strategies Combining Steroids With or Without Immunosuppressants

Vasculitis;Wegener's Granulomatosis;Microscopic Polyangiitis;Churg-Strauss Syndrome;Polyarteritis Nodosa

Drug: prednisone , methylprednisolone,cyclophosphamides;Drug: Cyclophosphamide , Azathioprine,prednisone,methylprednisolone;Drug: Mycophenolate mofetil ,methotrexate

Assistance Publique - Hôpitaux de Paris

NULL

Completed

65 Years

N/A

Both

108

Phase 4

France

NCT00399399
(ClinicalTrials.gov)

July 1996

13/11/2006

CHUSPAN SCS BP Treatment of Churg–Strauss Syndrome Without Poor-Prognosis Factors

CHUSPAN SCS BP Treatment of Churg–Strauss Syndrome Without Poor-Prognosis Factors: a Prospective Randomized Study in 72 Patients.

Churg-Strauss Syndrome

Drug: azathioprine;Drug: cyclophosphamide

Hospices Civils de Lyon

NULL

Active, not recruiting

15 Years

90 Years

Both

Phase 4

Switzerland