DDrare: Database of Drug Development for Rare Diseases

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Ascorbic acid (vitamin c) and alpha-tocopherol (vitamin e) (DrugBank: Ascorbic acid, Vitamin C, Vitamin E, alpha-tocopherol, Tocopherol)

8 diseases

ID	Disease name (Link within this page)	Number of trials
10	Charcot-Marie-Tooth disease	0
97	Ulcerative colitis	0
192	Cockayne syndrome	0
206	Fragile X syndrome	1
210	Single Ventricle	0
211	Hypoplastic left heart syndrome	0
212	Tricuspid atresia	0
298	Hereditary pancreatitis	0

10. Charcot-Marie-Tooth disease [ 31 clinical trials, 38 drugs, (DrugBank: 9 drugs), 11 drug target genes, 14 drug target pathways]

Searched query = "Charcot-Marie-Tooth disease", "CMT"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 31 trial found

97. Ulcerative colitis [ 2,269 clinical trials, 1,331 drugs, (DrugBank: 241 drugs), 114 drug target genes, 181 drug target pathways]

Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 2,269 trial found

192. Cockayne syndrome [ 4 clinical trials, 7 drugs, (DrugBank: 3 drugs), 1 drug target gene, 50 drug target pathways]

Searched query = "Cockayne syndrome", "CS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 4 trial found

206. Fragile X syndrome [ 98 clinical trials, 73 drugs, (DrugBank: 27 drugs), 46 drug target genes, 57 drug target pathways]

Searched query = "Fragile X syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 98 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01329770 (ClinicalTrials.gov)	December 2010	29/3/2011	Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome	Phase II Double-blind Randomized Placebo-controlled 1-way Crossover Trial to Investigate Safety and Efficacy of the Ascorbic Acid and Tocopherol for the Treatment of the Fragile X Syndrome	Fragile X Syndrome	Dietary Supplement: Ascorbic Acid (Vitamin C) and Alpha-tocopherol (Vitamin E);Dietary Supplement: Placebo	Yolanda de Diego Otero	NULL	Completed	6 Years	18 Years	Male	30	Phase 2	Spain

210. Single Ventricle [ 47 clinical trials, 54 drugs, (DrugBank: 23 drugs), 32 drug target genes, 66 drug target pathways]

Searched query = "Single Ventricle", "SV", "Single ventricle heart defect", "Univentricular heart", "UVH", "Single ventricular circulation syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 47 trial found

211. Hypoplastic left heart syndrome [ 20 clinical trials, 28 drugs, (DrugBank: 9 drugs), 5 drug target genes, 13 drug target pathways]

Searched query = "Hypoplastic left heart syndrome", "HLHS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 20 trial found

212. Tricuspid atresia [ 6 clinical trials, 8 drugs, (DrugBank: 7 drugs), 8 drug target genes, 12 drug target pathways]

Searched query = "Tricuspid atresia", "TA"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 6 trial found

298. Hereditary pancreatitis [ 93 clinical trials, 168 drugs, (DrugBank: 51 drugs), 48 drug target genes, 134 drug target pathways]

Searched query = "Hereditary pancreatitis", "Chronic pancreatitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 93 trial found