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Epi-743    (DrugBank: -)

2 diseases
IDDisease name (Link within this page)Number of trials
21Mitochondrial disease1
156Rett syndrome2

21. Mitochondrial disease    [ 23 clinical trials,   29 drugs,   (DrugBank: 28 drugs),   44 drug target genes,   65 drug target pathways]
Searched query = "Mitochondrial disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 23 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT01642056
(ClinicalTrials.gov)		September 1, 201214/7/2012EPI-743 for Metabolism or Mitochondrial DisordersTherapeutic Trial of EPI -743 In Patients With Disorders of Energy Utilization or Oxidation-ReductionMitochondrial Disease;Neurology;MyoptahyDrug: EPI-743;Drug: PlaceboNational Human Genome Research Institute (NHGRI)NULLCompleted2 Years11 YearsAll20Phase 1;Phase 2United States

156. Rett syndrome    [ 36 clinical trials,   49 drugs,   (DrugBank: 19 drugs),   77 drug target genes,   112 drug target pathways]
Searched query = "Rett syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 36 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1EUCTR2012-005021-76-IT
(EUCTR)		31/01/201311/12/2012Phase 2A clinical trial conducted on children affected by Rett syndrome and who are casually administered with the experimental treatment, EPI-743, compared versus the se of placebo.A Phase 2A Randomized, Placebo Controlled Trial of EPI-743 in Children with Rett Syndrome Rett Syndrome
MedDRA version: 14.1;Level: HLGT;Classification code 10021605;Term: Inborn errors of metabolism;System Organ Class: 10027433 - Metabolism and nutrition disorders;Therapeutic area: Diseases [C] - Nutritional and Metabolic Diseases [C18]		Product Name: EPI-743
Product Code: NA
Other descriptive name: Alpha-tocotrienol quinone		EDISON PHARMACEUTICALS INC.NULLNot RecruitingFemale: yes
Male: no		Phase 2AItaly
2NCT01822249
(ClinicalTrials.gov)		January 201325/3/2013Phase 2 Study of EPI-743 for Treatment of Rett SyndromeA Phase 2A Randomized, Placebo Controlled Trial of EPI-743 in Children With Rett SyndromeRett SyndromeDrug: EPI-743;Drug: PlaceboEdison Pharmaceuticals IncNULLCompletedN/A18 YearsFemale24Phase 2Italy