DDrare: Database of Drug Development for Rare Diseases

Rapamycin-calcitriol combination (DrugBank: Calcitriol, Rapamycin)

8 diseases

ID	Disease name (Link within this page)	Number of trials
37	Generalised pustular psoriasis	0
46	Malignant rheumatoid arthritis	0
49	Systemic lupus erythematosus	0
66	IgA nephropathy	0
96	Crohn disease	0
158	Tuberous sclerosis	1
235	Hypoparathyroidism	0
326	Osteopetrosis	0

37. Generalised pustular psoriasis [ 58 clinical trials, 50 drugs, (DrugBank: 18 drugs), 17 drug target genes, 96 drug target pathways]

Searched query = "Generalised pustular psoriasis", "Pustular psoriasis", "Herpetic impetigo", "Generalization of acrodermatitis continua", "Generalization of dermatitis continua of the extremities"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 58 trial found

46. Malignant rheumatoid arthritis [ 4,183 clinical trials, 2,538 drugs, (DrugBank: 401 drugs), 183 drug target genes, 219 drug target pathways]

Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 4,183 trial found

49. Systemic lupus erythematosus [ 827 clinical trials, 638 drugs, (DrugBank: 168 drugs), 108 drug target genes, 191 drug target pathways]

Searched query = "Systemic lupus erythematosus", "SLE"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 827 trial found

66. IgA nephropathy [ 199 clinical trials, 214 drugs, (DrugBank: 57 drugs), 32 drug target genes, 128 drug target pathways]

Searched query = "IgA nephropathy", "IgA nephritis", "Berger disease", "IgA-IgG nephropathy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 199 trial found

96. Crohn disease [ 2,209 clinical trials, 1,276 drugs, (DrugBank: 240 drugs), 166 drug target genes, 210 drug target pathways]

Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 2,209 trial found

158. Tuberous sclerosis [ 100 clinical trials, 62 drugs, (DrugBank: 16 drugs), 35 drug target genes, 115 drug target pathways]

Searched query = "Tuberous sclerosis", "Tuberous sclerosis complex"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 100 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03140449 (ClinicalTrials.gov)	September 5, 2013	26/4/2017	Topical Rapamycin and Calcitriol for Angiofibroma of Tuberous Sclerosis	Study of Combination Therapy With Topical Rapamycin and Calcitriol for Cutaneous Lesions of Tuberous Sclerosis: A Double-blind Randomized Controlled Trial	Facial Angiofibroma	Drug: Rapamycin;Drug: Calcitriol;Drug: Rapamycin-calcitriol combination	National Taiwan University Hospital	NULL	Completed	7 Years	65 Years	All	52	Phase 3	NULL

235. Hypoparathyroidism [ 67 clinical trials, 112 drugs, (DrugBank: 24 drugs), 4 drug target genes, 5 drug target pathways]

Searched query = "Hypoparathyroidism", "Accessory thyroid hypergasia disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 67 trial found

326. Osteopetrosis [ 20 clinical trials, 52 drugs, (DrugBank: 14 drugs), 16 drug target genes, 78 drug target pathways]

Searched query = "Osteopetrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 20 trial found