DDrare: Database of Drug Development for Rare Diseases

Mepolizumab (a-il-5 antibody) (DrugBank: Mepolizumab)

4 diseases

ID	Disease name (Link within this page)	Number of trials
44	Wegener granulomatosis	0
45	Eosinophilic granulomatosis with Polyangiitis	0
98	Eosinophilic gastrointestinal disease	0
162	Pemphigoid	1

44. Wegener granulomatosis [ 84 clinical trials, 88 drugs, (DrugBank: 22 drugs), 13 drug target genes, 37 drug target pathways]

Searched query = "Wegener granulomatosis", "Multiple vasculitis granulomatous disease", "Granulomatosis with polyangiitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 84 trial found

45. Eosinophilic granulomatosis with Polyangiitis [ 27 clinical trials, 41 drugs, (DrugBank: 18 drugs), 18 drug target genes, 98 drug target pathways]

Searched query = "Eosinophilic granulomatosis with Polyangiitis", "EGPA", "Eosinophilic multiple vasculitis granulomatous disease", "Allergic granulomatous angiitis", "Churg-Strauss syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 27 trial found

98. Eosinophilic gastrointestinal disease [ 128 clinical trials, 147 drugs, (DrugBank: 40 drugs), 34 drug target genes, 132 drug target pathways]

Searched query = "Eosinophilic gastrointestinal disease", "Eosinophilic gastroenteritis", "Eosinophilic esophagitis", "Eosinophilic colitis", "Eosinophilic gastro-intestinal disorder", "EGID", "Neonatal food-protein induced enterocolitis", "N-FPIES"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 128 trial found

162. Pemphigoid [ 70 clinical trials, 117 drugs, (DrugBank: 46 drugs), 30 drug target genes, 128 drug target pathways]

Searched query = "Pemphigoid", "Epidermolysis bullosa acquisita"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 70 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01705795 (ClinicalTrials.gov)	February 13, 2013	5/10/2012	Anti-IL-5 Therapy in Bullous Pemphigoid (BP)	Anti-IL-5 Therapy in Bullous Pemphigoid. Randomized, Placebo-controlled, Double-blind Study Evaluating the Effect of Anti-IL-5 Therapy in Patients With Bullous Pemphigoid.	Pemphigoid, Bullous	Drug: Mepolizumab (a-IL-5 antibody);Drug: Placebo	University Hospital Inselspital, Berne	NULL	Completed	18 Years	N/A	All	32	Phase 2	Switzerland