Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abacavir 4件: Abacavir; Abacavir sulfate; Triumeq; Ziagen2件: D00891 ,
D07057 		--4件: 2, 135, 265, 325
2 Acetate 1件: Acetate---43件: 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
3 Acetylcarnitine 2件: Acetyl-L-carnitine; Acetylcarnitine---3件: 2, 265, 298
4 Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins 1件: HB-adMSCs---7件: 2, 4, 6, 13, 46, 49, 113
5 Albumin human 5件: Albumin; Human albumin; Human serum albumin; Optison; Serum albumin2件: D02792 ,
D05424 		--3件: 2, 78, 96
6 Aldesleukin 4件: Aldesleukin; ILT-101; Proleukin; Recombinant human interleukin-21件: D00748 3件: IL2RA,
IL2RB,
IL2RG 💬		14件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬6件: 2, 35, 49, 65, 96, 97
7 Ampicillin 1件: ABPC3件: D00204 ,
D01251 ,
D02119 		--5件: 2, 6, 13, 84, 299
8 Anakinra 2件: Anakinra; Kineret1件: D02934 2件: IL1R1,
IL1R2 💬		15件: Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬19件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
9 Arimoclomol 1件: ARIMOCLOMOL1件: D11374 --3件: 2, 15, 19
10 Arundic acid 1件: Arundic Acid1件: D06296 --1件: 2
11 Atropine 2件: Atropina; Atropine5件: D00113 ,
D01077 ,
D02069 ,
D03011 ,
D03814 		5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 2, 299
12 Baclofen 2件: Baclofen; Kemstro1件: D00241 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬7件: 2, 10, 13, 18, 65, 149, 206
13 Barium 1件: Barium---3件: 2, 19, 98
14 Basiliximab 2件: Basiliximab; Simulect1件: D03058 1件: IL2RA 💬11件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬6件: 2, 50, 66, 97, 222, 228
15 Betamethasone 1件: Betamethasone7件: D00244 ,
D00972 ,
D01357 ,
D01402 ,
D01637 ,
D02032 ,
D02286 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬7件: 2, 28, 46, 83, 90, 96, 235
16 Biotin 4件: BIOTIN; Biotina; D-BIOTIN; Vitamin B71件: D00029 --5件: 2, 8, 10, 13, 20
17 Bosutinib 1件: BOSUTINIB1件: D03252 2件: ABL1,
SRC 💬		49件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬2件: 2, 67
18 Botulinum toxin type A 8件: BOTOX; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬13件: 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226
19 Botulinum toxin type B 3件: Botulinum toxin type B; NEUROBLOC; RimabotulinumtoxinB1件: D02735 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬4件: 2, 6, 13, 51
20 Butylphthalide 1件: Butylphthalide---4件: 2, 6, 18, 22
21 Caffeine 1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
22 Calusterone 0件: 1件: D03338 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬3件: 2, 46, 71
23 Cannabidiol 3件: CANNABIDIOL; Epidyolex; SATIVEX1件: D10915 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬19件: 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
24 Capsaicin 2件: Capsaicin; Qutenza1件: D00250 1件: TRPV1 💬2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬5件: 2, 6, 19, 86, 226
25 Carbidopa 7件: Carbidopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00558 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬9件: 2, 4, 6, 13, 17, 90, 140, 164, 201
26 Carbonate ion 1件: Carbonate---12件: 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299
27 Ceftriaxone 1件: Ceftriaxone2件: D00924 ,
D07659 		--3件: 2, 6, 97
28 Celecoxib 2件: CELEBREX; Celecoxib1件: D00567 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
29 Censavudine 1件: CENSAVUDINE1件: D10550 --2件: 2, 127
30 Cimetidine 1件: Cimetidine2件: D00295 ,
D03503 		1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 2, 254
31 Ciprofloxacin 2件: Ciprofloxacin; Ciprofloxacin hydrochloride2件: D00186 ,
D02216 		--5件: 2, 60, 96, 97, 299
32 Clenbuterol 1件: Clenbuterol1件: D07713 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 1, 2, 6, 13, 256
33 Colchicine 2件: COLCHICINA; Colchicine1件: D00570 9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬7件: 2, 42, 46, 56, 93, 210, 266
34 Copper 2件: Copper; Nicotinamide---4件: 2, 169, 170, 171
35 Corticotropin 5件: ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin1件: D00146 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬15件: 2, 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222
36 Creatine 1件: Creatine---16件: 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 113, 156, 201, 256
37 Creatinine 1件: Creatinine1件: D03600 --4件: 2, 46, 60, 70
38 Cromoglicic acid 4件: Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium2件: D00526 ,
D07753 		--3件: 2, 85, 98
39 Curcumin 1件: Curcumin---11件: 2, 13, 46, 49, 67, 74, 94, 96, 97, 139, 299
40 Darunavir 1件: Darunavir1件: D03656 --1件: 2
41 Deferiprone 2件: DEFERIPRONE; Ferriprox1件: D07416 --6件: 2, 6, 18, 120, 122, 233
42 Dexmedetomidine 4件: Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE2件: D00514 ,
D01205 		3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
43 Dexpramipexole 1件: Dexpramipexole1件: D09886 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 2
44 Dextran 1件: Dextran1件: D00060 --5件: 2, 62, 79, 96, 97
45 Dextromethorphan 4件: Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta3件: D00848 ,
D03742 ,
D03744 		6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
46 Dextrose, unspecified form 2件: Dextrose; Glucose---19件: 2, 6, 13, 49, 50, 56, 60, 65, 70, 75, 86, 88, 96, 160, 195, 226, 254, 257, 299
47 Dolutegravir 2件: Dolutegravir; Triumeq1件: D10066 --2件: 2, 265
48 Dronabinol 4件: Delta-9-tetrahydrocannabinol; DRONABINOL; SATIVEX; Tetrahydrocannabinol1件: D00306 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬8件: 2, 8, 13, 36, 46, 96, 271, 298
49 Dutasteride 2件: Dutasterida; Dutasteride1件: D03820 2件: SRD5A1,
SRD5A2 💬		3件: Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬2件: 1, 2
50 Edaravone 3件: EDARAVONE; Methylphenylpyrazolone; Norphenazone1件: D01552 --2件: 2, 22
51 Enoxacin 1件: Enoxacin2件: D00310 ,
D05461 		--1件: 2
52 Eperisone 1件: EPERISONE1件: D07898 --1件: 2
53 EPI-589 1件: EPI-589---2件: 2, 6
54 Erythropoietin 4件: EPOETIN ALFA; Epoetin beta; Erythropoietin; Neorecormon1件: D03231 1件: EPOR 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬10件: 2, 6, 13, 18, 22, 46, 47, 70, 95, 96
55 Escitalopram 3件: Citalopram; Escitalopram; Escitalopram oxalate3件: D02567 ,
D07704 ,
D07913 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬3件: 2, 6, 13
56 Esketamine 3件: Esketamine; KETAMINE; S-ketamine1件: D07283 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬3件: 2, 4, 70
57 Ezogabine 4件: Ezogabine; Potiga; RETIGABINE; Trobalt1件: D09569 5件: KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬		6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬2件: 2, 144
58 Fasudil 1件: Fasudil1件: D07941 2件: ROCK1,
ROCK2 💬		23件: Axon guidance, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 2, 5, 7, 51
59 Febuxostat 1件: Febuxostat1件: D01206 1件: XDH 💬5件: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Peroxisome, Purine metabolism 💬3件: 2, 6, 13
60 Fig 1件: Fig---1件: 2
61 Filgrastim 7件: Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio1件: D03235 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬34件: 2, 6, 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
62 Glatiramer 5件: COP-1; COPAXONE; Copolymer-1; Glatiramer; GLATIRAMER ACETATE1件: D04318 20件: HLA-A,
HLA-B,
HLA-C,
HLA-DMA,
HLA-DMB,
HLA-DOA,
HLA-DOB,
HLA-DPA1,
HLA-DPB1,
HLA-DQA1,
HLA-DQA2,
HLA-DQB1,
HLA-DRA,
HLA-DRB1,
HLA-DRB3,
HLA-DRB4,
HLA-DRB5,
HLA-E,
HLA-F,
HLA-G 💬		32件: Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cellular senescence, Endocytosis, Epstein-Barr virus infection, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Phagosome, Rheumatoid arthritis, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis 💬4件: 2, 13, 96, 156
63 Gold 1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318
64 Guanabenz 1件: GUANABENZ1件: D04375 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬2件: 2, 13
65 Human interleukin-2 3件: Human interleukin-2; IL-2; INTERLEUKIN-2---18件: 2, 13, 35, 46, 49, 51, 53, 55, 56, 60, 63, 65, 95, 96, 97, 107, 162, 271
66 Human Umbilical Cord Mesenchymal Stem Cells 4件: Human Umbilical Cord Mesenchymal Stem Cells; Mesenchymal Stromal Cells; UC-MSCs; WJ-MSCs---13件: 2, 13, 36, 46, 49, 51, 60, 96, 97, 107, 113, 274, 284
67 Ibudilast 1件: Ibudilast1件: D01385 8件: CYSLTR1,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PTGIR 💬		16件: Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 13
68 Inosine 1件: Inosine1件: D00054 --6件: 2, 6, 13, 17, 85, 122
69 Iodide I-123 2件: I 123; I-123---2件: 2, 6
70 Ioflupane I-123 3件: DaTSCAN; Ioflupane; Ioflupane I 123---4件: 2, 5, 6, 17
71 Ketamine 2件: Ketamine; NMDA2件: D00711 ,
D08098 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 4, 6, 13, 70, 113, 156, 215
72 Lacosamide 1件: Lacosamide1件: D07299 2件: SCN3A,
SCN9A 💬		1件: Taste transduction 💬3件: 2, 46, 149
73 Lactose 1件: Lactose2件: D00046 ,
D03226 		--6件: 2, 6, 13, 97, 228, 310
74 Lamivudine 4件: COMBIVIR; Epivir; Lamivudine; Triumeq1件: D00353 --7件: 2, 26, 42, 46, 135, 265, 325
75 Lenograstim 2件: G-CSF; Lenograstim1件: D03247 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬7件: 2, 13, 16, 18, 19, 57, 65
76 Leuprolide 2件: Leuprolide; Leuprorelin1件: D00989 1件: GNRHR 💬2件: GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬5件: 1, 2, 3, 51, 76
77 Levetiracetam 2件: KEPPRA; Levetiracetam1件: D00709 1件: SV2A 💬1件: ECM-receptor interaction 💬5件: 2, 4, 6, 13, 307
78 Levodopa 8件: DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00059 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬8件: 2, 4, 6, 17, 90, 140, 164, 201
79 Levosimendan 1件: LEVOSIMENDAN1件: D04720 2件: PDE3A,
PDE3B 💬		11件: Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 2
80 Linoleic acid 1件: Linoleic acid---8件: 2, 5, 6, 13, 75, 76, 222, 299
81 Lipoic acid 3件: Alpha Lipoic Acid; ALPHA-LIPOIC ACID; Lipoic acid2件: D00048 ,
D00086 		--5件: 2, 5, 13, 14, 20
82 Lithium carbonate 2件: Lithium; Lithium Carbonate1件: D00801 --6件: 2, 13, 17, 18, 19, 127
83 Lithium citrate 2件: Lithium; LITHIUM CITRATE1件: D04749 --5件: 2, 5, 6, 7, 8
84 Lunasine 1件: Lunasin---1件: 2
85 Masitinib 1件: Masitinib1件: D10229 1件: KIT 💬11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬6件: 2, 5, 6, 13, 46, 96
86 Mecobalamin 2件: Mecobalamin; Methylcobalamin1件: D03246 --2件: 2, 70
87 Medical Cannabis 3件: Cannabis; Marijuana; Medical Cannabis---9件: 2, 6, 13, 19, 46, 90, 96, 97, 271
88 Memantine 3件: Ebixa; Memantine; MEMANTINE HYDROCHLORIDE2件: D04905 ,
D08174 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬7件: 2, 6, 8, 13, 49, 127, 205
89 Metformin 5件: Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine2件: D00944 ,
D04966 		2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
90 Methamidophos 1件: MONITOR---20件: 2, 11, 13, 19, 28, 46, 49, 58, 65, 70, 81, 85, 86, 98, 113, 118, 129, 298, 299, 300
91 Methane 1件: Methane---1件: 2
92 Methylprednisolone 4件: Medrol; Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE6件: D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
93 Mexiletine 4件: Mexiletina; Mexiletine; Mexitil; Namuscla2件: D00639 ,
D08215 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬5件: 1, 2, 10, 113, 114
94 Midazolam 2件: Midazolam; Midazolam injection3件: D00550 ,
D00696 ,
D05028 		16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
95 Minocycline 3件: Minocycline; Minocycline hydrochloride; Minomycin2件: D00850 ,
D05045 		--14件: 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299
96 Moxifloxacin 2件: Moxifloxacin; Moxifloxacin hydrochloride2件: D00874 ,
D08237 		--9件: 2, 6, 46, 49, 85, 86, 113, 240, 299
97 Mycophenolate mofetil 3件: CELLCEPT; Mycophenolate mofetil; Mycophenolate mofetil TEVA3件: D00752 ,
D05094 ,
D05095 		2件: IMPDH1,
IMPDH2 💬		3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
98 Mycophenolic acid 5件: Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic1件: D05096 2件: IMPDH1,
IMPDH2 💬		3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
99 Nicotinamide 4件: Ginseng; Multivitamin; Niacinamide; Nicotinamide1件: D00036 --11件: 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
100 Nicotinamide riboside 1件: Nicotinamide Riboside---4件: 2, 6, 18, 191
101 Olanzapine 2件: Olanzapine; Zyprexa2件: D00454 ,
D06623 		11件: ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 8
102 Ozanezumab 1件: Ozanezumab1件: D10331 1件: RTN4 💬1件: Alzheimer disease 💬1件: 2
103 Palmidrol 1件: Palmitoylethanolamide1件: D08328 --1件: 2
104 Pegcetacoplan 1件: PEGCETACOPLAN1件: D11613 1件: C3 💬17件: Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬3件: 2, 62, 222
105 Perampanel 2件: Fycompa; PERAMPANEL1件: D08964 4件: GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		16件: Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬3件: 2, 6, 144
106 Phenylbutyric acid 4件: 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium phenylbutyrate---14件: 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338
107 Phosphate ion 1件: Phosphate---33件: 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
108 Pimozide 1件: Pimozide1件: D00560 2件: ADRA2A,
DRD2 💬		9件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 2
109 Pioglitazone 1件: Pioglitazone2件: D00945 ,
D08378 		1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
110 Pleconaril 1件: PLECONARIL1件: D05528 --1件: 2
111 Pramipexole 7件: Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL2件: D00559 ,
D05575 		3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 20
112 Prednisone 3件: Prednisona; PREDNISONE; RAYOS1件: D00473 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
113 Pridopidine 1件: Pridopidine1件: D09953 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 8
114 Pyrazole 2件: 1H-Pyrazol; Pyrazole---6件: 2, 28, 46, 58, 75, 154
115 Pyrimethamine 2件: Daraprim; Pyrimethamine1件: D00488 --11件: 2, 4, 6, 13, 19, 46, 51, 65, 96, 97, 265
116 Quinidine 4件: Nuedexta; Quinidina; Quinidine; Quinidine Sulfate4件: D00642 ,
D00643 ,
D02272 ,
D08458 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬3件: 2, 8, 13
117 Rabeprazole 1件: Rabeprazole2件: D00724 ,
D08463 		2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 2, 51
118 Ranolazine 3件: RANEXA; Ranolazina; Ranolazine2件: D05700 ,
D05701 		--6件: 2, 58, 86, 96, 113, 114
119 Rasagiline 4件: AZILECT; Rasagilina; Rasagiline; Rasagiline mesylate3件: D02562 ,
D08469 ,
D10829 		1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬7件: 2, 5, 6, 13, 17, 58, 66
120 Ravulizumab 2件: RAVULIZUMAB; Ultomiris1件: D11054 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬7件: 2, 11, 13, 50, 62, 66, 109
121 Reldesemtiv 2件: CK-2127107; Reldesemtiv1件: D11363 1件: TNNC2 💬1件: Calcium signaling pathway 💬2件: 2, 3
122 Resveratrol 1件: Resveratrol---6件: 2, 8, 18, 89, 113, 299
123 Ribavirin 2件: Copegus; RIBAVIRIN1件: D00423 --2件: 2, 96
124 Riluzole 2件: RILUTEK; Riluzole1件: D00775 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
125 Ritonavir 2件: Norvir; Ritonavir1件: D00427 --3件: 2, 86, 265
126 Ropinirole 3件: REQUIP; ROPINIROLE; Ropinirole Hydrochloride2件: D00784 ,
D08489 		3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 2, 6, 74, 309
127 Scopolamine 1件: Scopolamine1件: D00138 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 2
128 Serine 2件: L-Serine; Serine1件: D00016 --4件: 2, 6, 86, 96
129 Serotonin 1件: Serotonin---3件: 2, 96, 97
130 Sirolimus 3件: RAPAMUNE; Rapamycin; Sirolimus1件: D00753 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬41件: 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
131 Sodium lauryl sulfate 0件: 1件: D01045 --1件: 2
132 Somatotropin 17件: Genotropin; Growth Hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; SOMATROPIN; SOMATROPINA; Zomacton1件: D02691 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬23件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
133 Sulfate ion 1件: Sulfate---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 218, 222, 226, 265, 296, 297, 299
134 Sulpiride 0件: 2件: D01226 ,
D08549 		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 2, 6, 17, 46, 70
135 Tacrolimus 2件: Prograf; Tacrolimus2件: D00107 ,
D08556 		5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
136 Talampanel 1件: Talampanel1件: D02696 4件: GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		16件: Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬2件: 2, 6
137 Tamoxifen 2件: Tamoxifen; TAMOXIFEN CITRATE2件: D00966 ,
D08559 		2件: ESR1,
ESR2 💬		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬4件: 2, 86, 113, 227
138 Tauroursodeoxycholic acid 2件: Tauroursodeoxycholic acid; TUDCA1件: D11836 --4件: 2, 13, 93, 299
139 Tenofovir 1件: Tenofovir1件: D06074 --6件: 2, 13, 25, 93, 265, 325
140 Tenofovir alafenamide 1件: Tenofovir alafenamide1件: D10428 --2件: 2, 13
141 Testosterone 1件: Testosterone6件: D00075 ,
D00957 ,
D00958 ,
D00959 ,
D06085 ,
D06087 		1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265
142 Thalidomide 1件: THALIDOMIDE1件: D00754 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
143 Tirasemtiv 1件: Tirasemtiv1件: D10327 --1件: 2
144 Tocilizumab 3件: Actemra; ROACTEMRA; TOCILIZUMAB1件: D02596 1件: IL6R 💬12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬21件: 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
145 Tofersen 1件: Tofersen1件: D11811 1件: SOD1 💬8件: Amyotrophic lateral sclerosis, Chemical carcinogenesis - reactive oxygen species, Huntington disease, Longevity regulating pathway - multiple species, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Peroxisome, Prion disease 💬1件: 2
146 Trametinib 2件: Mekinist; Trametinib1件: D10175 2件: MAP2K1,
MAP2K2 💬		89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬4件: 2, 34, 279, 280
147 Trazodone 1件: Trazodone2件: D00820 ,
D08626 		4件: HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬		6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 2
148 Trehalose 2件: Cabaletta; Trehalose---3件: 2, 18, 113
149 Tretinoin 5件: ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID1件: D00094 3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231
150 Triheptanoin 1件: TRIHEPTANOIN1件: D11465 --10件: 2, 8, 65, 149, 156, 248, 256, 257, 317, 324
151 Trimetazidine 1件: Trimetazidine1件: D08642 --3件: 2, 58, 86
152 TRO19622 1件: TRO19622---3件: 2, 3, 13
153 Ubidecarenone 3件: Coenzyme Q-10; Coenzyme Q10; CoQ101件: D01065 --13件: 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 193, 214, 215
154 Umbilical Cord Blood Hematopoietic Stem Cells 1件: Cord blood therapy---2件: 2, 6
155 Valproic acid 3件: Valproate; VALPROATE SODIUM; Valproic acid1件: D00399 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
156 Verdiperstat 1件: Verdiperstat1件: D11684 1件: MPO 💬5件: Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬3件: 2, 17, 127
157 Vitamin E 2件: Alpha-tocopherol; Vitamin E1件: D02331 --12件: 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317
158 Water 9件: AVONEX; ENBREL; Glucagon; Hiberix; Indocyanine Green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION1件: D00001 --23件: 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299
159 Zilucoplan 1件: ZILUCOPLAN---3件: 2, 11, 62
160 Zinc 3件: Nicotinamide; Wilzin; Zinc---4件: 2, 113, 171, 299