Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Synonym: Dometuss-NR)		5件: Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬18件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Amlodipine
(Synonym: Nra-amlodipine)		1件: Amlodipine3件: D00615 ,
D02914 ,
D07450 		4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 13, 51, 67, 298
3 Atorvastatin
(Synonym: Nra-atorvastatin)		3件: Atorvastatin; Atorvastatin calcium; Lipitor3件: D00258 ,
D00887 ,
D07474 		1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
4 Azithromycin
(Synonym: Nra-azithromycin)		5件: Azithromycin; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; Zithromax3件: D02134 ,
D06390 ,
D07486 		--6件: 13, 84, 85, 96, 228, 299
5 Biotin
(Synonym: Nrg Plus Liq)		4件: BIOTIN; Biotina; D-BIOTIN; Vitamin B71件: D00029 --5件: 2, 8, 10, 13, 20
6 Celecoxib
(Synonym: Nra-celecoxib)		2件: Celebrex; Celecoxib1件: D00567 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
7 Cetirizine
(Synonym: Nra-cetirizine)		3件: CETIRIZINA; Cetirizine; CETIRIZINE HYDROCHLORIDE2件: D00664 ,
D07662 		1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 28, 35, 300
8 Chlorpheniramine
(Synonym: Dometuss-NR)		1件: Clorfenamina4件: D00665 ,
D00668 ,
D07398 ,
D07803 		1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
9 Cholecalciferol
(Synonym: Nrg Plus Liq)		5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D31件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬25件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
10 Choline
(Synonym: Nrg Plus Liq)		1件: Choline1件: D07690 --4件: 93, 171, 193, 299
11 Ciprofloxacin
(Synonym: Nra-ciprofloxacin)		2件: Ciprofloxacin; CIPROFLOXACIN HYDROCHLORIDE2件: D00186 ,
D02216 		--5件: 2, 60, 96, 97, 299
12 Citalopram
(Synonym: Nra-citalopram)		1件: Citalopram2件: D00822 ,
D07704 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127
13 Clindamycin
(Synonym: Nra-clindamycin)		2件: CLINDAMYCIN; Dalacin C phosphate4件: D00277 ,
D01073 ,
D01990 ,
D02132 		--2件: 46, 299
14 Clopidogrel
(Synonym: Nra-clopidogrel)		1件: Clopidogrel4件: D00769 ,
D07729 ,
D10823 ,
D10824 		1件: P2RY12 💬1件: Platelet activation 💬2件: 49, 86
15 Cyanocobalamin
(Synonym: Nrg Plus Liq)		2件: Cianocobalamina; Vitamin B124件: D00166 ,
D03615 ,
D03616 ,
D03617 		--5件: 6, 13, 201, 229, 299
16 Dextromethorphan
(Synonym: Guaifenesin-DM Nr)		4件: Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta3件: D00848 ,
D03742 ,
D03744 		6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
17 Duloxetine
(Synonym: Nra-duloxetine)		3件: CYMBALTA; Duloxetine; Duloxetine hydrochloride2件: D01179 ,
D07880 		2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 13
18 Escitalopram
(Synonym: Nra-escitalopram)		3件: Citalopram; Escitalopram; Escitalopram oxalate3件: D02567 ,
D07704 ,
D07913 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬3件: 2, 6, 13
19 Ethanol
(Synonym: Nrl Pure Daily Hand Sanitizer)		3件: Alcohol; Ethanol; Prednisone4件: D00068 ,
D02798 ,
D04855 ,
D06542 		--7件: 13, 51, 58, 97, 279, 280, 298
20 Ezetimibe
(Synonym: Nra-ezetimibe)		2件: Ezetimibe; Ezetrol1件: D01966 1件: NPC1L1 💬1件: Fat digestion and absorption 💬4件: 49, 79, 93, 260
21 Fluoxetine
(Synonym: Nra-fluoxetine)		5件: Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC2件: D00326 ,
D00823 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬6件: 13, 17, 78, 86, 179, 206
22 Hydrochlorothiazide
(Synonym: Nra-telmisartan Hctz)		2件: Esidrix; Hydrochlorothiazide1件: D00340 1件: SLC12A3 💬-4件: 13, 67, 225, 235
23 Hydroxychloroquine
(Synonym: Nra-hydroxychloroquine)		3件: Hydroxychloroquine; Hydroxychloroquine Sulfate; PLAQUENIL1件: D08050 --27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
24 Inositol
(Synonym: Nrg Plus Liq)		1件: Inositol1件: D08079 --2件: 96, 97
25 Lacosamide
(Synonym: Nra-lacosamide)		1件: Lacosamide1件: D07299 2件: SCN3A,
SCN9A 💬		1件: Taste transduction 💬3件: 2, 46, 149
26 Letrozole
(Synonym: Nra-letrozole)		1件: Letrozole1件: D00964 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬2件: 81, 89
27 Levetiracetam
(Synonym: Nra-levetiracetam)		2件: KEPPRA; Levetiracetam1件: D00709 1件: SV2A 💬1件: ECM-receptor interaction 💬5件: 2, 4, 6, 13, 307
28 Montelukast
(Synonym: Nra-montelukast)		3件: Montelukast; MONTELUKAST SODIUM; Singulair2件: D00529 ,
D08229 		1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬8件: 6, 13, 46, 61, 63, 85, 98, 228
29 Nicotinamide
(Synonym: Nrg Plus Liq)		4件: Ginseng; Multivitamin; Niacinamide; NICOTINAMIDE1件: D00036 --11件: 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
30 Omeprazole
(Synonym: Nra-omeprazole)		5件: Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM4件: D00455 ,
D01207 ,
D05259 ,
D05261 		2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
31 Pantoprazole
(Synonym: Nra-pantoprazole)		1件: PANTOPRAZOLE2件: D02593 ,
D05353 		2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 13, 65
32 Paroxetine
(Synonym: Nra-paroxetine)		1件: Paroxetine4件: D02260 ,
D02362 ,
D05374 ,
D05375 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 6, 13, 46, 85
33 Perindopril
(Synonym: Nra-perindopril)		2件: Coversyl; Perindopril2件: D00624 ,
D03753 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 58, 113, 167, 222
34 Phenylephrine
(Synonym: Brontuss SF-NR)		1件: Phenylephrine2件: D00511 ,
D08365 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
35 Pregabalin
(Synonym: Nra-pregabalin)		2件: Lyrica; Pregabalin1件: D02716 4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬5件: 13, 36, 46, 70, 298
36 Pyridoxine
(Synonym: Nrg Plus Liq)		2件: Pyridoxine; Vitamin B62件: D02179 ,
D08454 		--5件: 6, 93, 145, 206, 320
37 Quetiapine
(Synonym: Nra-quetiapine XR)		2件: Quetiapine; Seroquel2件: D00458 ,
D08456 		2件: DRD2,
HTR2A 💬		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬2件: 6, 13
38 Ramipril
(Synonym: Nra-ramipril)		1件: Ramipril1件: D00421 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 46, 49, 66, 67, 113, 218, 257
39 Rosuvastatin
(Synonym: Nra-rosuvastatin)		3件: Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM2件: D01915 ,
D08492 		1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
40 Sertraline
(Synonym: Nra-sertraline)		1件: Sertraline2件: D00825 ,
D02360 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 206
41 Sildenafil
(Synonym: Nra-sildenafil)		6件: Mysildecard; Revatio; SILDENAFIL; Sildenafil Citrate; SILDENAFILO; Viagra2件: D02229 ,
D08514 		1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
42 Sodium fluoride
(Synonym: Nrg Apf)		2件: Beam; Sodium fluoride1件: D00943 --1件: 51
43 Tadalafil
(Synonym: Nra-tadalafil)		4件: Adcirca; Cialis; Tadalafil; TADALAFILO1件: D02008 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 84, 86, 113, 210
44 Telmisartan
(Synonym: Nra-telmisartan)		1件: Telmisartan1件: D00627 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 66, 67
45 Thiamine
(Synonym: Nrg Plus Liq)		2件: THIAMINE; Vitamin B11件: D08580 --5件: 8, 13, 93, 145, 265
46 Tramadol
(Synonym: Nra-tramadol/acet)		2件: Tramadol; Ultracet2件: D01355 ,
D08623 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 46, 70, 78, 226, 271
47 Vitamin A
(Synonym: Nrg Plus Liq)		1件: Vitamin A2件: D00069 ,
D06543 		2件: RARA,
RARB 💬		8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬3件: 13, 53, 90
48 Zolmitriptan
(Synonym: Nra-zolmitriptan)		1件: Zolmitriptan1件: D00415 2件: HTR1B,
HTR1D 💬		4件: Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 6
49 Zopiclone
(Synonym: Nra-zopiclone)		1件: Zopiclone1件: D01372 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6