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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
118F-AV-1451----[3] 5, 7, 127
218F-FDG[1] Fludeoxyglucose (18F)---[13] 5, 6, 7, 8, 13, 41, 46, 53, 84, 85, 96, 127, 300
318F-RO6958948----[3] 5, 7, 127
44-benzyl-2-naphtalen-1-yl-1,2,4-thiadiazolidine-3,5-dione----[1] 5
59-CIS, 12-CIS-11,11-D2-LINOLEIC ACID ETHYL ESTER[1] Linoleic acid---[2] 2, 5
6[18F] APN-1607----[1] 5
7[18F]-PI2620----[1] 5
8[18F]Florbetapir----[1] 5
9[18F]MNI-815 (MNI-815)----[1] 5
10[18F]MNI-952----[1] 5
11[18F]MNI-958----[1] 5
12[18F]T807 ([18F]MNI-777)----[2] 5, 6
13[F18]-FDDNP----[1] 5
14AB1010----[6] 2, 5, 6, 13, 46, 96
15ABBV-8E12----[2] 5, 7
16AL----[10] 5, 7, 13, 28, 51, 67, 86, 97, 114, 127
17AL-108----[1] 5
18Alpha-lipoic acid and L-acetyl carnitine[2] Levocarnitine,
Lipoic acid		[5] D00048 ,
D00086 ,
D02030 ,
D02176 ,
D04713 		--[1] 5
19Anti-Parkinson medication----[5] 5, 6, 7, 8, 17
20Antisense oligonucleotide----[1] 5
21Apomorphine[1] Apomorphine[2] D02004 ,
D07460 		[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7
22ASK Nr. 21972----[1] 5
23Azilect[1] Rasagiline[3] D02562 ,
D08469 ,
D10829 		[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[4] 2, 5, 6, 17
24AZP2006 oral solution----[1] 5
25Bepranemab----[1] 5
26BIIB092----[3] 5, 7, 127
27BMS-986168[1] Gosuranemab[1] D11293 [1] MAPT 💬[4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[1] 5
28BMS986168----[1] 5
29BOTULINUM TOXIN TYPE A[1] Botulinum toxin type A[1] D00783 [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[10] 2, 5, 6, 7, 13, 15, 17, 70, 113, 149
30Brain PET scan----[3] 5, 7, 127
31Carnitine[1] Levocarnitine[3] D02030 ,
D02176 ,
D04713 		--[9] 5, 13, 58, 86, 96, 97, 265, 298, 316
32Coenzym Q10 Nanodispersion----[1] 5
33Coenzym Q10, Ubiquinon, Ubichinon----[1] 5
34Coenzyme Q10[1] Ubidecarenone[1] D01065 --[12] 2, 5, 6, 8, 10, 18, 46, 57, 113, 193, 214, 215
35CoQ10----[3] 5, 6, 8
36Creatine[1] Creatine---[16] 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 113, 156, 201, 256
37DaTSCAN[1] Ioflupane I-123---[4] 2, 5, 6, 17
38DaTSCAN™ Ioflupane (123I) Injection[1] Ioflupane I-123---[3] 5, 6, 17
39Davunetide[1] Davunetide[1] D09401 --[3] 5, 7, 127
40Davunetide (AL-108, NAP)[1] Davunetide[1] D09401 --[3] 5, 7, 127
41Deep Brain Stimulation----[5] 5, 6, 7, 8, 17
42Diagnostic Test: [18F]-RO6958948----[5] 5, 6, 7, 17, 127
43Diagnostic Test: Elecsys (Roche) Abeta42, Ttau and Ptau----[5] 5, 6, 7, 17, 127
44Diagnostic Test: Flutemetamol F18 Injection[2] Flutemetamol,
Flutemetamol (18F)		---[5] 5, 6, 7, 17, 127
45Diagnostic Test: Lumipulse (Fujirebio) Abeta42, Ttau and Ptau----[5] 5, 6, 7, 17, 127
46Donepezil[1] Donepezil[2] D00670 ,
D07869 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
47Droxidopa[1] Droxidopa[1] D01277 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170
48Emeramide[1] Emeramide---[2] 5, 17
49Example[1] Hydroxide ion---[1] 5
50Exelon 1,5 mg Hartkapseln[1] Rivastigmine[2] D02558 ,
D03822 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[1] 5
51Exelon 3,0 mg Hartkapseln[1] Rivastigmine[2] D02558 ,
D03822 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[1] 5
52Exelon 6,0 mg Hartkapseln[1] Rivastigmine[2] D02558 ,
D03822 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[1] 5
53F-18----[2] 5, 127
54F-18 AV 1451----[1] 5
55Fasudil[1] Fasudil[1] D07941 [2] ROCK1,
ROCK2 💬		[23] Axon guidance, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 2, 5, 7, 51
56Flortaucipir[1] Flortaucipir[1] D11210 [1] MAPT 💬[4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[3] 5, 7, 127
57Flortaucipir F18[1] Flortaucipir[1] D11210 [1] MAPT 💬[4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[3] 5, 7, 127
58Flutemetamol[1] Flutemetamol (18F)---[5] 5, 6, 7, 17, 127
59Flutemetamol F18[1] Flutemetamol (18F)---[5] 5, 6, 7, 17, 127
60Fresh Frozen Plasma----[1] 5
61GDNF & Synchro Med Infusion System----[1] 5
62Gold[1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318
63Hydrogen[1] Hydrogen---[7] 5, 6, 13, 17, 83, 97, 226
64Leucine[1] Leucine[1] D00030 --[11] 5, 6, 7, 19, 65, 96, 97, 127, 283, 284, 299
65Linoleic acid[1] Linoleic acid---[4] 2, 5, 13, 299
66Lipoic acid[1] Lipoic acid[2] D00048 ,
D00086 		--[5] 2, 5, 13, 14, 20
67Lithium[1] Lithium citrate[1] D04749 --[5] 2, 5, 6, 7, 8
68MASITINIB[1] Masitinib[1] D10229 [1] KIT 💬[11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96
69Masitinib 100mg[1] Masitinib[1] D10229 [1] KIT 💬[11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[2] 2, 5
70Masitinib 200mg[1] Masitinib[1] D10229 [1] KIT 💬[11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[2] 2, 5
71MASITINIB MESYLATE[1] Masitinib[1] D10229 [1] KIT 💬[11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96
72N1,N3-BIS(2-MERCAPTOETHYL) ISOPHTHALAMIDE----[2] 5, 17
73NBMI----[2] 5, 17
74Niacinamide[1] Nicotinamide[1] D00036 --[4] 5, 6, 13, 67
75Nitrogen[1] Nitrogen[1] D00083 --[6] 5, 6, 17, 171, 211, 299
76NP031112----[1] 5
77NP031112 600mg----[1] 5
78NP031112 800mg----[1] 5
79NT 101----[4] 5, 6, 7, 17
80Other: 13C6 Leucine[1] Leucine[1] D00030 --[3] 5, 7, 127
81Placebo----[27] 3, 5, 6, 13, 14, 37, 40, 46, 49, 50, 51, 53, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276
82Pyruvate, creatine, niacinamide[2] Creatine,
Nicotinamide		[1] D00036 --[1] 5
83Raclopride[1] Raclopride---[4] 5, 6, 7, 17
84Radiopharmaceuticals----[1] 5
85Rasagilin----[2] 5, 6
86Rasagiline[1] Rasagiline[3] D02562 ,
D08469 ,
D10829 		[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[4] 2, 5, 6, 17
87RASAGILINE MESILATE[1] Rasagiline[3] D02562 ,
D08469 ,
D10829 		[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[3] 2, 5, 6
88RILUZOLE[1] Riluzole[1] D00775 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
89RIVASTIGMINE[1] Rivastigmine[2] D02558 ,
D03822 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13
90RT001----[3] 2, 5, 120
91Salsalate[1] Salsalate[1] D00428 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 5
92Single dose C2N-8E12----[1] 5
93Stem cell therapy----[1] 5
94Sugar pill----[8] 5, 6, 49, 67, 70, 86, 206, 210
95Suvorexant[1] Suvorexant[1] D10082 [2] HCRTR1,
HCRTR2 💬		[1] Neuroactive ligand-receptor interaction 💬[3] 5, 6, 13
96Tideglusib[1] Tideglusib---[2] 5, 113
97Tolfenamic Acid[1] Tolfenamic acid[1] D01183 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 5
98TPI 287 2 mg/m2----[2] 5, 7
99TPI-287 20 mg/m2----[2] 5, 7
100TPI-287 6.3 mg/m2----[2] 5, 7
101TPN-101, 100 mg/day----[1] 5
102TPN-101, 200 mg/day----[1] 5
103TPN-101, 400 mg/day----[3] 2, 5, 127
104Trihexyphenidyl[1] Trihexyphenidyl[2] D00787 ,
D08638 		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6
105Ubidecarenon----[1] 5
106UCB0107 (bepranemab)----[1] 5
107Valproic Acid[1] Valproic acid[1] D00399 [7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[10] 3, 5, 26, 34, 65, 89, 90, 222, 256, 331
108Vizamyl[1] Flutemetamol (18F)---[3] 5, 7, 127
109Vizamyl (flutemetamol(F-18))[1] Flutemetamol (18F)---[3] 5, 7, 127
110Water[1] Water[1] D00001 --[23] 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299
111Xeomin[1] Botulinum toxin type A[1] D00783 [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[7] 5, 6, 7, 13, 15, 17, 113
112Zoledronic acid[1] Zoledronic acid[4] D01968 ,
D06378 ,
D06379 ,
D08689 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[12] 5, 6, 13, 17, 46, 93, 95, 96, 270, 274, 299, 333
113Zoledronic Acid 5Mg/Bag 100Ml Inj[1] Zoledronic acid[4] D01968 ,
D06378 ,
D06379 ,
D08689 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 5, 6, 17
114Zolpidem[1] Zolpidem[2] D00706 ,
D08690 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 5, 6, 46