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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1ABP 959----[1] 62
2ABP 959 - biosimilar to eculizumab[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
3ABP 959 - proposed biosimilar to eculizumab[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
4ACH-0144471----[2] 62, 222
5ACH-0145228----[1] 62
6Act-HiB[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---[4] 14, 61, 62, 222
7ACT-HIB Polvere e solvente per soluzione iniettabile in siringa preriempita 0,5 ml[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---[2] 61, 62
8ActHIB[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---[2] 62, 66
9ACTHIB - POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONCINO POLVERE+1 SIRINGA PRERIEMPITA SOLVENTE 0.5 ML[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---[2] 62, 66
10Allogeneic Bone Marrow Transplantation----[9] 60, 62, 65, 96, 164, 283, 284, 285, 286
11Allogeneic hematopoietic stem cell transplantation----[8] 28, 51, 60, 62, 65, 164, 284, 285
12Allogeneic stem cell transplantation----[5] 19, 20, 49, 62, 84
13ALN-62643----[2] 62, 109
14ALN-CC5----[4] 11, 62, 66, 109
15ALXN1102----[1] 62
16ALXN1103----[1] 62
17ALXN1210----[7] 2, 11, 13, 50, 62, 66, 109
18ALXN2040----[1] 62
19ALXN2040 (ACH-0144471)----[1] 62
20ALXN2050----[2] 11, 62
21Anti-C5 antibody----[4] 11, 14, 62, 109
22Anti-Thymocyte Globulin----[18] 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 164, 283, 284, 285
23APL-2----[5] 2, 61, 62, 66, 222
24ARO-C3----[2] 62, 66
25BCD-148----[1] 62
26BCX9930----[3] 62, 66, 222
27BCX9930 hydrochloride----[3] 62, 66, 222
28BCX9930 monotherapy----[1] 62
29Bexsero[1] Neisseria meningitidis serogroup b nhba fusion protein antigen---[6] 11, 13, 61, 62, 66, 222
30BEXSERO - SOSPENSIONE INIETTABILE - USO INTRAMUSCOLARE - SIRINGA P[1] Neisseria meningitidis serogroup b nhba fusion protein antigen---[1] 62
31BEXSERO – Sospensione iniettabile – Siringa preriempita[1] Neisseria meningitidis serogroup b nhba fusion protein antigen---[2] 61, 62
32Bryostatin 1[1] Bryostatin 1---[1] 62
33C5 inh MAb, SKY59, RO/CH7092230----[2] 62, 109
34C5 Inhibitor----[1] 62
35Campath[1] Alemtuzumab[1] D02802 [1] CD52 💬-[12] 19, 20, 49, 51, 60, 62, 65, 164, 234, 283, 285, 326
36Campath, Chemo and/or TBI Allo SCT[1] Alemtuzumab[1] D02802 [1] CD52 💬-[3] 60, 62, 283
37Cemdisiran[1] Cemdisiran---[4] 11, 62, 66, 109
38COVERSIN[1] Nomacopan[1] D11473 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[2] 62, 109
39CROVALIMAB[1] Crovalimab[1] D11696 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[2] 62, 109
40Cyclophosphamide[1] Cyclophosphamide[2] D00287 ,
D07760 		--[45] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
41Cyclosporin[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[17] 38, 46, 49, 50, 53, 56, 60, 62, 63, 93, 95, 97, 113, 164, 222, 274, 326
42Cyclosporin A[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[11] 46, 49, 53, 56, 60, 62, 63, 93, 95, 113, 164
43Cyclosporin A+Glucocorticoids[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[2] 60, 62
44Cyclosporine[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
45Cytoreductive regimen followed by a CD34+E- selected allogeneic stem cell transplant----[1] 62
46DANICOPAN[1] Danicopan[1] D11641 [1] CFD 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[2] 62, 222
47Danicopan (ALXN2040)[1] Danicopan[1] D11641 [1] CFD 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[1] 62
48Dextran[1] Dextran[1] D00060 --[5] 2, 62, 79, 96, 97
49ECULIZUMAB[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 11, 13, 14, 61, 62, 109, 222
50Elizaria®----[2] 62, 109
51Fc- and CDR-modified humanised monoclonal antibody against C5----[3] 11, 62, 109
52Filgrastim[1] Filgrastim[1] D03235 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[28] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331
53Fludarabine[1] Fludarabine[2] D01907 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[18] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
54Fludarabine phosphate[2] Fludarabine,
Phosphate ion		[2] D01907 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[12] 28, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286
55G-CSF[1] Filgrastim[1] D03235 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[16] 2, 6, 11, 13, 16, 47, 49, 51, 60, 62, 65, 85, 96, 284, 285, 331
56Gelatin[1] Gelatin[2] D00115 ,
D06892 		--[5] 28, 62, 78, 97, 269
57Glucocorticoids----[8] 40, 41, 43, 44, 60, 62, 75, 300
58H5G1.1-mAb----[3] 13, 50, 62
59HAEMOPHILUS INFLUENZAE----[3] 61, 62, 66
60Hiberix[1] Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen---[4] 13, 61, 62, 66
61HIBERIX - POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE PER USO INTRAMUSCOLARE 1 FLACONCINO DI POLVERE + 1 SIRINGA PRERIEMPITA DI SOLVENTE DA 0.5 ML[1] Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen---[3] 61, 62, 66
62Human monoclonal antibody directed against complement 5 protein----[1] 62
63Iptacopan[1] Iptacopan[1] D12251 [1] CFB 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[5] 61, 62, 66, 109, 222
64Iptacopan (LNP023)[1] Iptacopan[1] D12251 [1] CFB 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[1] 62
65Iron Dextran[2] Dextran,
Iron Dextran		[2] D00060 ,
D02141 		--[1] 62
66Iron sucrose[2] Iron sucrose,
Sucrose		[2] D00025 ,
D04616 		--[3] 62, 96, 97
67L04AA25----[1] 62
68Lapine T-Lymphocyte Immune Globulin[1] Antithymocyte immunoglobulin (rabbit)---[4] 62, 65, 283, 286
69Levamisole[1] Levamisole[2] D00750 ,
D08114 		--[3] 60, 61, 62
70Levamisole+cyclosporin A+Glucocorticoids[2] Cyclosporine,
Levamisole		[3] D00184 ,
D00750 ,
D08114 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[2] 60, 62
71LFG316----[1] 62
72LNP023----[5] 61, 62, 66, 109, 222
73LNP023 HYDROCHLORIDE SALT----[1] 62
74Melphalan[1] Melphalan[1] D00369 --[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299
75Menveo[1] Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine---[6] 11, 13, 61, 62, 66, 222
76MENVEO - POLV.E SOLUZ.PER SOLUZ. INIETT.-USO INTRAMUSCOLARE-COMP. CONIUG.LIOFILIZZ.MENA:FLAC.(VETRO) COMP. GONIUG.LIQUI.MENCWY:FLAC.(VETRO)-1 FLAC+1FLAC[1] Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine---[2] 62, 66
77MENVEO – Polvere e soluzione per soluzione iniettabile[1] Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine---[2] 61, 62
78Methotrexate[1] Methotrexate[2] D00142 ,
D02115 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
79Methylprednisolone[1] Methylprednisolone[6] D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
80Miltenyi Biotec CliniMACS----[2] 62, 326
81Miltenyi CliniMACS----[3] 62, 65, 285
82Mycophenolate[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
83Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[4] D00752 ,
D05094 ,
D05095 ,
D05096 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
84Myeloablative Preparative Regimen----[3] 62, 65, 284
85NO----[12] 6, 13, 46, 58, 62, 86, 96, 97, 222, 226, 299, 321
86Nonmyeloablative allogeneic hematopoietic stem cell transplantation----[6] 28, 51, 60, 62, 65, 285
87Other: Blood collection for measurement of eculizumab peak concentrations[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
88Other: Laboratory Biomarker Analysis----[21] 11, 13, 14, 26, 28, 34, 49, 51, 60, 62, 65, 89, 96, 97, 205, 232, 283, 284, 285, 298, 331
89Other: Peripheral Blood Stem Cells----[2] 60, 62
90Other: Pharmacological Study----[7] 28, 34, 62, 74, 89, 232, 331
91Other: Quality-of-Life Assessment----[9] 34, 36, 51, 62, 65, 96, 283, 286, 298
92Other: Standard of care (SOC)----[1] 62
93PEGCETACOPLAN[1] Pegcetacoplan[1] D11613 [1] C3 💬[17] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[3] 2, 62, 222
94Pegcetacoplan (APL-2)[1] Pegcetacoplan[1] D11613 [1] C3 💬[17] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[2] 2, 62
95Peripheral Blood Stem Cell Transplantation----[12] 11, 13, 14, 28, 51, 60, 62, 65, 283, 284, 285, 286
96Phosphate[1] Phosphate ion---[33] 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
97PNEUMOVAX – Soluzione iniettabile in siringa preriempita da 0,5 ml----[2] 62, 66
98Pozelimab[1] Pozelimab[1] D11477 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[2] 11, 62
99RA101495----[1] 62
100RA101495 sodium----[1] 62
101Radiation: total-body irradiation----[9] 28, 51, 60, 62, 65, 96, 283, 284, 285
102RAVULIZUMAB[1] Ravulizumab[1] D11054 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 2, 11, 13, 50, 62, 66, 109
103Reduced Intensity Preparative Regimen----[3] 62, 65, 284
104Reduced Toxicity Ablative Regimen----[3] 62, 65, 284
105REGN3918----[2] 11, 62
106RO7112689----[1] 62
107RO7112689/F01----[1] 62
108RO7112689/F03-01----[2] 62, 109
109RO7112689/F03-03----[1] 62
110RO7112689/F03-10----[2] 62, 109
111RVA576----[3] 62, 109, 162
112RVA576 (COVERSIN)[1] Nomacopan[1] D11473 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[2] 62, 109
113Sargramostim[1] Sargramostim[1] D05803 [1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[7] 6, 28, 60, 62, 96, 229, 285
114SB12 (proposed eculizumab biosimilar)[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
115Sirolimus[1] Sirolimus[1] D00753 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[36] 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 89, 98, 127, 137, 157, 158, 192, 222, 277, 278, 279, 280, 281, 283, 285, 331
116Solaris----[2] 62, 109
117SOLIRIS[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 11, 13, 14, 61, 62, 109, 222
118Soliris (eculizumab)[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
119SOLIRIS - 300 MG CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO 1 FLACONCINO (VETRO) 30 ML (10 MG/ML)[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 13, 62, 109
120Soliris 300[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
121Soliris 300 mg concentrate for solution for infusion[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
122Soliris 300mg/30ml[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
123Soliris®[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
124SOLIRIS® (eculizumab) injection, for intravenous use[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
125Stem Cell Transplantation----[13] 13, 19, 20, 46, 51, 60, 62, 65, 90, 125, 164, 234, 326
126Sterile Normal Saline (0.9% NaCl)----[3] 62, 234, 254
127Sucrose[1] Sucrose[1] D00025 --[3] 62, 96, 97
128Synthetic 15-amino-acid macrocyclic peptide----[1] 62
129Synthetic 15-amino-acid macrocyclic peptide acylated with a ethyleneglycol24----[1] 62
130Synthetic 15-amino-acid macrocyclic peptide acylated with a ethyleneglycol24 palmitoylated linker----[1] 62
131Synthetic 15-amino-acid macrocyclic peptide acylated with a polyethyleneglycol palmitoylated linker----[1] 62
132Systematic chemotherapy and antibodies----[1] 62
133Systemic chemotherapy and antibodies----[2] 62, 326
134Tacrolimus[1] Tacrolimus[2] D00107 ,
D08556 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
135TREOSULFAN[1] Treosulfan[1] D07253 --[6] 13, 19, 62, 65, 283, 286
136Tretinoin[1] Tretinoin[1] D00094 [3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[3] 2, 62, 75
137Ultomiris[1] Ravulizumab[1] D11054 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[6] 2, 11, 13, 50, 62, 66
138ULTOMIRIS - 300 MG - CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - FLACONCINO (VETRO) 3 ML (100 MG / ML) - 1 FLACONCINO[1] Ravulizumab[1] D11054 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
139Ultomiris 300mg/30ml[1] Ravulizumab[1] D11054 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
140VACCINO CONTRO IL MEMINGOCOCCO DI GRUPPO B----[3] 61, 62, 66
141VACCINO HAEMOPHILUS INFLUENZAE B CONIUGATO CON TOSSOIDETETANICO----[2] 61, 62
142VACCINO PNEUMOCOCCICO----[2] 62, 66
143VACCINO POLISACCARIDICO ANTI-MENINGOCOCCICO (A.C.Y E W-135)----[3] 61, 62, 66
144VARI----[2] 62, 274
145Zilucoplan[1] Zilucoplan---[3] 2, 11, 62
146Zilucoplan (RA101495)[1] Zilucoplan---[2] 11, 62
147 LNP023 HYDROCHLORIDE SALT----[5] 61, 62, 66, 109, 222