Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(2)-epigallocatechin-3-gallate (EGCG)[2] Epigallocatechin,
Epigallocatechin gallate		---[1] 8
218F-FDG[1] Fludeoxyglucose (18F)---[13] 5, 6, 7, 8, 13, 41, 46, 53, 84, 85, 96, 127, 300
320 mg BID of PF-02545920----[1] 8
420mg daily citalopram[1] Citalopram[2] D00822 ,
D07704 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
55-Chloro-1,2-dihydro-N-ethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-3-quinolinecarboxamide sodium----[1] 8
6[123I]MNI-420----[2] 6, 8
7[18F]FPEB----[3] 6, 8, 206
8ACR16----[1] 8
9ACR16 10 mg----[1] 8
10ACR16 22.5 mg----[1] 8
11ACR16 45 mg----[1] 8
12ACR16 hydrochloride, ASP2314 hydrochloride, FR310826----[1] 8
13ADENO-ASSOCIATED VIRUS SEROTYPE 5 ENCODING A MICRORNA TARGETED TO HUMAN HUNTINGTIN GENE----[1] 8
14AFQ056----[3] 6, 8, 206
15Alprazolam[1] Alprazolam[1] D00225 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 8, 75
16AMANTADINE[1] Amantadine[2] D00777 ,
D07441 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[4] 6, 8, 13, 127
17AMT----[4] 8, 46, 97, 321
18AMT-130----[1] 8
19Anti-Parkinson medication----[5] 5, 6, 7, 8, 17
20ANX005----[3] 2, 8, 61
21Atomoxetine[1] Atomoxetine[2] D02574 ,
D07473 		[1] SLC6A2 💬[1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17
22Autologous Stem Cell----[1] 8
23Benerva----[1] 8
24Bevantolol[1] Bevantolol---[1] 8
25BEVANTOLOL HYDROCHLORIDE[1] Bevantolol---[1] 8
26BioStamp nPoint device----[1] 8
27BIOTIN[1] Biotin[1] D00029 --[5] 2, 8, 10, 13, 20
28Biotina[1] Biotin[1] D00029 --[2] 8, 13
29Blood sample----[18] 8, 13, 46, 49, 51, 53, 61, 65, 66, 84, 96, 97, 107, 127, 235, 274, 288, 299
30BN82451B----[1] 8
31BN8251B----[1] 8
32Branaplam[1] Branaplam---[2] 3, 8
33Bupropion[1] Bupropion[3] D00817 ,
D07591 ,
D07938 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
34Calvan® 100 mg----[1] 8
35Cannabidiol[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[18] 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
36CBD----[12] 2, 6, 8, 13, 36, 46, 140, 144, 145, 156, 158, 206
37Cellavita HD Higher dose----[1] 8
38Cellavita HD Lower Dose----[1] 8
39Cellavita-HD----[1] 8
40Citalopram[1] Citalopram[2] D00822 ,
D07704 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
41CKD-504----[1] 8
42Coenzyme Q10[1] Ubidecarenone[1] D01065 --[12] 2, 5, 6, 8, 10, 18, 46, 57, 113, 193, 214, 215
43CoQ10----[3] 5, 6, 8
44Creatine[1] Creatine---[16] 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 113, 156, 201, 256
45Creatine Monohydrate[1] Creatine---[4] 2, 8, 113, 156
46CYSTAGON[1] Cysteamine[2] D03634 ,
D03635 		--[3] 8, 19, 299
47Cysteamine[1] Cysteamine[2] D03634 ,
D03635 		--[4] 8, 19, 21, 299
48Cysteamine Bitartrate[1] Cysteamine[2] D03634 ,
D03635 		--[4] 8, 19, 21, 299
49Deep Brain Stimulation----[5] 5, 6, 7, 8, 17
50Delta-9-tetrahydrocannabinol[1] Dronabinol[1] D00306 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[3] 8, 13, 36
51Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)[2] Cannabidiol,
Dronabinol		[2] D00306 ,
D10915 		[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 8
52Deutetrabenazine[1] Deutetrabenazine[1] D10701 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
53Deutetrabenazine Oral Tablet [Austedo][1] Deutetrabenazine[1] D10701 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
54Dextromethorphan[1] Dextromethorphan[3] D00848 ,
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
55Dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg)[2] Dextromethorphan,
Quinidine		[7] D00642 ,
D00643 ,
D00848 ,
D02272 ,
D03742 ,
D03744 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[1] 8
56Diagnostic Test: 11C-UCB-J PET-CT----[1] 8
57Diagnostic Test: 18F-FDG PET-MR[1] Fludeoxyglucose (18F)---[1] 8
58Digoxin[1] Digoxin[1] D00298 [4] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		[18] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 8, 46, 210
59Dimebon[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
60Dimebon (latrepirdine)[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
61Dimebon + Dextromethorphan[2] Dextromethorphan,
Latrepirdine		[4] D00848 ,
D03742 ,
D03744 ,
D09917 		[7] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
62Dimebon + Ketoconazole[2] Ketoconazole,
Latrepirdine		[2] D00351 ,
D09917 		[7] ACHE,
CYP17A1,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[28] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Metabolic pathways, Neuroactive ligand-receptor interaction, Nicotine addiction, Ovarian steroidogenesis, Pathways of neurodegeneration - multiple diseases, Prion disease, Prolactin signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Steroid hormone biosynthesis, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
63Dimebon + Omeprazole[2] Latrepirdine,
Omeprazole		[5] D00455 ,
D01207 ,
D05259 ,
D05261 ,
D09917 		[8] ACHE,
ATP4A,
ATP4B,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[26] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Dopaminergic synapse, Gastric acid secretion, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Metabolic pathways, Neuroactive ligand-receptor interaction, Nicotine addiction, Oxidative phosphorylation, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
64Dimebon alone[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
65Dimebon Dihydrochloride[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
66Dimebon IR[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
67Dimebon IR Tablet[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
68Dimebon MR1[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
69Dimebon MR2[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
70Dimebon MR3[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
71Dimebon MR4[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
72Dimebon Transdermal[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
73Divalproex----[1] 8
74DM----[2] 6, 8
75EGCG[1] Epigallocatechin gallate---[9] 6, 8, 13, 17, 28, 85, 113, 206, 299
76EPA----[6] 8, 46, 48, 49, 113, 301
77Epigallocatechin[1] Epigallocatechin---[5] 8, 13, 28, 85, 113
78Ethyl Icosapent[1] Icosapent[1] D08061 --[1] 8
79Ethyl-EPA[1] Icosapent ethyl[1] D01892 --[1] 8
80Ethyl-EPA (Miraxion™)[1] Icosapent ethyl[1] D01892 --[1] 8
81Ethyl-Icosapent[1] Icosapent[1] D08061 --[1] 8
82Fenofibrate[1] Fenofibrate[1] D00565 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[5] 8, 79, 93, 94, 265
83Graft intracerebral of foetal neurons----[1] 8
84GSK356278----[1] 8
85Haloperidol[1] Haloperidol[2] D00136 ,
D01898 		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
86Haloperidol 2Mg Tab[1] Haloperidol[2] D00136 ,
D01898 		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
87High doses of Thiamine y Biotin[2] Biotin,
Thiamine		[2] D00029 ,
D08580 		--[1] 8
88HYPERIUM[1] Rilmenidine[1] D08482 [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 8
89Icosapent[1] Icosapent[1] D08061 --[1] 8
90Idebenone[1] Idebenone[1] D01750 --[6] 6, 8, 13, 18, 113, 302
91ISIS 443139 10 mg----[1] 8
92ISIS 443139 120 mg----[1] 8
93ISIS 443139 30 mg----[1] 8
94ISIS 443139 60 mg----[1] 8
95ISIS 443139 90 mg----[1] 8
96Ketoconazole[1] Ketoconazole[1] D00351 [1] CYP17A1 💬[6] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[3] 8, 13, 75
97LAQUINIMOD[1] Laquinimod---[4] 8, 13, 49, 96
98Laquinimod capsules 0.5 mg[1] Laquinimod---[2] 8, 96
99Latrepirdine[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
100LAX-101[1] LAX-101---[1] 8
101Lithium[1] Lithium citrate[1] D04749 --[5] 2, 5, 6, 7, 8
102LMI070----[2] 3, 8
103LPM3770164 sustained release tablet[1] Manganese citrate---[1] 8
104LPM3770164 sustained release tablet simulant[1] Manganese citrate---[1] 8
105Melatonin[1] Melatonin[1] D08170 [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 90, 97, 144, 145, 149, 202
106Memantine[1] Memantine[2] D04905 ,
D08174 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 6, 8, 13, 49, 127, 205
107Metformin[1] Metformin[2] D00944 ,
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
108Minocycline[1] Minocycline[2] D00850 ,
D05045 		--[13] 2, 6, 8, 13, 46, 85, 90, 94, 162, 201, 206, 280, 299
109Moderate doses of Thiamine y Biotin[2] Biotin,
Thiamine		[2] D00029 ,
D08580 		--[1] 8
110N.a.----[10] 3, 6, 8, 13, 46, 96, 97, 240, 256, 271
111Neflamapimod[1] Neflamapimod[1] D10959 [4] MAPK11,
MAPK12,
MAPK13,
MAPK14 💬		[62] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬[1] 8
112Nilotinib[1] Nilotinib[1] D08953 [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬		[33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[5] 6, 8, 34, 51, 86
113Nilotinib 150 MG[1] Nilotinib[1] D08953 [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬		[33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[1] 8
114OLANZAPINE[1] Olanzapine[2] D00454 ,
D06623 		[11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
115Omeprazole[1] Omeprazole[4] D00455 ,
D01207 ,
D05259 ,
D05261 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
116OMS643762----[1] 8
117OSU6162 similar to (-)-OSU 6162----[2] 6, 8
118Other: 31-Phosphorus RMN Spectroscopy[1] Phosphorus---[1] 8
119PBF-999----[1] 8
120PBF-999 / 160 mg----[1] 8
121PBF-999 / 320 mg----[1] 8
122PBT2----[1] 8
123PF-02545920----[1] 8
124PHENYLBUTYRATE[1] Phenylbutyric acid---[12] 2, 3, 6, 8, 15, 93, 94, 244, 251, 297, 299, 338
125Phosphorus[1] Phosphorus---[2] 8, 238
126PL101----[1] 8
127Pridiopidine----[1] 8
128Pridopidina----[1] 8
129Pridopidine[1] Pridopidine[1] D09953 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8
130Pridopidine (90 mg)[1] Pridopidine[1] D09953 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
131PRIDOPIDINE HYDROCHLORIDE[1] Pridopidine[1] D09953 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
132Quinidine[1] Quinidine[4] D00642 ,
D00643 ,
D02272 ,
D08458 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13
133RAAV5-miHTT----[1] 8
134Ramelteon[1] Ramelteon[1] D02689 [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[3] 6, 8, 46
135Release[1] Manganese citrate---[12] 6, 8, 13, 46, 65, 78, 81, 96, 97, 206, 226, 299
136Resveratrol[1] Resveratrol---[6] 2, 8, 18, 89, 113, 299
137RG6042, formerly ISIS 443139, IONIS-HTTRx----[1] 8
138Rilmenidine[1] Rilmenidine[1] D08482 [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 8
139RILUZOLE[1] Riluzole[1] D00775 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
140Risperidone[1] Risperidone[1] D00426 [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[5] 8, 156, 179, 187, 206
141Risperidone 1Mg Tab[1] Risperidone[1] D00426 [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[1] 8
142Ro 723-4292/F02----[1] 8
143RO7234292----[1] 8
144RO7234292 (RG6042)----[1] 8
145Rolipram[1] Rolipram[1] D01783 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 8, 13
146RP 103----[2] 8, 19
147RP103----[2] 8, 19
148SAGE-718----[2] 6, 8
149SBT-020----[1] 8
150SD-809----[1] 8
151Selisistat[1] Selisistat---[1] 8
152SEN0014196----[1] 8
153SEN0014196 (High Dose)----[1] 8
154SEN0014196 (Low Dose)----[1] 8
155Sodium phenylbutyrate[1] Phenylbutyric acid---[4] 2, 3, 8, 251
156SOM3355 100mg BID----[1] 8
157SOM3355 200mg BID----[1] 8
158SRX246----[1] 8
159SS-20----[1] 8
160Tetrabenazine[1] Tetrabenazine[1] D08575 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
161Tetrabenazine withdrawal[1] Tetrabenazine[1] D08575 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
162Tetrahydrocannabinol[1] Dronabinol[1] D00306 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[4] 8, 13, 36, 298
163THC----[5] 8, 13, 36, 46, 96
164Thiamine[1] Thiamine[1] D08580 --[4] 8, 13, 93, 265
165Tiapridal----[1] 8
166Tominersen----[1] 8
167Triheptanoin[1] Triheptanoin[1] D11465 --[10] 2, 8, 65, 149, 156, 248, 256, 257, 317, 324
168Triheptanoin 1g/kg/day[1] Triheptanoin[1] D11465 --[1] 8
169Triheptanoin oil[1] Triheptanoin[1] D11465 --[1] 8
170TV-5600----[3] 8, 13, 96
171TV-7820----[1] 8
172Ubiquinol[1] Ubiquinol---[3] 6, 8, 17
173Ursodiol[1] Ursodeoxycholic acid[1] D00734 [1] NR1H4 💬[1] Bile secretion 💬[6] 8, 20, 93, 97, 234, 299
174UX007----[4] 8, 248, 256, 257
175Valbenazine[1] Valbenazine[1] D10675 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
176Vitamin B7[1] Biotin[1] D00029 --[1] 8
177VX-745----[1] 8
178VX15/2503----[2] 8, 13
179Warfarin[1] Warfarin[3] D00564 ,
D01280 ,
D08682 		[2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[13] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
180WVE-003----[1] 8
181WVE-120101----[1] 8
182WVE-120102----[1] 8
183Xenazine[1] Tetrabenazine[1] D08575 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
184Zoloft 50Mg Tablet----[1] 8