Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Biotin [1] Biotin[4] BIOTIN; Biotina; D-BIOTIN; Vitamin B7; --[5] 2, 8, 10, 13, 20
2 Haloperidol [1] Haloperidol[1] Haloperidol; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
3 Alprazolam [1] Alprazolam[1] Alprazolam; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 8, 75
4 Digoxin [1] Digoxin[1] Digoxin; [4] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		[18] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 8, 46, 210
5 Dronabinol [1] Dronabinol[4] Delta-9-tetrahydrocannabinol; DRONABINOL; Sativex; Tetrahydrocannabinol; [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[8] 2, 8, 13, 36, 46, 96, 271, 298
6 Ketoconazole [1] Ketoconazole[2] KETOCONAZOLE; NIZORAL; [1] CYP17A1 💬[6] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[3] 8, 13, 75
7 Risperidone [1] Risperidone[1] Risperidone; [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[5] 8, 156, 179, 187, 206
8 Olanzapine [1] Olanzapine[2] Olanzapine; Zyprexa; [11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
9 Omeprazole [1] Omeprazole[5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
10 Warfarin sodium [1] Warfarin[2] Warfarin; Warfarin Sodium; [2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[13] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
11 Fenofibrate [1] Fenofibrate[1] Fenofibrate; [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[5] 8, 79, 93, 94, 265
12 Quinidine gluconate [1] Quinidine[4] Nuedexta; Quinidina; Quinidine; Quinidine Sulfate; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13
13 Quinidine polygalacturonate [1] Quinidine[4] Nuedexta; Quinidina; Quinidine; Quinidine Sulfate; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13
14 Ursodiol [1] Ursodeoxycholic acid[4] UDCA; URSODEOXYCHOLIC ACID; Ursodiol; Ursofalk; [1] NR1H4 💬[1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299
15 Riluzole [1] Riluzole[2] Rilutek; Riluzole; [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
16 Amantadine hydrochloride [1] Amantadine[3] AMANTADINE; AMANTADINE HYDROCHLORIDE; GOCOVRI; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[4] 6, 8, 13, 127
17 Bupropion hydrochloride [1] Bupropion[2] Bupropion; Bupropion Hydrochloride; [2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
18 Citalopram hydrobromide [1] Citalopram[1] Citalopram; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
19 Dextromethorphan hydrobromide [1] Dextromethorphan[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
20 Minocycline hydrochloride [1] Minocycline[3] Minocycline; Minocycline hydrochloride; Minomycin; --[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299
21 Metformin hydrochloride [1] Metformin[5] Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine; [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
22 Ubidecarenone [1] Ubidecarenone[3] Coenzyme Q-10; Coenzyme Q10; CoQ10; --[13] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 193, 214, 215
23 Omeprazole sodium [1] Omeprazole[5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
24 Warfarin potassium [1] Warfarin[2] Warfarin; Warfarin Sodium; [2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[13] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
25 Idebenone [1] Idebenone[2] Idebenone; Raxone; --[6] 6, 8, 13, 18, 113, 302
26 Rolipram [1] Rolipram[1] Rolipram; [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 8, 13
27 Icosapent ethyl [1] Icosapent ethyl[2] Ethyl-EPA; Icosapent; --[2] 8, 296
28 Haloperidol decanoate [1] Haloperidol[1] Haloperidol; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
29 Quinidine sulfate [1] Quinidine[4] Nuedexta; Quinidina; Quinidine; Quinidine Sulfate; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13
30 Atomoxetine hydrochloride [1] Atomoxetine[2] Atomoxetine; Strattera; [1] SLC6A2 💬[1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17
31 Ramelteon [1] Ramelteon[2] Ramelteon; ROZEREM; [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[3] 6, 8, 46
32 Cysteamine [1] Cysteamine[8] 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; Cystagon; Cysteamine; Mercaptamina; Mercaptamine; PROCYSBI; --[4] 8, 19, 21, 299
33 Cysteamine hydrochloride [1] Cysteamine[8] 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; Cystagon; Cysteamine; Mercaptamina; Mercaptamine; PROCYSBI; --[4] 8, 19, 21, 299
34 Dextromethorphan [1] Dextromethorphan[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
35 Dextromethorphan polistirex [1] Dextromethorphan[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
36 Lithium citrate [1] Lithium citrate[2] Lithium; LITHIUM CITRATE; --[5] 2, 5, 6, 7, 8
37 Memantine hydrochloride [1] Memantine[3] EBIXA; MEMANTINE; MEMANTINE HYDROCHLORIDE; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 6, 8, 13, 49, 127, 205
38 Metformin [1] Metformin[5] Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine; [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
39 Minocycline [1] Minocycline[3] Minocycline; Minocycline hydrochloride; Minomycin; --[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299
40 Omeprazole magnesium [1] Omeprazole[5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
41 Omeprazole sodium injection [1] Omeprazole[5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
42 Olanzapine pamoate [1] Olanzapine[2] Olanzapine; Zyprexa; [11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
43 Amantadine [1] Amantadine[3] Amantadine; AMANTADINE HYDROCHLORIDE; GOCOVRI; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[4] 6, 8, 13, 127
44 Atomoxetine [1] Atomoxetine[2] Atomoxetine; Strattera; [1] SLC6A2 💬[1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17
45 Bupropion [1] Bupropion[2] Bupropion; Bupropion Hydrochloride; [2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
46 Citalopram [1] Citalopram[1] Citalopram; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
47 Bupropion hydrobromide [1] Bupropion[2] Bupropion; Bupropion Hydrochloride; [2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
48 Icosapent [1] Icosapent[2] Eicosapentaenoic acid; Icosapent; --[11] 8, 46, 48, 49, 96, 97, 113, 296, 297, 301, 338
49 Melatonin [1] Melatonin[2] Circadin; Melatonin; [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 90, 97, 144, 145, 149, 202
50 Memantine [1] Memantine[3] Ebixa; Memantine; MEMANTINE HYDROCHLORIDE; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 6, 8, 13, 49, 127, 205
51 Quinidine [1] Quinidine[4] Nuedexta; Quinidina; Quinidine; Quinidine Sulfate; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13
52 Rilmenidine [1] Rilmenidine[2] HYPERIUM; Rilmenidine; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 8
53 Tetrabenazine [1] Tetrabenazine[2] Tetrabenazine; Xenazine; [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
54 Thiamine [1] Thiamine[2] Thiamine; Vitamin B1; --[5] 8, 13, 93, 145, 265
55 Tiapride [1] Tiapride[0] [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
56 Warfarin [1] Warfarin[2] Warfarin; Warfarin Sodium; [2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[13] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
57 Nilotinib [1] Nilotinib[2] Nilotinib; Tasigna; [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬		[33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[5] 6, 8, 34, 51, 86
58 Latrepirdine [1] Latrepirdine[2] Dimebon; Latrepirdine; [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
59 Pridopidine [1] Pridopidine[1] Pridopidine; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8
60 Valbenazine [1] Valbenazine[1] Valbenazine; [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
61 Deutetrabenazine [1] Deutetrabenazine[1] Deutetrabenazine; [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
62 Cannabidiol [1] Cannabidiol[3] Cannabidiol; Epidyolex; SATIVEX; [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[19] 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
63 Neflamapimod [1] Neflamapimod[1] Neflamapimod; [4] MAPK11,
MAPK12,
MAPK13,
MAPK14 💬		[62] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬[1] 8
64 Triheptanoin [1] Triheptanoin[1] TRIHEPTANOIN; --[10] 2, 8, 65, 149, 156, 248, 256, 257, 317, 324