Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 2,2-bis(4-hydroxy-3-tert-butylphenyl)propane [0] ---[4] 19, 86, 276, 299
2 Abatacept [2] ABATACEPT; ORENCIA[1] D03203 [2] CD80,
CD86 💬		[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
3 Acetylcysteine [3] Acetylcysteine; Mucomyst; N-Acetylcysteine[1] D00221 --[20] 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
4 Adalimumab [6] Adalimumab; AMGEVITA; Hulio; HUMIRA; Hyrimoz; Imraldi[1] D02597 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
5 Adrabetadex [1] Adrabetadex---[1] 19
6 Afegostat [1] Afegostat[1] D09576 --[1] 19
7 Agalsidase alfa [5] AGALSIDASE ALFA; Agalsidase Alpha; Alpha-galactosidase A; Recombinant alpha-galactosidase A; REPLAGAL[1] D02784 [1] GLA 💬[6] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬[1] 19
8 Agalsidase beta [2] AGALSIDASE BETA; FABRAZYME[1] D03228 [1] GLA 💬[6] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬[1] 19
9 Alemtuzumab [4] Alemtuzumab; Campath; Lemtrada; MABCAMPATH[1] D02802 [1] CD52 💬-[22] 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326
10 Alendronic acid [3] Alendronate; Alendronate sodium; ALENDRONIC ACID[2] D00939 ,
D07119 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299
11 Alglucerase [1] Ceredase[1] D02810 [1] GBA 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
12 Ambroxol [1] Ambroxol[1] D07442 --[2] 6, 19
13 Amoxicillin [4] Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin[3] D00229 ,
D02925 ,
D07452 		--[9] 6, 19, 46, 63, 84, 96, 97, 222, 299
14 Anakinra [2] Anakinra; Kineret[1] D02934 [2] IL1R1,
IL1R2 💬		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[19] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
15 Angiotensin II [2] Angiotensin; Angiotensin II[2] D00150 ,
D02014 		[2] AGTR1,
AGTR2 💬		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 19, 46, 66, 86, 222, 224
16 Arimoclomol [1] ARIMOCLOMOL[1] D11374 --[3] 2, 15, 19
17 Ataluren [2] Ataluren; Translarna[1] D09323 --[6] 19, 113, 140, 246, 299, 329
18 Azathioprine [3] Azathioprine; Azatioprina; Imuran[2] D00238 ,
D03033 		--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
19 Barium [1] Barium---[3] 2, 19, 98
20 Betadex [1] Beta-cyclodextrin[1] D02401 --[1] 19
21 Busulfan [3] Busilvex; Busulfan; BUSULFANO[1] D00248 --[13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326
22 Calcium [2] Calcio; Calcium---[30] 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
23 Calcium carbonate [3] Calcio carbonato; Calcium; Calcium Carbonate[2] D00932 ,
D10802 		--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
24 Capsaicin [2] Capsaicin; Qutenza[1] D00250 [1] TRPV1 💬[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[5] 2, 6, 19, 86, 226
25 Carbonate ion [1] Carbonate---[12] 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299
26 Cerliponase alfa [2] Brineura; Cerliponase Alfa[1] D10813 [1] TPP1 💬[1] Lysosome 💬[1] 19
27 Cholecalciferol [5] Cholecalciferol; Colecalciferol; Multivitamin; Vitamin D; Vitamin D3[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[25] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
28 Cholesterol [1] Cholesterol[1] D00040 --[6] 19, 90, 160, 259, 261, 310
29 Clofarabine [1] Clofarabine[1] D03546 [3] POLA1,
POLA2,
RRM1 💬		[6] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[9] 19, 20, 40, 46, 49, 60, 96, 234, 326
30 Cyclophosphamide [6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; CYCLOPHOSPHAMIDE; Cyclophosphamidum; Cytoxan[2] D00287 ,
D07760 		--[45] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
31 Cyclosporine [10] CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
32 Cysteamine [8] 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; CYSTAGON; Cysteamine; Mercaptamina; Mercaptamine; PROCYSBI[2] D03634 ,
D03635 		--[4] 8, 19, 21, 299
33 Cysteine [2] Cysteine; Cysteine hydrochloride[2] D00026 ,
D02326 		--[11] 6, 13, 19, 34, 84, 85, 88, 90, 254, 296, 310
34 Eliglustat [2] Cerdelga; Eliglustat[1] D09893 [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[1] 19
35 Elosulfase alfa [3] Elosulfase alfa; Recombinant human N-acetylgalactosamine-6-sulfatase; RhGALNS[1] D10333 [1] GALNS 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19
36 ELX-02 [1] ELX-02---[2] 19, 299
37 Enalapril [2] Enalapril; Enalapril Maleate[2] D00621 ,
D07892 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222
38 Fludarabine [4] FLUDARA; FLUDARABINA; Fludarabine; Fludarabine Phosphate[2] D01907 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[19] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
39 Fluorescein [1] Fluorescein[2] D01261 ,
D02024 		--[3] 19, 22, 97
40 Gabapentin [4] GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN[1] D00332 [5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298
41 Galsulfase [2] GALSULFASE; Naglazyme[1] D06565 [1] ARSB 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19
42 Gamolenic acid [2] Gamma-Linolenic acid; Linolenic acid[1] D07213 --[3] 13, 19, 46
43 Gelatin [3] Gelatin; Gelatine; Sulfur Colloid[2] D00115 ,
D06892 		--[7] 19, 28, 62, 78, 97, 269, 299
44 Genistein [1] GENISTEIN[1] D11680 --[2] 19, 299
45 Hydroxypropyl betadex [1] 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN---[1] 19
46 Hydroxyurea [1] Hydroxyurea[1] D00341 [1] RRM2 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284
47 Idursulfase [4] Elaprase; Iduronate 2-sulfatase; IDURSULFASA; IDURSULFASE[1] D04499 [1] IDS 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19
48 Idursulfase beta [3] Hunterase; Iduronate 2-sulfatase; Idursulfase beta[1] D11025 [1] IDS 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19
49 Imidacloprid [0] ---[5] 19, 20, 125, 234, 326
50 Imiglucerase [3] CEREZYME; IMIGLUCERASA; IMIGLUCERASE[1] D03020 [1] GBA 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
51 Insulin-like growth factor II [0] ---[1] 19
52 Iohexol [2] Iohexol; OMNIPAQUE[1] D01817 --[3] 19, 67, 222
53 Laronidase [2] Aldurazyme; LARONIDASE[1] D04670 [1] IDUA 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[2] 19, 256
54 Ledipasvir [2] Harvoni; Ledipasvir[1] D10442 --[2] 19, 254
55 Lenograstim [2] G-CSF; LENOGRASTIM[1] D03247 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65
56 Leucine [2] L-leucine; Leucine[1] D00030 --[11] 5, 6, 7, 19, 65, 96, 97, 127, 283, 284, 299
57 Leucovorin [2] Folinic acid; Leucovorin[3] D01211 ,
D07986 ,
D07987 		--[4] 19, 46, 107, 320
58 Levothyroxine [3] Levothyroxine; Thyroid; Thyroxine[2] D01010 ,
D08125 		[2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[5] 19, 49, 78, 80, 222
59 Lisinopril [2] Lisinopril; Zestril[2] D00362 ,
D08131 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222
60 Lithium carbonate [2] Lithium; LITHIUM CARBONATE[1] D00801 --[6] 2, 13, 17, 18, 19, 127
61 Losartan [3] Cozaar; Losartan; Losartan Potassium[2] D00357 ,
D08146 		[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
62 Lucerastat [1] Lucerastat[1] D11439 [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[1] 19
63 Lysine [1] Lysine[1] D02304 --[5] 13, 19, 97, 228, 299
64 Medical Cannabis [3] Cannabis; Marijuana; Medical Cannabis---[9] 2, 6, 13, 19, 46, 90, 96, 97, 271
65 Melphalan [3] Alkeran; Melphalan; Melphalan Hydrochloride[1] D00369 --[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299
66 Methamidophos [1] MONITOR---[20] 2, 11, 13, 19, 28, 46, 49, 58, 65, 70, 81, 85, 86, 98, 113, 118, 129, 298, 299, 300
67 Methotrexate [6] Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; Metotrexato; Méthotrexate[2] D00142 ,
D02115 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
68 Methylprednisolone [4] Medrol; Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE[6] D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
69 Migalastat [3] 1-Deoxygalactonojirimycin; Galafold; MIGALASTAT[1] D10359 --[1] 19
70 Miglustat [2] MIGLUSTAT; ZAVESCA[1] D05032 [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[3] 19, 256, 299
71 Mucopolysaccharide polysulphate [0] ---[1] 19
72 Mycophenolate mofetil [3] CellCept; Mycophenolate mofetil; Mycophenolate mofetil TEVA[3] D00752 ,
D05094 ,
D05095 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
73 Mycophenolic acid [5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
74 Odiparcil [1] Odiparcil---[1] 19
75 Olenasufligene relduparvovec [1] OLENASUFLIGENE RELDUPARVOVEC---[1] 19
76 Olipudase alfa [1] Olipudase alfa[1] D10820 [1] SMPD1 💬[5] Lysosome, Metabolic pathways, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬[1] 19
77 Oxygen [3] Medical air; Nitrogen; Oxygen[1] D00003 --[20] 6, 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 168, 193, 226, 271, 294, 299, 330
78 Pabinafusp alfa [1] Pabinafusp alfa[1] D11812 [2] IDS,
TFRC 💬		[8] Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome, Metabolic pathways, Phagosome 💬[1] 19
79 Paricalcitol [1] Paricalcitol[1] D00930 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[4] 19, 66, 218, 238
80 Pegunigalsidase alfa [1] PEGUNIGALSIDASE ALFA[1] D11685 --[1] 19
81 Pentosan polysulfate [1] Pentosan polysulfate[1] D05428 --[3] 19, 26, 226
82 Plerixafor [2] Mozobil; PLERIXAFOR[1] D08971 [1] CXCR4 💬[12] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral protein interaction with cytokine and cytokine receptor 💬[6] 19, 20, 51, 65, 285, 299
83 Prednisone [3] Prednisona; PREDNISONE; RAYOS[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
84 Pyrimethamine [2] Daraprim; Pyrimethamine[1] D00488 --[11] 2, 4, 6, 13, 19, 46, 51, 65, 96, 97, 265
85 Quinapril [1] Accuretic[2] D00459 ,
D03752 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 19
86 Rimiducid [1] Rimiducid[1] D11195 [1] CASP9 💬[35] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[6] 19, 60, 65, 284, 285, 326
87 Rituximab [6] MABTHERA; Rituxan; Rituximab; Rixathon; Ruxience; TRUXIMA[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[49] 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
88 Sebelipase alfa [4] KANUMA; SBC-102; Sebelipasa Alfa; Sebelipase Alfa[1] D10377 [1] LIPA 💬[3] Cholesterol metabolism, Lysosome, Steroid biosynthesis 💬[1] 19
89 Sirolimus [3] RAPAMUNE; Rapamycin; Sirolimus[1] D00753 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[41] 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
90 SOBI-003 [0] ---[1] 19
91 Sofosbuvir [2] Harvoni; Sofosbuvir[1] D10366 --[2] 19, 254
92 Somatotropin [17] Genotropin; Growth hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; Somatropin; SOMATROPINA; Zomacton[1] D02691 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[23] 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
93 Taliglucerase alfa [3] Elelyso; PrGCD; TALIGLUCERASE ALFA[1] D09675 [1] GBA 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
94 Thiotepa [1] THIOTEPA[1] D00583 --[12] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285
95 Tilactase [1] Beta-Galactosidase[1] D03348 --[1] 19
96 Treosulfan [2] OVASTAT; Treosulfan[1] D07253 --[6] 13, 19, 62, 65, 283, 286
97 Tropicamide [1] Tropicamide[1] D00397 [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 19
98 Velaglucerase alfa [3] GA-GCB; VELAGLUCERASE ALFA; VPRIV[1] D09029 [1] GBA 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
99 Velmanase alfa [3] LAMAZYM; RhLAMAN; VELMANASE ALFA[1] D11024 [1] MAN2B1 💬[2] Lysosome, Other glycan degradation 💬[1] 19
100 Venglustat [2] GENZ-682452; Venglustat[1] D11633 [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[3] 6, 19, 67
101 Vestronidase alfa [3] Mepsevii; Recombinant human beta-glucuronidase; Vestronidase alfa[1] D11004 [1] GUSB 💬[8] Ascorbate and aldarate metabolism, Biosynthesis of cofactors, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome, Metabolic pathways, Pentose and glucuronate interconversions, Porphyrin metabolism 💬[1] 19
102 Vitamin D [3] Calciferol; Cod liver oil; Vitamin D---[24] 3, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299
103 Vorinostat [1] Vorinostat[1] D06320 [11] HDAC1,
HDAC10,
HDAC11,
HDAC2,
HDAC3,
HDAC4,
HDAC5,
HDAC6,
HDAC7,
HDAC8,
HDAC9 💬		[17] Alcoholism, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Cell cycle, Chronic myeloid leukemia, Epstein-Barr virus infection, Human papillomavirus infection, Huntington disease, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, Notch signaling pathway, Pathways in cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis 💬[3] 19, 75, 96
104 Warfarin [2] Warfarin; Warfarin Sodium[3] D00564 ,
D01280 ,
D08682 		[2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[13] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
105 Water [9] AVONEX; ENBREL; Glucagon; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION[1] D00001 --[23] 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299