Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen [5] Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Acetylsalicylic acid [2] Acetylsalicylic Acid; Aspirin[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251
3 Alpha-1-proteinase inhibitor [6] Alpha 1-Antitrypsin; Alpha 1-Proteinase Inhibitor; ALPHA-1-ANTITRYPSIN; Alpha1-proteinase Inhibitor; Glassia; Prolastin-C---[3] 231, 298, 299
4 Alvelestat [1] ALVELESTAT---[1] 231
5 Carbamazepine [1] Carbamazepine[1] D00252 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[2] 13, 231
6 Fentanyl [1] Fentanyl[2] D00320 ,
D01399 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[4] 46, 70, 215, 231
7 Hyaluronic acid [3] Hyaluronan; Hyaluronate; Hyaluronic Acid[1] D08043 --[7] 46, 53, 70, 97, 226, 231, 299
8 Interleukin-1 alpha, human recombinant [1] None---[13] 6, 46, 51, 65, 84, 85, 96, 97, 140, 161, 231, 271, 299
9 Lidocaine [4] Aloe; Lidocaine; Lignocaine; Xylocaine[3] D00358 ,
D02086 ,
D08127 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
10 Lorazepam [1] Lorazepam[1] D00365 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 36, 231
11 Midazolam [2] Midazolam; Midazolam injection[3] D00550 ,
D00696 ,
D05028 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
12 Ondansetron [1] Ondansetron[2] D00456 ,
D00678 		[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[4] 6, 97, 107, 231
13 Oxycodone [3] Oxycodone; OXYCODONE HYDROCHLORIDE; Oxycodone/Acetaminophen[3] D03783 ,
D05312 ,
D05462 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298
14 Phenylbutyric acid [4] 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium phenylbutyrate---[14] 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338
15 Salbutamol [3] Albuterol; Salbutamol; Ventolin[1] D02147 [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[14] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299
16 Tretinoin [5] ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID[1] D00094 [3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[6] 2, 62, 63, 75, 94, 231