Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abacavir [4] Abacavir; Abacavir sulfate; Triumeq; Ziagen[2] D00891 ,
D07057 		--[4] 2, 135, 265, 325
2 Acetate [1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
3 Acetylcarnitine [2] Acetyl-L-carnitine; Acetylcarnitine---[3] 2, 265, 298
4 Acipimox [1] Acipimox[1] D07190 --[2] 78, 265
5 Amprenavir [1] Amprenavir[1] D00894 --[1] 265
6 ANX-510 [0] ---[3] 6, 265, 288
7 Aramchol [1] Aramchol---[1] 265
8 Atazanavir [2] Atazanavir; Reyataz[2] D01276 ,
D07471 		--[1] 265
9 Atorvastatin [3] Atorvastatin; Atorvastatin Calcium; Lipitor[3] D00258 ,
D00887 ,
D07474 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
10 Baricitinib [2] Baricitinib; Olumiant[1] D10308 [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
11 Berberine [1] Berberine---[2] 97, 265
12 Caffeine [1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 2, 6, 13, 21, 46, 78, 96, 97, 265
13 Calcium [2] Calcio; Calcium---[30] 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
14 Cholic Acid [1] Cholic Acid[1] D10699 [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 234, 265, 310
15 Cyclophosphamide [6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan[2] D00287 ,
D07760 		--[45] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
16 Didanosine [1] Didanosine[1] D00296 --[2] 25, 265
17 Diosmin [1] DIOSMIN[1] D07858 --[1] 265
18 Dolutegravir [2] Dolutegravir; Triumeq[1] D10066 --[2] 2, 265
19 Doravirine [1] Doravirine[1] D10624 --[1] 265
20 Efavirenz [2] Efavirenz; SUSTIVA[1] D00896 --[1] 265
21 Emtricitabine [2] Emtricitabine; TRUVADA[1] D01199 --[4] 25, 93, 265, 325
22 Enfuvirtide [1] Enfuvirtide[1] D02499 --[2] 25, 265
23 Fenofibrate [1] Fenofibrate[1] D00565 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[5] 8, 79, 93, 94, 265
24 Gemcabene [1] Gemcabene---[2] 79, 265
25 Glycerin [3] Bee venom; Glycerine; Glycerol[1] D00028 --[6] 6, 13, 79, 265, 316, 317
26 Indinavir [1] Indinavir[3] D00897 ,
D02861 ,
D03833 		--[1] 265
27 L-Lactic acid [2] L-Lactic acid; Lactic acid---[1] 265
28 Lactic acid [1] Lactic acid[1] D00111 --[2] 265, 299
29 Lamivudine [4] COMBIVIR; Epivir; Lamivudine; Triumeq[1] D00353 --[7] 2, 26, 42, 46, 135, 265, 325
30 Leptin [1] Leptin---[2] 6, 265
31 Levocarnitine [4] Carnitine; L-Carnitine; Levocarnitine; Xyzal[3] D02030 ,
D02176 ,
D04713 		--[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
32 Lopinavir [2] Kaletra; Lopinavir[1] D01425 --[2] 93, 265
33 Mecasermin [3] Increlex; MECASERMIN; MECASERMINA[2] D03297 ,
D04870 		[2] GHR,
IGF1R 💬		[33] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[6] 65, 78, 96, 168, 265, 299
34 Metformin [5] METFORMIN; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine[2] D00944 ,
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
35 Metreleptin [3] METRELEPTIN; Myalept; R-metHuLeptin[1] D05014 [1] LEPR 💬[6] AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬[1] 265
36 Nelfinavir [1] Nelfinavir[2] D00899 ,
D08259 		--[3] 49, 265, 331
37 Nevirapine [1] Nevirapine[1] D00435 --[1] 265
38 Niacin [2] Niacin; Nicotinic acid[1] D00049 --[4] 6, 78, 79, 265
39 Obeticholic acid [4] 6-ECDCA; 6-ethylchenodeoxycholic acid; OBETICHOLIC ACID; Ocaliva[1] D09360 [1] NR1H4 💬[1] Bile secretion 💬[3] 93, 265, 296
40 Pioglitazone [1] PIOGLITAZONE[2] D00945 ,
D08378 		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
41 Poly(lactic acid) [1] POLY-L-LACTIC ACID---[1] 265
42 Pravastatin [2] Pravastatin; Pravastatin sodium[2] D00893 ,
D08410 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
43 Pyrimethamine [2] Daraprim; Pyrimethamine[1] D00488 --[11] 2, 4, 6, 13, 19, 46, 51, 65, 96, 97, 265
44 Raltegravir [2] ISENTRESS; Raltegravir[1] D06676 --[4] 13, 26, 93, 265
45 Riboflavin [2] Riboflavin; Vitamin B2[3] D00050 ,
D01622 ,
D01913 		--[8] 13, 38, 46, 96, 97, 162, 168, 265
46 Ritonavir [2] Norvir; Ritonavir[1] D00427 --[3] 2, 86, 265
47 Rosiglitazone [2] Rosiglitazone; Rosiglitazone maleate[2] D00596 ,
D08491 		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265
48 Saquinavir [1] Saquinavir[2] D00429 ,
D01160 		--[2] 86, 265
49 Setmelanotide [1] Setmelanotide[1] D11927 [1] MC4R 💬[1] Neuroactive ligand-receptor interaction 💬[2] 202, 265
50 Simvastatin [3] SIMVASTATIN; Simvastatina; Simvastatine[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
51 Somatotropin [17] Genotropin; Growth Hormone; Human Growth Hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; Somatropin; SOMATROPINA; Zomacton[1] D02691 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[23] 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
52 Stavudine [1] Stavudine[1] D00445 --[1] 265
53 Sulfate ion [1] Sulfate---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 218, 222, 226, 265, 296, 297, 299
54 Tenofovir [1] Tenofovir[1] D06074 --[6] 2, 13, 25, 93, 265, 325
55 Tenofovir disoproxil [4] Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA[1] D01982 --[2] 93, 265
56 Tesamorelin [2] GHRH; Tesamorelin[1] D06655 [1] GHRHR 💬[2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[2] 78, 265
57 Testosterone [1] Testosterone[6] D00075 ,
D00957 ,
D00958 ,
D00959 ,
D06085 ,
D06087 		[1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265
58 Thiamine [2] Thiamine; Vitamin B1[1] D08580 --[5] 8, 13, 93, 145, 265
59 Tipranavir [1] Tipranavir[2] D03843 ,
D08605 		--[1] 265
60 Volanesorsen [1] Volanesorsen[1] D11648 [1] APOC3 💬[2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265
61 Zidovudine [3] COMBIVIR; Retrovir; Zidovudine[1] D00413 --[7] 25, 26, 94, 135, 265, 325, 331