Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetate [1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
2 Acipimox [1] Acipimox[1] D07190 --[2] 78, 265
3 Albumin human [5] Albumin; Human albumin; Human serum albumin; Optison; Serum albumin[2] D02792 ,
D05424 		--[3] 2, 78, 96
4 Amitriptyline [3] Amitriptylin; Amitriptyline; Amitriptyline hydrochloride[2] D00809 ,
D07448 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 78, 97, 226, 299
5 Anastrozole [2] ANASTROZOLE; Arimidex[1] D00960 [1] CYP19A1 💬[3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[3] 78, 86, 193
6 Arginine [6] Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene[1] D02982 --[12] 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299
7 ARX201 [1] ARX201---[1] 78
8 Caffeine [1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 2, 6, 13, 21, 46, 78, 96, 97, 265
9 Chloride ion [1] Chloride---[29] 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 271, 288, 296, 297, 299, 338
10 Clonidine [4] Clonidin; Clonidina; Clonidine; CLONIDINE HYDROCHLORIDE[2] D00281 ,
D00604 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[4] 6, 65, 70, 78
11 Corticotropin [5] ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[15] 2, 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222
12 Dextromethorphan [4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta[3] D00848 ,
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
13 Diclofenac [3] Diclofenac; Diclofenac sodium; Diclofenac SR[3] D00903 ,
D00904 ,
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271
14 Donepezil [3] Aricept; Donepezil; Donepezil hydrochloride[2] D00670 ,
D07869 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
15 Escherichia coli [1] Escherichia coli---[2] 53, 78
16 Exenatide [3] Bydureon; Byetta; Exenatide[1] D04121 [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233
17 Fluoxetine [5] Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC[2] D00326 ,
D00823 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[6] 13, 17, 78, 86, 179, 206
18 Gelatin [3] Gelatin; Gelatine; Sulfur Colloid[2] D00115 ,
D06892 		--[7] 19, 28, 62, 78, 97, 269, 299
19 Glucagon [1] Glucagon[2] D00116 ,
D02118 		[1] GCGR 💬[2] Glucagon signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 78
20 Hydrocortisone [6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] D00088 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[11] 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
21 Lenomorelin [1] Ghrelin---[6] 6, 78, 193, 201, 202, 299
22 Levothyroxine [3] Levothyroxine; Thyroid; Thyroxine[2] D01010 ,
D08125 		[2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[5] 19, 49, 78, 80, 222
23 Liothyronine [4] Liothyronine; Liothyronine sodium; Thyroid; Triiodothyronine[2] D01011 ,
D08128 		[2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[4] 13, 78, 210, 212
24 Lonapegsomatropin [1] LONAPEGSOMATROPIN[1] D11486 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78
25 Macimorelin [2] Macimorelin; Macrilen[1] D10563 [1] GHSR 💬[3] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 78
26 Manganese citrate [1] Release---[12] 6, 8, 13, 46, 65, 78, 81, 96, 97, 206, 226, 299
27 Mecasermin [3] Increlex; Mecasermin; MECASERMINA[2] D03297 ,
D04870 		[2] GHR,
IGF1R 💬		[33] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[6] 65, 78, 96, 168, 265, 299
28 Methyl salicylate 2-ethylbutyrate [1] TheraDerm---[1] 78
29 Niacin [2] Niacin; Nicotinic acid[1] D00049 --[4] 6, 78, 79, 265
30 Pegvisomant [1] Pegvisomant[1] D05394 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78
31 Phosphate ion [1] Phosphate---[33] 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
32 Pioglitazone [1] Pioglitazone[2] D00945 ,
D08378 		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
33 Polyethylene glycol [4] Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350[1] D03370 --[14] 6, 13, 41, 46, 65, 78, 96, 97, 140, 144, 235, 240, 276, 299
34 Sodium chloride [6] Lactated Ringers; Natriumchlorid; REBIF; SALINE; Sodium chloride; SPORANOX[1] D02056 --[21] 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 168, 193, 227, 228, 271, 288, 299
35 Somapacitan [1] SOMAPACITAN[1] D11194 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78
36 Somatorelin [2] GHRH; Somatorelin[1] D08523 [1] GHRHR 💬[2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[2] 13, 78
37 Somatostatin [1] Somatostatin[1] D07431 [5] SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬		[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[2] 67, 78
38 Somatotropin [17] Genotropin; Growth hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; Recombinant human growth hormone; RhGH; SAIZEN; Somatotropin; SOMATROPIN; SOMATROPINA; Zomacton[1] D02691 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[23] 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
39 Somatrogon [1] Somatrogon[1] D10990 --[1] 78
40 Somatropin pegol [1] NNC126-0083---[1] 78
41 Somavaratan [1] Somavaratan[1] D11193 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78
42 Strontium ranelate [1] Strontium ranelate[1] D08468 --[1] 78
43 Tesamorelin [2] GHRH; Tesamorelin[1] D06655 [1] GHRHR 💬[2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[2] 78, 265
44 Testosterone [1] Testosterone[6] D00075 ,
D00957 ,
D00958 ,
D00959 ,
D06085 ,
D06087 		[1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265
45 Tetracosactide [4] Cosyntropin; SYNACTHEN DEPOT; Tetracosactide; Tetracosactrin[1] D00284 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 78, 83, 113, 145, 222
46 Thyroid, porcine [1] Thyroid---[1] 78
47 Tiratricol [1] TIRATRICOL[1] D07214 [2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[2] 78, 139
48 Tramadol [2] Tramadol; Ultracet[2] D01355 ,
D08623 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271
49 Water [9] AVONEX; ENBREL; Glucagon; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION[1] D00001 --[23] 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299