Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 L-Cysteine [1] Cysteine[2] Cysteine; Cysteine hydrochloride; --[11] 6, 13, 19, 34, 84, 85, 88, 90, 254, 296, 310
2 Leucine [1] Leucine[2] L-leucine; Leucine; --[11] 5, 6, 7, 19, 65, 96, 97, 127, 283, 284, 299
3 Levodopa [1] Levodopa[8] DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[8] 2, 4, 6, 17, 90, 140, 164, 201
4 l-Menthol -[0] ---
5 Lactic acid [1] Lactic acid[1] Lactic acid; --[2] 265, 299
6 Lincomycin -[0] ---
7 Lactulose [1] Lactulose[1] Lactulose; --[3] 13, 96, 291
8 Lamivudine [1] Lamivudine[4] COMBIVIR; Epivir; Lamivudine; Triumeq; --[7] 2, 26, 42, 46, 135, 265, 325
9 Lamotrigine [1] Lamotrigine[2] Lamictal; Lamotrigine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 13, 34, 38, 114, 144
10 Lansoprazole [1] Lansoprazole[1] LANSOPRAZOLE; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[7] 63, 71, 85, 98, 166, 222, 299
11 Latanoprost -[0] ---
12 Losartan potassium [1] Losartan[3] Cozaar; Losartan; LOSARTAN POTASSIUM; [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
13 Lidocaine [1] Lidocaine[4] Aloe; Lidocaine; Lignocaine; Xylocaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
14 Lovastatin [1] Lovastatin[1] Lovastatin; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
15 Lindane -[0] ---
16 Liotrix -[0] ---
17 Lisinopril [1] Lisinopril[2] Lisinopril; Zestril; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222
18 Lomustine -[0] ---
19 Loratadine [1] Loratadine[2] Loratadina; Loratadine; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 46, 89, 98
20 Lorazepam [1] Lorazepam[1] Lorazepam; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 36, 231
21 Lypressin -[0] ---
22 Levofloxacin [1] Levofloxacin[2] Levaquin; Levofloxacin; --[5] 46, 53, 84, 85, 299
23 Labetalol hydrochloride -[0] ---
24 Levetiracetam [1] Levetiracetam[2] KEPPRA; Levetiracetam; [1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307
25 Loperamide hydrochloride [1] Loperamide[2] LOPERAMIDE; Loperamide hydrochloride; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97
26 Leflunomide [1] Leflunomide[3] ARAVA; Leflunomide; Leflunomidum; [1] DHODH 💬[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
27 Levamisole hydrochloride [1] Levamisole[1] Levamisole; --[3] 60, 61, 62
28 Loxapine succinate -[0] ---
29 Lithium carbonate [1] Lithium carbonate[2] Lithium; LITHIUM CARBONATE; --[6] 2, 13, 17, 18, 19, 127
30 Levorphanol tartrate -[0] ---
31 Lomefloxacin hydrochloride -[0] ---
32 Loracarbef -[0] ---
33 Linezolid [1] Linezolid[1] LINEZOLID; --[1] 299
34 Levonorgestrel [1] Levonorgestrel[1] LEVONORGESTREL; [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13
35 Letrozole [1] Letrozole[1] Letrozole; [1] CYP19A1 💬[3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[2] 81, 89
36 Leuprolide acetate [1] Leuprolide[2] Leuprolide; Leuprorelin; [1] GNRHR 💬[2] GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬[5] 1, 2, 3, 51, 76
37 Levothyroxine sodium [1] Levothyroxine[3] Levothyroxine; Thyroid; Thyroxine; [2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[5] 19, 49, 78, 80, 222
38 Liothyronine sodium [1] Liothyronine[4] Liothyronine; Liothyronine sodium; Thyroid; Triiodothyronine; [2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[4] 13, 78, 210, 212
39 Levobunolol hydrochloride -[0] ---
40 Lafutidine -[0] ---
41 Leucovorin calcium [1] Leucovorin[2] Folinic acid; Leucovorin; --[4] 19, 46, 107, 320
42 Levobupivacaine hydrochloride [1] Levobupivacaine[2] Bupivacaine; Levobupivacaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 46
43 Lopinavir [1] Lopinavir[2] Kaletra; Lopinavir; --[2] 93, 265
44 Lisuride maleate [1] Lisuride[1] Lisuride; [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 86
45 Lynestrenol -[0] ---
46 Lormetazepam -[0] ---
47 Lime -[0] ---
48 Loteprednol etabonate -[0] ---
49 Lentinan -[0] ---
50 Levocabastine hydrochloride -[0] ---
51 Lercanidipine hydrochloride -[0] ---
52 Lornoxicam -[0] ---
53 Lanatoside C -[0] ---
54 Luliconazole -[0] ---
55 Levocarnitine chloride [1] Levocarnitine[4] Carnitine; L-Carnitine; Levocarnitine; Xyzal; --[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
56 Lidocaine hydrochloride [1] Lidocaine[4] Aloe; Lidocaine; Lignocaine; Xylocaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
57 l-Isoprenaline hydrochloride -[0] ---
58 Levocarnitine [1] Levocarnitine[4] Carnitine; L-Carnitine; Levocarnitine; Xyzal; --[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
59 Levallorphan tartrate -[0] ---
60 Levmetamfetamine -[0] ---
61 Lysine [1] Lysine[1] Lysine; --[5] 13, 19, 97, 228, 299
62 Lomefloxacin -[0] ---
63 Loxapine -[0] ---
64 Lobeline -[0] ---
65 Levonordefrin -[0] ---
66 Lomefloxacin mesylate -[0] ---
67 Limaprost [1] Limaprost[1] Limaprost; [1] PTGER1 💬[4] Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer 💬[1] 70
68 Lactose [1] Lactose[1] Lactose; --[6] 2, 6, 13, 97, 228, 310
69 Lenograstim [1] Lenograstim[2] G-CSF; Lenograstim; [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65
70 Lactase [1] Tilactase[1] Beta-Galactosidase; --[1] 19
71 Lumiracoxib [1] Lumiracoxib[1] Lumiracoxib; [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
72 Lidorestat -[0] ---
73 Lumefantrine -[0] ---
74 Lapatinib ditosylate [1] Lapatinib[1] Lapatinib; [2] EGFR,
ERBB2 💬		[50] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction 💬[3] 34, 74, 75
75 Lactomin [1] Lactobacillus acidophilus[2] Acidophilus; Lactobacillus; --[1] 97
76 Lactobacillus casei [1] Lactobacillus casei[2] Fusion; Lactobacillus casei; --[10] 6, 11, 13, 46, 49, 69, 70, 97, 271, 296
77 Lacidipine -[0] ---
78 Lanimostim -[0] ---
79 Lanolin -[0] ---
80 Lanolin alcohols -[0] ---
81 Lanolin, modified -[0] ---
82 Lanoteplase -[0] ---
83 Lanthanum carbonate -[0] ---
84 Laronidase [1] Laronidase[2] Aldurazyme; Laronidase; [1] IDUA 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[2] 19, 256
85 Lasalocid -[0] ---
86 Lecithin [2] Lecithin,
Phosphatidyl serine		[1] Phosphatidylcholine; --[5] 6, 46, 90, 97, 97
87 Lenalidomide [1] Lenalidomide[2] Lenalidomide; REVLIMID; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 16, 26, 28, 34, 49, 284, 300, 331
88 Leridistim -[0] ---
89 Lestaurtinib -[0] ---
90 Levocarnitine propionate hydrochloride [1] Levocarnitine[4] Carnitine; L-Carnitine; Levocarnitine; Xyzal; --[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
91 Levomethadyl acetate -[0] ---
92 Levosimendan [1] Levosimendan[1] LEVOSIMENDAN; [2] PDE3A,
PDE3B 💬		[11] Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 2
93 Liatermin [1] Liatermin[2] Liatermin; R-metHuGDNF; --[1] 6
94 Lidoflazine -[0] ---
95 Lifibrol -[0] ---
96 Linopirdine -[0] ---
97 Lisofylline -[0] ---
98 Lithium citrate [1] Lithium citrate[2] Lithium; LITHIUM CITRATE; --[5] 2, 5, 6, 7, 8
99 Lithium hydroxide -[0] ---
100 Lixivaptan [1] Lixivaptan[1] Lixivaptan; [1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
101 Lobucavir -[0] ---
102 Lofexidine hydrochloride -[0] ---
103 Lonafarnib [1] Lonafarnib[1] Lonafarnib; [2] FNTA,
FNTB 💬		[1] Terpenoid backbone biosynthesis 💬[2] 113, 333
104 Lortalamine -[0] ---
105 Lubiprostone [1] Lubiprostone[1] Lubiprostone; [1] CLCN2 💬[1] Mineral absorption 💬[4] 6, 13, 290, 299
106 Lucinactant [1] Lucinactant[1] Lucinactant; --[1] 299
107 Lutropin alfa -[0] ---
108 Lyapolate sodium -[0] ---
109 Liraglutide [1] Liraglutide[2] Liraglutide; Saxenda; [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 6, 75, 193
110 Lumiliximab -[0] ---
111 Light anhydrous silicic acid -[0] ---
112 Lexatumumab -[0] ---
113 Lepirudin -[0] ---
114 Lymecycline -[0] ---
115 Loperamide oxide [1] Loperamide[2] LOPERAMIDE; Loperamide hydrochloride; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97
116 Linsidomine -[0] ---
117 Lonidamine -[0] ---
118 Lonazolac -[0] ---
119 Lacosamide [1] Lacosamide[1] Lacosamide; [2] SCN3A,
SCN9A 💬		[1] Taste transduction 💬[3] 2, 46, 149
120 Levosulpiride -[0] ---
121 Loprazolam -[0] ---
122 Letosteine -[0] ---
123 Levocetirizine [1] Levocetirizine[1] Levocetirizina; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 61
124 L-Citrulline [1] Citrulline[1] Citrulline; --[2] 86, 113
125 Lorcainide -[0] ---
126 Labetalol -[0] ---
127 Lapatinib [1] Lapatinib[1] Lapatinib; [2] EGFR,
ERBB2 💬		[50] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction 💬[3] 34, 74, 75
128 Latamoxef -[0] ---
129 Lercanidipine -[0] ---
130 Levamisole [1] Levamisole[1] Levamisole; --[3] 60, 61, 62
131 Levobunolol -[0] ---
132 Levobupivacaine [1] Levobupivacaine[2] Bupivacaine; Levobupivacaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 46
133 Levocabastine -[0] ---
134 Levodropropizine -[0] ---
135 Levofloxacin [1] Levofloxacin[2] Levaquin; Levofloxacin; --[5] 46, 53, 84, 85, 299
136 Levomethadone -[0] ---
137 Levorphanol -[0] ---
138 Levosalbutamol [1] Levosalbutamol[2] R-salbutamol; Salbutamol; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 49
139 Levothyroxine [1] Levothyroxine[3] Levothyroxine; Thyroid; Thyroxine; [2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[5] 19, 49, 78, 80, 222
140 Lidocaine hydrochloride monohydrate [1] Lidocaine[4] Aloe; Lidocaine; Lignocaine; Xylocaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
141 Liothyronine [1] Liothyronine[4] Liothyronine; Liothyronine sodium; Thyroid; Triiodothyronine; [2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[4] 13, 78, 210, 212
142 Lisdexamfetamine [1] Lisdexamfetamine[1] Lisdexamfetamine; [2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 13
143 Lisinopril [1] Lisinopril[2] Lisinopril; Zestril; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222
144 Lisuride [1] Lisuride[1] Lisuride; [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 86
145 Lithium -[0] ---
146 Lodoxamide -[0] ---
147 Lofepramine -[0] ---
148 Lofexidine -[0] ---
149 Loracarbef -[0] ---
150 Loperamide [1] Loperamide[2] Loperamide; Loperamide hydrochloride; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97
151 Losartan [1] Losartan[3] Cozaar; Losartan; Losartan Potassium; [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
152 Loteprednol -[0] ---
153 Loxoprofen [1] Loxoprofen[1] Loxoprofen; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 46, 271
154 Lufenuron -[0] ---
155 Luprostiol -[0] ---
156 Lysozyme -[0] ---
157 Lactitol -[0] ---
158 Labetuzumab -[0] ---
159 Labradimil -[0] ---
160 Laromustine -[0] ---
161 Laropiprant -[0] ---
162 Lucatumumab -[0] ---
163 Larazotide -[0] ---
164 Levomefolic acid [1] Levomefolic acid[1] L-methylfolate; --[1] 6
165 Linaclotide [1] Linaclotide[1] Linaclotide; [1] GUCY2C 💬[2] Metabolic pathways, Purine metabolism 💬[2] 6, 97
166 Laninamivir -[0] ---
167 Linagliptin -[0] ---
168 Lebrikizumab [1] Lebrikizumab[1] LEBRIKIZUMAB; [1] IL13 💬[8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[1] 85
169 Lersivirine -[0] ---
170 Linifanib -[0] ---
171 Litronesib -[0] ---
172 Lomitapide [1] Lomitapide[2] Lojuxta; LOMITAPIDE; [1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79
173 Losmapimod [1] Losmapimod[1] LOSMAPIMOD; [4] MAPK11,
MAPK12,
MAPK13,
MAPK14 💬		[62] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬[2] 113, 222
174 Lixisenatide [1] Lixisenatide[1] Lixisenatide; [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 6
175 Latrepirdine [1] Latrepirdine[2] Dimebon; Latrepirdine; [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
176 Lenvatinib -[0] ---
177 Lesinurad -[0] ---
178 Letaxaban -[0] ---
179 Levoglucose -[0] ---
180 Linsitinib [1] Linsitinib[1] Linsitinib; [1] IGF1R 💬[29] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, HIF-1 signaling pathway, Hepatocellular carcinoma, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[1] 232
181 Lorvotuzumab mertansine -[0] ---
182 Lonaprisan -[0] ---
183 Levomilnacipran -[0] ---
184 Lumacaftor [1] Lumacaftor[2] LUMACAFTOR; Orkambi; [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
185 Lipegfilgrastim -[0] ---
186 Lasmiditan -[0] ---
187 Lifitegrast -[0] ---
188 Lomibuvir -[0] ---
189 Lampalizumab -[0] ---
190 Latanoprostene bunod -[0] ---
191 Ledipasvir [1] Ledipasvir[2] Harvoni; Ledipasvir; --[2] 19, 254
192 Liafensine -[0] ---
193 Lirilumab -[0] ---
194 Lusutrombopag -[0] ---
195 Lanopepden -[0] ---
196 Lauric acid -[0] ---
197 Letermovir [1] Letermovir[1] Letermovir; --[1] 85
198 Lonoctocog alfa -[0] ---
199 Lanabecestat -[0] ---
200 Levoketoconazole [1] Levoketoconazole[1] Levoketoconazole; --[1] 75
201 Lorlatinib -[0] ---
202 Lemborexant -[0] ---
203 Lanadelumab -[0] ---
204 Larotrectinib -[0] ---
205 Landipirdine -[0] ---
206 Leniolisib [1] Leniolisib[1] Leniolisib; [3] PIK3CA,
PIK3CB,
PIK3CD 💬		[106] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, Metabolic pathways, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Platinum drug resistance, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[2] 53, 65
207 Lumateperone -[0] ---
208 Lesinidase alfa -[0] ---
209 Landogrozumab -[0] ---
210 Lenzilumab -[0] ---
211 Lifastuzumab vedotin -[0] ---
212 Lumretuzumab -[0] ---
213 Lenabasum [1] Ajulemic acid[1] Ajulemic acid; [1] CNR2 💬[1] Neuroactive ligand-receptor interaction 💬[3] 50, 51, 299
214 Lumicitabine -[0] ---
215 Loncastuximab tesirine -[0] ---
216 Leronlimab -[0] ---
217 Lifirafenib -[0] ---
218 Linrodostat -[0] ---
219 Lucerastat [1] Lucerastat[1] Lucerastat; [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[1] 19
220 Lerociclib -[0] ---
221 Lonapegsomatropin [1] Lonapegsomatropin[1] LONAPEGSOMATROPIN; [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78
222 Lisavanbulin -[0] ---
223 Lorecivivint -[0] ---
224 Lanraplenib [1] Lanraplenib[1] Lanraplenib; --[2] 53, 222
225 Leriglitazone [1] Leriglitazone[1] Leriglitazone; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 20
226 Lefamulin [1] Lefamulin[1] Lefamulin; --[1] 299
227 Lurbinectedin -[0] ---
228 Lecanemab -[0] ---
229 Luspatercept -[0] ---
230 Ligelizumab -[0] ---
231 Lucitanib -[0] ---
232 Lirentelimab [1] Lirentelimab[1] Lirentelimab; [1] SIGLEC8 💬-[1] 98
233 Lobeglitazone -[0] ---
234 Lumasiran [1] Lumasiran[1] LUMASIRAN; [1] HAO1 💬[4] Carbon metabolism, Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Peroxisome 💬[1] 234
235 Levonadifloxacin -[0] ---
236 Lazertinib -[0] ---
237 Lisocabtagene maraleucel -[0] ---
238 Lenacapavir -[0] ---