Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Dextran 1 [1] Dextran[1] Dextran; --[5] 2, 62, 79, 96, 97
2 Dinoprostone -[0] ---
3 Dinoprost -[0] ---
4 Diflunisal [1] Diflunisal[1] Diflunisal; [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 28
5 Disulfiram -[0] ---
6 Dimercaprol [1] Dimercaprol[0] --[5] 49, 51, 84, 85, 299
7 Dexpanthenol -[0] ---
8 Dactinomycin -[0] ---
9 Dacarbazine -[0] ---
10 Danazol [1] Danazol[1] Danazol; [3] AR,
ESR1,
PGR 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[5] 60, 63, 64, 65, 285
11 Demeclocycline hydrochloride -[0] ---
12 Desmopressin [1] Desmopressin[5] DDAVP; Desmopressin; Desmopressin acetate; Desmopressine; Minirin; [2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[6] 6, 64, 72, 75, 225, 288
13 Dexamethasone [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
14 Diazepam [1] Diazepam[1] Diazepam; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 46, 155, 298
15 Diazoxide [1] Diazoxide[1] Diazoxide; [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[2] 13, 193
16 Didanosine [1] Didanosine[1] Didanosine; --[2] 25, 265
17 Digitoxin [1] Digitoxin[1] Digitoxin; [4] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		[18] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 299
18 Digoxin [1] Digoxin[1] Digoxin; [4] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		[18] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 8, 46, 210
19 Dihydrotachysterol [1] Dihydrotachysterol[0] [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[2] 6, 85
20 Diphenhydramine [1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
21 Dipyridamole [1] Dipyridamole[1] Dipyridamole; [2] PDE4A,
PDE5A 💬		[6] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 46, 49, 51, 66, 96, 224
22 Disopyramide -[0] ---
23 Dronabinol [1] Dronabinol[4] DELTA-9-TETRAHYDROCANNABINOL; DRONABINOL; Sativex; Tetrahydrocannabinol; [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[8] 2, 8, 13, 36, 46, 96, 271, 298
24 Doxycycline [1] Doxycycline[4] Doxycyclin; Doxycycline; Doxycycline Hyclate; Doxycycline Tablets; --[16] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
25 Droperidol -[0] ---
26 Dexmedetomidine [1] Dexmedetomidine[4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[13] 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
27 Dichlorphenamide [1] Diclofenamide[1] Dichlorphenamide; [13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 114
28 Dimenhydrinate -[0] ---
29 Desflurane [1] Desflurane[1] Desflurane; --[2] 22, 296
30 Diethylstilbestrol -[0] ---
31 Dapsone [1] Dapsone[1] Dapsone; --[6] 35, 42, 60, 84, 90, 162
32 Doxazosin mesylate [1] Doxazosin[2] CARDURA; Doxazosin; [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 57, 67
33 Diltiazem hydrochloride [1] Diltiazem[2] Diltiazem; Diltiazem Hydrochloride; [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 58, 86
34 Dobutamine hydrochloride [1] Dobutamine[2] Dobutamin; Dobutamine; [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 57, 58, 215
35 Dopamine hydrochloride [1] Dopamine[2] Dopamina; Dopamine; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 7, 74, 299
36 Disopyramide phosphate -[0] ---
37 Dofetilide -[0] ---
38 Dorzolamide hydrochloride [1] Dorzolamide[1] Dorzolamide; [13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90
39 Demecarium bromide -[0] ---
40 Dexchlorpheniramine maleate [1] Chlorpheniramine[1] Clorfenamina; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14
41 Diphenhydramine hydrochloride [1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
42 Donepezil hydrochloride [1] Donepezil[3] ARICEPT; Donepezil; Donepezil hydrochloride; [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
43 Dyphylline -[0] ---
44 Dicyclomine hydrochloride -[0] ---
45 Dolasetron mesylate -[0] ---
46 Dibucaine -[0] ---
47 Dyclonine hydrochloride -[0] ---
48 Doxacurium chloride -[0] ---
49 Diethylcarbamazine citrate -[0] ---
50 Desipramine hydrochloride [1] Desipramine[1] Desipramine; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 120, 156
51 Doxepin hydrochloride [1] Doxepin[1] Doxepin; [3] HRH1,
SLC6A2,
SLC6A4 💬		[5] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 6
52 Dehydroemetine -[0] ---
53 Dezocine -[0] ---
54 Dextromethorphan hydrobromide [1] Dextromethorphan[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
55 Dalfopristin -[0] ---
56 Delavirdine mesylate -[0] ---
57 Dienestrol -[0] ---
58 Diclofenac potassium [1] Diclofenac[3] Diclofenac; Diclofenac Sodium; Diclofenac SR; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271
59 Diclofenac sodium [1] Diclofenac[3] Diclofenac; Diclofenac Sodium; Diclofenac SR; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271
60 Dexamethasone sodium phosphate [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
61 Doxercalciferol -[0] ---
62 Diatrizoate sodium -[0] ---
63 Dimethyl sulfoxide [1] Dimethyl sulfoxide[2] Dimethyl sulfoxide; DMSO; --[1] 226
64 Daptomycin -[0] ---
65 Doramectin -[0] ---
66 Diphenylpyraline hydrochloride [1] Diphenylpyraline[0] [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 98
67 Duloxetine hydrochloride [1] Duloxetine[3] Cymbalta; DULOXETINE; Duloxetine hydrochloride; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13
68 Deferoxamine mesylate [1] Deferoxamine[2] Deferoxamine; DESFERAL; --[3] 46, 284, 286
69 Dexmedetomidine hydrochloride [1] Dexmedetomidine[4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[13] 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
70 Dydrogesterone [1] Dydrogesterone[1] DYDROGESTERONE; [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13
71 Deslanoside -[0] ---
72 Daunorubicin hydrochloride [1] Daunorubicin[1] Daunorubicin; [2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[1] 65
73 Difluprednate -[0] ---
74 Droxidopa [1] Droxidopa[4] DOPS; Droxidopa; L-DOPS; Northera; [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170
75 Doxifluridine -[0] ---
76 Diflorasone diacetate -[0] ---
77 Dibenzthion -[0] ---
78 Dinoprost tromethamine -[0] ---
79 Dihydrocodeine phosphate [1] Dihydrocodeine[0] [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 310
80 Dexamethasone metasulfobenzoate sodium [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
81 Dromostanolone propionate -[0] ---
82 Dimeticone -[0] ---
83 Dothiepin hydrochloride -[0] ---
84 Dexamethasone palmitate [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
85 Diphenylpyraline teoclate [1] Diphenylpyraline[0] [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 98
86 Dexamethasone dipropionate [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
87 Dehydrocholic acid -[0] ---
88 Darifenacin hydrobromide [1] Darifenacin[2] Darifenacin; Emselex; [1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 6, 13
89 Domperidone [1] Domperidone[1] Domperidone; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230
90 Doxapram hydrochloride -[0] ---
91 Dexamethasone valerate [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
92 Doxycycline hyclate [1] Doxycycline[4] Doxycyclin; DOXYCYCLINE; DOXYCYCLINE HYCLATE; Doxycycline Tablets; --[16] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
93 Dicloxacillin sodium [1] Dicloxacillin[1] DICLOXACILLIN; --[1] 299
94 Docetaxel -[0] ---
95 Dexamethasone acetate [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
96 Dihydroergotamine mesylate -[0] ---
97 Desmopressin acetate [1] Desmopressin[5] DDAVP; Desmopressin; Desmopressin acetate; Desmopressine; Minirin; [2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[6] 6, 64, 72, 75, 225, 288
98 Diatrizoic acid -[0] ---
99 Dantrolene sodium [1] Dantrolene[2] Dantrolene; Dantrolene sodium; --[2] 13, 233
100 Doxylamine succinate -[0] ---
101 Dantrolene [1] Dantrolene[2] Dantrolene; Dantrolene sodium; --[2] 13, 233
102 Dicloxacillin [1] Dicloxacillin[1] DICLOXACILLIN; --[1] 299
103 Dipivefrin [1] Dipivefrin[2] Dipivefrin; Dipivefrine; [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6
104 Desogestrel [1] Desogestrel[2] Desogestrel; Désogestrel; [2] ESR1,
PGR 💬		[11] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 230
105 Diethyltoluamide -[0] ---
106 Diphenhydramine salicylate [1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
107 Diloxanide furoate -[0] ---
108 Dronedarone -[0] ---
109 Dimetacrine -[0] ---
110 Dexamethasone acefurate [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
111 Dexamethasone beloxil [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
112 Dinoprostone betadex -[0] ---
113 Diphenhydramine tannate [1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
114 Diphenhydramine laurylsulfate [1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
115 Daclizumab [1] Daclizumab[3] DACLIZUMAB; Zenapax; Zinbryta; [1] IL2RA 💬[11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[8] 13, 56, 60, 65, 97, 107, 283, 284
116 Dalbavancin -[0] ---
117 Dapiprazole hydrochloride -[0] ---
118 Darapladib -[0] ---
119 Darbepoetin alfa -[0] ---
120 Darifenacin [1] Darifenacin[2] Darifenacin; Emselex; [1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 6, 13
121 Darodipine -[0] ---
122 Darunavir [1] Darunavir[1] Darunavir; --[1] 2
123 Dasatinib [1] Dasatinib[1] Dasatinib; [8] ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬		[77] Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[2] 51, 85
124 Dazoxiben hydrochloride -[0] ---
125 Decitabine [1] Decitabine[1] Decitabine; [3] DNMT1,
DNMT3A,
DNMT3B 💬		[3] Cysteine and methionine metabolism, Metabolic pathways, MicroRNAs in cancer 💬[3] 13, 60, 63
126 Decoquinate -[0] ---
127 Dectaflur -[0] ---
128 Deferasirox [1] Deferasirox[2] Deferasirox; Exjade; --[3] 254, 284, 286
129 Deferoxamine [1] Deferoxamine[2] Deferoxamine; DESFERAL; --[3] 46, 284, 286
130 Deflazacort [1] Deflazacort[1] DEFLAZACORT; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 30, 113
131 Demeclocycline -[0] ---
132 Denileukin diftitox -[0] ---
133 Denosumab [1] Denosumab[3] Denosumab; Prolia; XGEVA; [1] TNFSF11 💬[8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[7] 46, 50, 93, 95, 96, 274, 299
134 Depreotide -[0] ---
135 Deracoxib -[0] ---
136 Desirudin -[0] ---
137 Desloratadine [1] Desloratadine[1] Desloratadine; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 13
138 Deslorelin -[0] ---
139 Desmoteplase -[0] ---
140 Desonide -[0] ---
141 Desoximetasone -[0] ---
142 Desoxycorticosterone acetate -[0] ---
143 Desoxycorticosterone pivalate -[0] ---
144 Dexbrompheniramine maleate -[0] ---
145 Dexetimide -[0] ---
146 Dexibuprofen -[0] ---
147 Dexrazoxane [1] Dexrazoxane[1] Dexrazoxane; [2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[1] 13
148 Doramapimod -[0] ---
149 Dextofisopam -[0] ---
150 Dextroamphetamine -[0] ---
151 Dextromethorphan [1] Dextromethorphan[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
152 Dextromethorphan polistirex [1] Dextromethorphan[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
153 Dextrothyroxine sodium -[0] ---
154 Dibotermin alfa [1] Dibotermin alfa[1] BMP-2; [1] BMPR2 💬[7] Axon guidance, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hippo signaling pathway, MicroRNAs in cancer, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[1] 34
155 Dichloralphenazone -[0] ---
156 Dichlorvos -[0] ---
157 Diclazuril -[0] ---
158 Dicumarol -[0] ---
159 Dienogest -[0] ---
160 Diethylpropion hydrochloride -[0] ---
161 Difenoxin -[0] ---
162 Dutasteride [1] Dutasteride[2] Dutasterida; DUTASTERIDE; [2] SRD5A1,
SRD5A2 💬		[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[2] 1, 2
163 Dihydroxyaluminum sodium carbonate -[0] ---
164 Diltiazem malate [1] Diltiazem[2] Diltiazem; Diltiazem Hydrochloride; [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 58, 86
165 Dimethyl fumarate [1] Dimethyl fumarate[3] Dimethyl fumarate; Dimethylfumarat; TECFIDERA; [1] KEAP1 💬[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[5] 13, 49, 51, 86, 296
166 Dioxybenzone -[0] ---
167 Diphenhydramine citrate [1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
168 Diphenidol -[0] ---
169 Diphenoxylate hydrochloride -[0] ---
170 Dipyrithione -[0] ---
171 Dirithromycin -[0] ---
172 Dirlotapide -[0] ---
173 Dobutamine [1] Dobutamine[2] Dobutamin; Dobutamine; [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 57, 58, 215
174 Dobutamine lactobionate [1] Dobutamine[2] Dobutamin; Dobutamine; [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 57, 58, 215
175 Dobutamine tartrate [1] Dobutamine[2] Dobutamin; Dobutamine; [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 57, 58, 215
176 Docosanol -[0] ---
177 Domiodol -[0] ---
178 Dopexamine -[0] ---
179 Doripenem [1] Doripenem[2] DORIBAX; Doripenem; --[1] 299
180 Dornase alfa [1] Dornase alfa[3] DORNASE ALFA; Dornase alpha; Pulmozyme; --[2] 53, 299
181 Doxofylline -[0] ---
182 Doxorubicin [1] Doxorubicin[2] Doxorubicin; Doxorubicin hydrochloride; [2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[5] 26, 28, 34, 65, 331
183 Doxycycline calcium [1] Doxycycline[4] Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets; --[16] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
184 Doxycycline fosfatex [1] Doxycycline[4] Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets; --[16] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
185 Droloxifene -[0] ---
186 Drospirenone -[0] ---
187 Drotrecogin alfa -[0] ---
188 Disodium edetate [1] Edetic acid[1] EDTA; --[2] 51, 60
189 Dalfampridine [1] Dalfampridine[7] 4-Aminopyridine; 4-AP; AMPYRA; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra; [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[5] 3, 4, 6, 13, 14
190 Deproteinized serum -[0] ---
191 d-Camphor and ethanol -[0] ---
192 Dried sodium carbonate -[0] ---
193 d-Camphor -[0] ---
194 Dasatinib [1] Dasatinib[1] Dasatinib; [8] ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬		[77] Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[2] 51, 85
195 Dexelvucitabine -[0] ---
196 dl-Camphor and ethanol -[0] ---
197 Donkey glue [1] Gelatin[3] Gelatin; Gelatine; Sulfur Colloid; --[7] 19, 28, 62, 78, 97, 269, 299
198 Difemerine -[0] ---
199 Drotaverine -[0] ---
200 Diisopromine -[0] ---
201 Dantron -[0] ---
202 Dextranomer -[0] ---
203 Diphenadione -[0] ---
204 Ditazole -[0] ---
205 Dabigatran etexilate [1] Dabigatran etexilate[1] Dabigatran etexilate; [1] F2 💬[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬[1] 51
206 Dimetofrine -[0] ---
207 Dihydralazine -[0] ---
208 Dibrompropamidine -[0] ---
209 Demegestone -[0] ---
210 Demoxytocin -[0] ---
211 Droxicam -[0] ---
212 Dexketoprofen -[0] ---
213 Diacerein [1] Diacerein[1] Diacerein; --[3] 36, 46, 63
214 Diamorphine -[0] ---
215 Dextromoramide -[0] ---
216 Dipyrocetyl -[0] ---
217 Doxefazepam -[0] ---
218 Difetarsone -[0] ---
219 Desaspidin -[0] ---
220 Dixanthogen -[0] ---
221 Droxypropine -[0] ---
222 Dropropizine -[0] ---
223 Dimethoxanate -[0] ---
224 Deptropine -[0] ---
225 Deferiprone [1] Deferiprone[2] Deferiprone; Ferriprox; --[6] 2, 6, 18, 120, 122, 233
226 Defibrotide sodium -[0] ---
227 Danofloxacin -[0] ---
228 Dapiprazole -[0] ---
229 Daunorubicin [1] Daunorubicin[1] Daunorubicin; [2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[1] 65
230 Deanol [1] Deanol[1] Deanol; --[1] 6
231 Delapril -[0] ---
232 Delavirdine -[0] ---
233 Delorazepam [1] Delorazepam[0] [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 6, 46, 97
234 Deltamethrin -[0] ---
235 Desipramine [1] Desipramine[1] Desipramine; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 120, 156
236 Desoxycortone -[0] ---
237 Desvenlafaxine -[0] ---
238 Detomidine -[0] ---
239 Dexamethasone isonicotinate -[0] ---
240 Dexchlorpheniramine [2] Chlorpheniramine,
Dexchlorpheniramine		[2] Clorfenamina; Dexchlorpheniramine; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[3] 13, 14, 49
241 Dexfenfluramine -[0] ---
242 Dexmethylphenidate -[0] ---
243 Dextropropoxyphene -[0] ---
244 Diacetylmorphine hydrochloride -[0] ---
245 Dibekacin -[0] ---
246 Dibenzepin -[0] ---
247 Diclofenac [1] Diclofenac[3] Diclofenac; Diclofenac Sodium; Diclofenac SR; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271
248 Dicycloverine -[0] ---
249 Dihexyverine -[0] ---
250 Diethylcarbamazine -[0] ---
251 Diflorasone -[0] ---
252 Difloxacin -[0] ---
253 Dihydrocodeine [1] Dihydrocodeine[0] [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 310
254 Dihydroergocristine -[0] ---
255 Dihydroergocryptine -[0] ---
256 Dihydroergotamine -[0] ---
257 Dihydroergotoxine [1] Dihydroergotoxine[1] Dihydroergotoxine; --[1] 6
258 Dihydrostreptomycin -[0] ---
259 Dihydroxyacetone -[0] ---
260 Dilazep -[0] ---
261 Diloxanide -[0] ---
262 Diltiazem [1] Diltiazem[2] Diltiazem; Diltiazem Hydrochloride; [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 58, 86
263 Dimefline -[0] ---
264 Dimemorfan -[0] ---
265 Dimetindene -[0] ---
266 Dimetotiazine -[0] ---
267 Diosmin [1] Diosmin[1] DIOSMIN; --[1] 265
268 Diphenoxylate -[0] ---
269 Diphenylpyraline [1] Diphenylpyraline[0] [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 98
270 Diprenorphine -[0] ---
271 Dixyrazine -[0] ---
272 Docetaxel -[0] ---
273 Dolasetron -[0] ---
274 Domperidone maleate [1] Domperidone[1] Domperidone; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230
275 Donepezil [1] Donepezil[3] ARICEPT; DONEPEZIL; Donepezil hydrochloride; [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
276 Dopamine [1] Dopamine[2] Dopamina; Dopamine; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 7, 74, 299
277 Dorzolamide [1] Dorzolamide[1] Dorzolamide; [13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90
278 Dosulepin -[0] ---
279 Doxapram -[0] ---
280 Doxazosin [1] Doxazosin[2] CARDURA; DOXAZOSIN; [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 57, 67
281 Doxepin [1] Doxepin[1] Doxepin; [3] HRH1,
SLC6A2,
SLC6A4 💬		[5] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 6
282 Doxycycline [1] Doxycycline[4] Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets; --[16] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
283 Doxylamine -[0] ---
284 Duloxetine [1] Duloxetine[3] CYMBALTA; Duloxetine; Duloxetine hydrochloride; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13
285 Dyclonine -[0] ---
286 Deserpidine -[0] ---
287 Dacetuzumab -[0] ---
288 Dapagliflozin [1] Dapagliflozin[1] Dapagliflozin; [1] SLC5A2 💬-[2] 49, 222
289 Darinaparsin -[0] ---
290 Deferitrin -[0] ---
291 Degarelix -[0] ---
292 Dexlansoprazole [1] Dexlansoprazole[1] Dexlansoprazole; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 98
293 Delafloxacin -[0] ---
294 Denenicokin -[0] ---
295 Dutogliptin -[0] ---
296 Dulanermin -[0] ---
297 Dirucotide [1] Dirucotide[1] Dirucotide; --[1] 13
298 Davunetide [1] Davunetide[1] Davunetide; --[3] 5, 7, 127
299 Danegaptide -[0] ---
300 Davalintide -[0] ---
301 Dilmapimod -[0] ---
302 Dinaciclib -[0] ---
303 Duvoglustat [1] Duvoglustat[3] 1-deoxynojirimycin; Deoxynojirimycin; Duvoglustat; [1] GAA 💬[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬[1] 256
304 Dabigatran [1] Dabigatran[1] Dabigatran; [1] F2 💬[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬[4] 51, 85, 91, 124
305 Dalcetrapib -[0] ---
306 Dalotuzumab -[0] ---
307 Delamanid -[0] ---
308 Dacomitinib -[0] ---
309 Danoprevir -[0] ---
310 Dexpramipexole [1] Dexpramipexole[1] Dexpramipexole; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 2
311 Dulaglutide [1] Dulaglutide[2] Dulaglutide; Trulicity; [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[2] 13, 299
312 Dabrafenib [1] Dabrafenib[1] Dabrafenib; [1] BRAF 💬[44] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Bladder cancer, Breast cancer, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanoma, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Regulation of actin cytoskeleton, Renal cell carcinoma, Serotonergic synapse, Thyroid cancer, Vascular smooth muscle contraction, cAMP signaling pathway, mTOR signaling pathway 💬[1] 34
313 Daclatasvir -[0] ---
314 Dolutegravir [1] Dolutegravir[2] Dolutegravir; Triumeq; --[2] 2, 265
315 Dalantercept -[0] ---
316 Dasolampanel etibutil -[0] ---
317 Delanzomib -[0] ---
318 Dexmecamylamine -[0] ---
319 Drisapersen [1] Drisapersen[1] Drisapersen; [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113
320 Delparantag -[0] ---
321 Dusigitumab -[0] ---
322 Demcizumab -[0] ---
323 Dupilumab [1] Dupilumab[2] DUPILUMAB; Dupixent; [1] IL4R 💬[8] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[4] 51, 98, 160, 162
324 Danirixin -[0] ---
325 Deferitazole [1] Deferitazole[1] Deferitazole; --[1] 284
326 Dianexin -[0] ---
327 Delcasertib -[0] ---
328 Dacomitinib -[0] ---
329 Dactolisib -[0] ---
330 Dasabuvir -[0] ---
331 Deleobuvir -[0] ---
332 Duvelisib -[0] ---
333 Dinutuximab -[0] ---
334 Decernotinib -[0] ---
335 Defactinib -[0] ---
336 Dianhydrogalactitol -[0] ---
337 Doravirine [1] Doravirine[1] Doravirine; --[1] 265
338 Dasotraline -[0] ---
339 Deutetrabenazine [1] Deutetrabenazine[1] Deutetrabenazine; [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
340 Damoctocog alfa pegol -[0] ---
341 Daratumumab [1] Daratumumab[2] DARATUMUMAB; Darzalex; [1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[5] 16, 28, 49, 63, 222
342 Deoxycholic acid [1] Deoxycholic acid[1] Kybella; --[1] 34
343 Durvalumab [1] Durvalumab[1] Durvalumab; [1] CD274 💬[2] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬[1] 85
344 Desfesoterodine -[0] ---
345 Daprodustat -[0] ---
346 Decoglurant -[0] ---
347 Dapansutrile -[0] ---
348 Dexisometheptene mucate -[0] ---
349 Dezapelisib -[0] ---
350 Depatuxizumab -[0] ---
351 Depatuxizumab mafodotin -[0] ---
352 Darolutamide -[0] ---
353 Delgocitinib -[0] ---
354 Domagrozumab [1] Domagrozumab[1] PF-06252616; [1] MSTN 💬[1] Cytokine-cytokine receptor interaction 💬[1] 113
355 Dotinurad -[0] ---
356 Difelikefalin -[0] ---
357 Diroximel fumarate [1] Diroximel fumarate[1] Diroximel fumarate; --[1] 13
358 Dolcanatide -[0] ---
359 Dapivirine -[0] ---
360 Difamilast -[0] ---
361 Dorzagliatin -[0] ---
362 Dasiglucagon -[0] ---
363 Dostarlimab -[0] ---
364 Duvortuxizumab -[0] ---
365 Darvadstrocel [1] Darvadstrocel[2] Alofisel; DARVADSTROCEL; --[1] 96
366 Deutivacaftor [1] Deutivacaftor[1] DEUTIVACAFTOR; [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
367 Dezamizumab [1] Dezamizumab[1] Dezamizumab; [1] APCS 💬-[1] 28
368 Donanemab -[0] ---
369 Durlobactam -[0] ---
370 Danicopan [1] Danicopan[1] DANICOPAN; [1] CFD 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[2] 62, 222
371 Dilpacimab -[0] ---
372 Dubermatinib -[0] ---
373 Duligotuzumab -[0] ---
374 Dusquetide -[0] ---
375 Daxdilimab -[0] ---
376 Dirocaftor -[0] ---
377 Deucravacitinib [1] Deucravacitinib[1] Deucravacitinib; [1] TYK2 💬[16] Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis 💬[2] 96, 97
378 Dengue tetravalent vaccine, live -[0] ---